Oncogene Journal

METTL16 is critical modulator of proteasome inhibitor resistance in multiple myeloma, acting through an m⁶A‑independent translational mechanism that enhances PERK–eIF2α dysregulation. Read more >>>> nature.com/articles/s4138…

Read more about how loss of the chromatin remodeler CHD1 induces synthetic lethality in MYC‑driven #breast cancer by disrupting chromatin accessibility, triggering nucleolar stress, and activating p53. 📖🧪🔬 nature.com/articles/s4138…

New study uncovers a neutrophil‑dependent anti-tumor mechanism of dexamethasone, revealing a GR‑driven ROS axis that suppresses tumour growth and extends survival! Read more 📖🔬🧪 nature.com/articles/s4138…

New research uncovers how KRAS‑driven extrachromosomal DNA fuels #tumour evolution and therapy resistance in gastric cancer. nature.com/articles/s4138…

Agonist of co-stimulatory factor GITR revives tumor-killing CD8+ T cells, blocks suppressive Tregs through NF-κB/KALRN signaling, and teams up with anti-PD-1 for stronger glioblastoma control—boosting TIL therapy. Read more about these findings >>>> nature.com/articles/s4138…

Discover how the RNA‑binding protein L1TD1 drives mucus production and accelerates #colorectal mucinous adenocarcinoma. nature.com/articles/s4138…

New research uncovers how the RNA helicase DDX39A fuels glioblastoma growth and immune suppression by stabilizing WISP1 mRNA—blocking DDX39A slows tumor progression and offers a new path for glioma therapy. 🧠🔬 #CancerResearch #Glioblastoma nature.com/articles/s4138…

New research reveals that obesity and high breast density together create an immune environment that fuels #breast cancer metastasi. #BreastCancerResearch #Immunology #TranslationalScience nature.com/articles/s4138…

A novel regulatory mechanism of #PituitaryAdenoma stemness 🔬nature.com/articles/s4138…

An #OpenAccess insight into #ColonCancer tumourigenesis through a non-canonical GLI-PI3K positive loop. 👇 nature.com/articles/s4138…

How does FUS regulate androgen receptor activity during #ProstateCancer progression? Researchers @ImperialSandC & @Uni_of_Essex, including @GregBrooke4, @DrDALEACH & Prof Charlotte Bevan, share exciting findings in @oncogenejournal. Grab a ☕ & read: doi.org/10.1038/s41388…

🔬USP17 as a key regulator of β-catenin signaling nature.com/articles/s4138… #CRC #ColorectalCancer

An insight into the mechanism mediating the anticancer properties of a metabolite of vitamin D 💊nature.com/articles/s4138… #BreastCancer

PD-1-ERK signalling axis accelerates tumorigenesis in #OvarianCancer nature.com/articles/s4138…

Could sortilin expression be used to predict the efficacy of anti-EGFR therapies in lung adenocarcinoma? 🔎nature.com/articles/s4138… #OpenAccess #LungCancer

A novel metabolic-epigenetic mechanism driving immune evasion in triple negative #BreastCancer nature.com/articles/s4138… #TNBC

Read about the newly identified role of PRR15/NF-κB/FDX1 axis in renal cell carcinoma. nature.com/articles/s4138… #KidneyCancer

A potential therapeutic option for non-small cell lung cancer (#NSCLC) with spinal metastasis: nature.com/articles/s4138…

A novel mechanism of P53 regulation in #BladderCancer 🧪nature.com/articles/s4138… #CancerResearch

A novel agent has been identified that targets different #OvarianCancer subtypes, showing cancer cell-selectivity. 🔬nature.com/articles/s4138… #OpenAccess