NEJM Catalyst

📣 In the April 2026 issue: cancer, musculoskeletal, behavioral health, and hypertension care; social needs interventions; vaccines; corporatization of medicine; health care workforce; health system turnaround; neonatal toxicology testing. 🧵👇 📖 nej.md/4rCKr11

Yale New Haven Children’s Hospital developed a testing protocol with specific clinical indications for testing and clear informed consent expectations: nej.md/4snjNdU

among successfully reached members, compared with members who could not be reached, for Medicaid beneficiaries with both high clinical risks and high social risks: nej.md/4sVWVSF (2/2)

In an evaluation of its Community Connected Care social needs intervention program, Elevance Health uses an adjusted difference-in-differences analysis to estimate total allowed health care cost savings of $181 per member per month in the subsequent 6-month follow-up period (1/2)

Oklahoma’s only academic health system, OU Health, brings itself out of clinical, financial, and cultural distress by creating a shared vision, leading with safety as foundational priority, and aligning leadership and accountability across the enterprise: nej.md/4lEBBi8

was associated with changes in surgical indications, improved average patient outcomes, and reduced low-value procedures: nej.md/3OdjQKj (2/2)

In a 4-year study of cataract surgeons, access to an unmasked peer benchmarking dashboard supported by a noncoercive, nonpunitive organizational culture (1/2)

The Indianapolis Health Equity, Access, Outreach, and Treatment Collaborative was designed to help patients build the knowledge, skills, and support needed to manage their cardiovascular health: nej.md/475raxW

selected patient-reported clinical experience and satisfaction metrics suggest a beneficial relationship that expands access to care: nej.md/475qWa4 (2/2)

One year after Emplify Health by Bellin launched a pilot study with real-time and asynchronous virtual support for patients in need of musculoskeletal care through a third-party vendor, (1/2)

increased monthly utilization of BH care by nearly 10%, and has helped patients achieve remission of moderate-to-severe depression and anxiety within four and five sessions, respectively: nej.md/4rxKZFz (2/2)

An initiative by Highmark Health to integrate a third-party company that provides virtual behavioral health care has expanded available BH providers by about 46%, (1/2)

a reduction in moderate hyponatremia from 3.4% to 1.3%, and a reduction in severe hyponatremia from 0.57% to 0.22%: nej.md/4rAOw5S (2/2)

The deployment of a best practice alert for at-risk total joint arthroplasty patients is associated with a 1-year reduction in the rate of postsurgery mild hyponatremia from 25.9% to 12.6%, (1/2)

that could serve as a scalable blueprint for expanding access to cancer treatment across diverse populations and geographies: nej.md/4bvzEjd (2/2)

An innovative care delivery model at Mayo Clinic integrates virtual oversight, remote patient monitoring, mobile health services, and a unified software platform connected to the electronic medical record (1/2

An Insights Council survey finds patient hesitancy is the top challenge, especially in the U.S., for health care organizations’ vaccination programs. U.S. Council members lack confidence in public health agencies’ ability to support vaccination efforts: nej.md/40VP37L

The April 2026 issue of NEJM Catalyst Innovations in Care Delivery is now live: nej.md/4rCKr11

How Physician Coaches Can Be Beneficial - read or listen to our Q&A with Scott Friedenberg, Geisinger Health: nej.md/3PkfEc3

Read the letter from our editors: nej.md/4rzXH6E 2/2

Our May issue covers cancer care, musculoskeletal care, behavioral health care, hypertension control, social needs interventions, vaccines, the corporatization of medicine, the health care workforce, a health system turnaround, and neonatal toxicology testing. 1/2