Opentrons

New in @PlantPhys | BOTany Methods is an open-source toolkit making robotic lab automation accessible for plant science labs. Developed by Dr. Voiniciuc’s team, the platform runs @opentrons OT-2 systems without custom coding; open-source on @github. 🔗bit.ly/3MPsa2h

Any fun suggestions for a name for our newest lab member? @opentrons

It is great to see the use of ⁦@opentrons⁩ ! 👏🏼 share.google/MEPSqKLJB6otJE…

Thanks GEN for a thoughtful piece on how AI and robotics will change(and are already changing) ‘omics workflows.

🧬 Cleaner library prep, fewer contamination risks Library prep workflows often include multiple thermocycling steps, each requiring lids to be removed and replaced. When this isn’t done consistently, samples are more vulnerable to cross-contamination, evaporation, and variability across incubation cycles. The Opentrons Tough Auto-Sealing Lids automate this entire process, placing, sealing, removing, and replacing lids between every incubation step using the Flex Thermocycler and Flex Gripper. No manual sealing, no workflow interruptions. Why they matter in library prep: 🧪 Fresh, repeatable seals for every incubation step 🛡️ Reduced contamination and evaporation during long or multi-step protocols 🤖 Fully automated handling, directly on deck 📏 SBS format, polysulfone construction, 20 lids per pack 🎁 Limited-time offer: Buy an Opentrons Thermocycler or Stacker and get a free box of Auto-Sealing Lids to try out. Already own one? Reach out to your sales rep for a free trial box. Product Link: hubs.ly/Q03XSs3T0

Unlock faster antibody discovery in 4 weeks with NeoKit.🔬 Join us for a webinar tomorrow, December 11th, covering Neochromosome’s Antibody Discovery Toolkit and how automated protein-purification workflows are running on the Opentrons Flex. You will learn how switchable yeast, antibody libraries, and laboratory robotics enable four-week hit discovery. What you’ll learn: 🧬 Acceleration of antibody discovery using the neoSwitch switchable yeast display and secretion platform 🧪 How Neo designs practical, end-to-end discovery campaigns 🤖 How protein-purification steps are automated on the Opentrons Flex Speaker Steven Thomas, Director of Business Development, Neochromosome Steven brings more than twelve years of hands-on and customer-facing experience across gene synthesis, variant library construction, phage and yeast display, and full antibody discovery workflows. Register for tomorrow's webinar here: hubs.ly/Q03XKmSN0

Flex just got even more capable.✨ Our newest software update brings smarter liquid handling, cleaner workflows, and human-like pipetting behavior to automated protocols. 🚀 Smarter pipetting, automatically Dynamic Liquid Tracking on the Flex continuously adjusts tip depth during aspirate/dispense and mixing, maintaining the perfect submerge height without manual tuning. No more trial-and-error offsets, even as liquid levels change. 💧 Cleaner, more accurate liquid handling By avoiding unnecessary tip submergence, the Flex reduces droplet carry-over, contamination, and sample loss, while improving precision for viscous, volatile, or low-volume liquids. 🔄 Mix, move, and pipette like a human New movement-aware functions (including dynamic_mix()) now support two-point mixing and mixing while in motion, unlocking faster workflows, better reagent recovery, and more reproducible results across wells, reservoirs, and plates. Upgrade today and see how much smoother automation can be.

🔬 Lab Automators: 2025 Finale — Automate & Celebrate Opentrons x MilliporeSigma Raise a glass to new possibilities and get hands-on time with the Automated Assay Workstation (AAW) and Luminex Intelliflex. Explore how accessible automation and industry-leading assay expertise come together to streamline multiplex workflows with greater efficiency and consistency. 📅 Tuesday, December 16, 2025 🕕 6:00–10:00 PM 📍 Catalyst Restaurant, 300 Technology Square, Cambridge, MA Meet specialists from Opentrons, MilliporeSigma, and Luminex, see the AAW + Intelliflex in action, and walk away with practical workflow tips to bring back to your lab. 🔗 Full details & registration: hubs.ly/Q03WJ64x0

🔬 Live Webinar: Automated Recombinant Protein Expression See how APEX uses the open-source and affordable Opentrons OT-2 to automate every major step of E. coli expression. Transformation, plating, colony sampling, culturing, and induction all run with precision and consistency, giving you a faster and more scalable workflow. We will share real data across plasmids from 2.7–17.7 kb and proteins from 27–222 kDa, showing how automation removes variability and accelerates discovery. What you’ll learn: 🧪 How APEX automates the full expression workflow 🧪 Optimization strategies for high-throughput expression 🧪 Troubleshooting tips for reproducible results 🎙️ Speakers: Giovanni Stracquandanio, University of Edinburgh Martyna Kasprzyk, University of Edinburgh 📅 Dec 3 ⏰ 10:00 AM EST / 07:00 AM PST / 03:00 PM GMT 👉 Register: hubs.ly/Q03VKsGT0

🔬 Grab a coffee with us and jump into AI-driven automation. We’re hosting a hands-on workshop at the SLAS–ELRIG Meet-Up in London, where the morning opens with coffee, refreshments, and an inside look at how AI can streamline liquid-handling workflows. Throughout the session, you’ll work directly with our team, explore flexible automation on the Opentrons Flex, and see how AI reduces manual steps in protocol design and day-to-day lab work. 📍 Knowledge Quarter – London, UK 🗓️ December 2, 2025 ☕ Morning coffee and refreshments served from 09:30 In the workshop: 🤖 Build workflows with Opentrons AI + the Python API 🧬 Apply practical protocol-design strategies 🔧 Join guided pipetting modules 🧪 Watch live Flex demonstrations 💡 Bring your own workflow challenge to discuss 👉 Register: hubs.ly/Q03VJZBn0 (Please register for both the main meet-up and the workshop.)

🔬 Grab a coffee with us and jump into AI-driven automation. We’re hosting a hands-on workshop at the SLAS–ELRIG Meet-Up in London, where the morning opens with coffee, refreshments, and an inside look at how AI can streamline liquid-handling workflows. Throughout the session, you’ll work directly with our team, explore flexible automation on the Opentrons Flex, and see how AI reduces manual steps in protocol design and day-to-day lab work. 📍 Knowledge Quarter – London, UK 🗓️ December 2, 2025 ☕ Morning coffee and refreshments served from 09:30 In the workshop: 🤖 Build workflows with Opentrons AI + the Python API 🧬 Apply practical protocol-design strategies 🔧 Join guided pipetting modules 🧪 Watch live Flex demonstrations 💡 Bring your own workflow challenge to discuss 👉 Register: hubs.ly/Q03V1Xjx0 (Please register for both the main meet-up and the workshop.)

🔬 Live Webinar: Automated Recombinant Protein Expression See how APEX uses the open-source and affordable Opentrons OT-2 to automate every major step of E. coli expression. Transformation, plating, colony sampling, culturing, and induction all run with precision and consistency, giving you a faster and more scalable workflow. We will share real data across plasmids from 2.7–17.7 kb and proteins from 27–222 kDa, showing how automation removes variability and accelerates discovery. What you’ll learn: 🧪 How APEX automates the full expression workflow 🧪 Optimization strategies for high-throughput expression 🧪 Troubleshooting tips for reproducible results 🎙️ Speakers: Giovanni Stracquandanio, University of Edinburgh Martyna Kasprzyk, University of Edinburgh 📅 Dec 3 ⏰ 10:00 AM EST / 07:00 AM PST / 03:00 PM GMT 👉 Register: hubs.ly/Q03V34kY0

Automate your Evosep Evotip clean-up — here’s how the Opentrons Flex Resin Tips Adapter Set works Manual protein sample clean-up can slow down your LC-MS workflow. With the Opentrons Flex Resin Tips Adapter Set, the Opentrons Flex® automates third-party Evotip loading from start to finish. Here’s how it works: 🧪 Load your Evosep Evotips into the Opentrons Flex resin tips adapter on the Opentrons Flex deck. 💧 The Opentrons Flex 96-Channel Pipette dispenses solvent and digested samples for peptide capture. 🔒 Auto-sealing and precise pressure control ensure consistent desalting and storage of samples. The result: reproducible protein clean-up in less time, with performance that matches manual prep. 🎥 Experience the virtual demo: hubs.ly/Q03TNcYG0

🔬 Heading to the SLAS–ELRIG Meet-Up: AI in Automation? Join us on December 2nd in London for a hands-on morning workshop focused on elevating automation in liquid handling. We’ll walk through flexible, AI-driven workflows, live demos with the Opentrons Flex, and practical insights into how AI can streamline protocol development and everyday lab operations. 📍 Knowledge Quarter – London, UK 🗓️ December 2, 2025 Registration, coffee, and refreshments start at 09:30 to kick off the morning. What’s included: 🤖 Hands-on sessions with Opentrons AI + Python API 🧬 Practical protocol design with our Protocol Designer 🔧 Guided modules, pipetting sessions, and access to our team 💡 Bring your own workflow challenge 🧪 Live demonstrations with the Opentrons Flex 👉 Register here: hubs.ly/Q03TlfM_0 (Please register for both the main meet-up and the workshop.)

🔬 Opentrons is on the road this week, meeting with scientists across omics and molecular diagnostics. First stop: NextGen Omics, Spatial & Data 2025 📍 Novotel London West, UK 📅 November 13–14 Join our talk on how automation is reshaping sample prep across omics workflows, and meet the team to see the Opentrons Flex in action. Then we’re at the AMP 2025 Annual Meeting & Expo 📍 Boston Convention and Exhibition Center, Boston, MA 📅 November 11–15 Visit Booth 1130 to learn how automated liquid handling is helping molecular diagnostics labs improve consistency, reduce hands-on time, and streamline sample-to-answer workflows. Let’s connect and talk about how automation can accelerate your lab’s work.

🔬 Big news from Neochromosome, part of Opentrons Labworks! Neo and GlobalBio have launched pre-transformed scFv libraries in the switchable neoSwitch™ yeast platform, making in-house antibody discovery faster, more affordable, and more accessible than ever. This turnkey solution integrates GlobalBio’s validated ALTHEA Libraries™ directly into Neo’s neoSwitch™ yeast strain, enabling rapid screening, seamless transitions from display to secretion mode, and lead identification in just weeks instead of months. 💡 “With a target antigen in hand, researchers can start screening immediately and identify high-quality leads at a fraction of the traditional cost,” said Leslie Mitchell, PhD, CSO of Opentrons. Learn more about how Neo is transforming biologics discovery: 👉hubs.ly/Q03SPHM30

🌍 The Opentrons team is live right now at PEGS Europe 2025 in Lisbon, and heading next to NextGen Omics 2025 in London later this week! 🔬 PEGS Europe 2025 📍 Lisbon Congress Centre, Portugal 📅 November 11–13 Visit our booth to see how Opentrons automation accelerates protein and antibody discovery with flexible, scalable solutions. 🧬 NextGen Omics, Spatial & Data 2025 📍 Novotel London West, UK 📅 November 13–14 At this event you can join our upcoming talk on how automation is reshaping sample prep for omics workflows. If you’re at either event, come connect with the team and see how automation can move your research forward.

🧬 We’re live at HUPO 2025 in Toronto! If you’re here this week, stop by booth #304 to see how Opentrons automation is transforming proteomics and mass spectrometry. 🤖 Get a hands-on demo of the Opentrons Flex 🧫 Learn about our automated peptide prep workflows 🎤 Don’t miss our seminar, “Scaling Proteomics with Automation: Strategies for Throughput and Robustness” 📅 Wednesday, Nov 11, 8:00 AM 📍 Pier 4 & 5 Come connect with our team and see how automation can accelerate your research.

New: Fully automated Evotip loading with the Opentrons Flex Resin Tips Adapter Set What if you could automate one of the most time-consuming steps in proteomics, completely hands-off, across 96 samples at once? Now you can. The new Opentrons Flex® Resin Tips Adapter automates protein sample clean-up using third-party Evosep Biosystems Evotips, pairing throughput with precision for peptide capture and wash steps. Using an Opentrons-verified protocol, this integration with the Opentrons Flex delivers consistent performance and saves hours of bench time, all in a compact, accessible format. 📍 At World HUPO in Toronto this week? Stop by the Opentrons booth to learn how we’re making automated proteomics more accessible. Learn more: hubs.ly/Q03Sr3RW0

🔬 We’re heading to PEGS Europe 2025 in Lisbon, November 11–13! Join us for one of the leading events in protein & antibody engineering, and see how automation is helping scientists scale biologics R&D faster and more reproducibly. 💡 Visit the Opentrons team to learn more about automating liquid handling with the Opentrons Flex. Let’s connect and talk about how your lab can accelerate discovery. 👉 hubs.ly/Q03S3Y3x0