Neural Cell News

Can't keep up with all the current breakthroughs in neuroscience? Worry not! We have got you covered with Neural Cell News, a free email newsletter from Science News by @STEMCELLTech. 🖱️ Hit subscribe: bit.ly/4kkWMEu

Drs. Rony Chanoch-Myers, @hara_toshiro, Alissa Greenwald (@alissacg), and colleagues uncover a blueprint for the invasive potential of glioblastoma cell states and of the programs associated with invasion across different scales. go.nature.com/4rLVLYB

TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis. Discover more here: 🔗 bit.ly/4cTUHyo

Researchers found that Aβ42 oligomers may contribute to neuronal toxicity by inducing changes in the identity, distribution and balance of vesicular components associated with the endo-lysosomal pathway. 🔎 bit.ly/4uFBKGa

Congratulations to researchers alongside @LauraKonig17, Drs. Steven Rodriguez (@SteveRodz1), and Mark Albers at @harvardmed and their recent publication reporting that TYK2 mediates neuroinflammation in Alzheimer’s disease brains with TDP-43 pathology. go.nature.com/3NE2zcY

Researchers from @UnivPoitiers alongside Antoine Retho, Annousha Devi Govindan, and Dr. @AfsanehGaillard assessed the contribution of tissue clearing and 3D image analysis to in vitro modeling of human cortical development. 🔖 go.nature.com/412DMSV

Researchers alongside Dr. @DomenicPratico1 provide a concise review of the role and mechanistic implications of TREM2 in neurodegeneration and neuroinflammation. 🔖 go.nature.com/4uhoY06

Researchers identify FOXJ3 pathogenic variants in patients with autosomal dominant focal epilepsy and focal cortical dysplasia. Learn more at @NatureComms: 🔗 go.nature.com/3NvWP4X

A research team from @CHUnantes shows that SAMP8 mice display a gut amyloid pathology, an alteration of enteric nervous system connectivity and gut defects prior to memory decline. 🔗 go.nature.com/40jO80x

🔬 Scientists assess the impact of ubiquitous and neuronal promoters on Parkin gene expression and mitophagy induction in human iPSC-derived dopaminergic neuronal assays. go.nature.com/4b1dQx0

Researchers observed a marked decline in the number of oligodendrocyte progenitor cells during aging, notably within the subpopulation highly expressing Acss2, which encodes acetyl-CoA synthetase 2. 📘 @NatureAging 🔗 go.nature.com/4b3DvDJ

Published in @CellCellPress! Researchers develop a next-generation extracellular targeted protein degradation platform for degrading extracellular amyloid-β in Alzheimer's disease. Learn more: 💡 bit.ly/3NiKeSu

Fascinating read! 👀

In this review, scientists assess different factors that may contribute to glioma malignancy, such as the presence of glioma stem cells, cellular heterogeneity, and selection for specific genotypes. 📖 bit.ly/4l6WPVu

The following review explores molecular processes by which adiponectin changes important signaling pathways, stop microglial activation, and improve neuronal survival. 📖 bit.ly/4bhLTRn

Scientists investigated the therapeutic potential and mechanism of action of the natural compound β-asarone in Alzheimer’s disease models. 🔗 bit.ly/46wdiMV

Researchers identify a mitochondrion–immunity–metabolism axis linking neuronal mitochondrial damage to chronic seizures. @PNASNews 📘 bit.ly/4r33TUd

Researchers led by Dr. Simon Storevik summarize current knowledge on mitochondrial exchange in glioblastoma via tunneling nanotubes, tumor microtubes, and potentially via extracellular vesicles. 🔗 bit.ly/4l1sWpE

Scientists synthesize emerging insights from single-cell and spatial transcriptomics to decode myeloid dynamics across distinct #glioblastoma anatomical compartments. 🔗 bit.ly/4rwjM6J

Cancer Neuroscience and signaling pathways! In this review, scientists provide a full account of the intersection between neuroscience and cancer research. 📘 @sigtrans_sttt 🔖 go.nature.com/4aSmMTX