Nityanand Bolshette

New! Online now: Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome dlvr.it/TBWv4r

CO2, regulation and metabolism. @NicoleMFenton @BrownLabUNSW explore a #PLOSBiology study that provides the first link between #CarbonDioxide and the master transcriptional regulator of #cholesterol homeostasis. Paper: plos.io/3QEDs7f Primer: plos.io/46sLSV2

How do mammals adapt to changes in #CarbonDioxide levels? @lab_asher reveals an interaction between #CO2, SREBP2 activation & regulation of #cholesterol levels, suggesting that cellular cholesterol levels can be modulated by CO2 via SREBP2 #PLOSBiology plos.io/3QEDs7f

Our review 'Circadian regulation of liver function: from molecular mechanisms to disease pathophysiology' is now online. @NityanandBolsh2 nature.com/articles/s4157…

New content online: Circadian regulation of liver function: from molecular mechanisms to disease pathophysiology dlvr.it/SqNBh3

Congratulation to Gal Manella on publishing another paper! 🥳 We wish you many more! Input integration by the circadian clock exhibits nonadditivity and fold-change detection doi.org/10.1073/pnas.2…

High altitude affects daily variations in human transcriptome. Another fruitful collaboration between @lab_asher and Samuel Verges. @GalManella and @SaarEzagouri_RD joined forces on this one. Thanks to the 5300 expedition conducted in Peru. @CellReports cell.com/cell-reports/f…

Check out this awesome podcast with our talented PhD student @SaarEzagouri_RD discussing our work on time dependent exercise capacity 💪🐁🏃🏅