Peter Mantas

12.3K posts

Peter Mantas

@peter_mantas

LO biotech and life sciences. Avid soccer fan. DMs open. Nothing is financial advice. Chat: https://t.co/9El5QOyuXg

Toronto, Ontario Katılım Ocak 2021

905 Takip Edilen8.5K Takipçiler

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Peter Mantas@peter_mantas·27 Nis

I flew to Baltimore with a thesis and I left with something harder to quantify. This is by far the most important (and moving) piece I've written — on HD, on $QURE, and on what the FDA has done to people who deserve better. Share if you can. Link below.

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Wassim Laroussi@WassimLaroussi3·1d

Site still under construction - but this is one of the valuable views I can share with you today. Stocks with most buys/increases by 50+ Biotech funds. Surprised to see $CMPS in second place. Researching and likely buying it Monday!

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Peter Mantas@peter_mantas·2h

@SushantJos39350 They deserve it

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Sushant Joshi@SushantJos39350·2h

@peter_mantas Aston Villa

GIF

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Peter Mantas@peter_mantas·4h

Worst May I’ve seen in my life tbh

Greg Brady@gregbradyx

We were supposed to get over 20C today for a high temperature. Likely not happening now. If it doesn’t happen, today marks the 209th consecutive day Toronto hasn’t had a day over 20 degrees for a high temperature (since mid-October). The last day AT 20 degrees was April 14th - an incredibly unusual run of 32 straight spring days without it happening. A thoroughly dark run for spring weather in the history of my life, anyway.

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Peter Mantas@peter_mantas·3h

@gtfinchy @DotknightWang @twiii_podcast Get ready for more Glenn!

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Glenn Fincher@gtfinchy·3h

@peter_mantas @DotknightWang @twiii_podcast Canadian asshole shilling on the firing of our medical experts.

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Peter Mantas@peter_mantas·22h

We wrote letters, met management teams, spoke with advocates and lobbyists, exposed Arnold Ventures, and went deep down the rabbit hole on this one. Result: Makary out. Hoeg out. Prasad out. Szarama out. All discussed on my last podcast with @twiii_podcast before it happened. Now the important part: I fully endorse @houmanhemmati for FDA Commissioner. We need evidence-based leadership that actually understands next-generation biologics, cell & gene therapy, and advanced medicines if America wants to stay ahead of China. Most importantly, rare disease families deserve regulators who understand urgency, scientific nuance, and the reality that doing nothing is also a decision.

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Amarillo Slim@Amarillo_Slim1·22h

Cue: Purge music

Amarillo Slim@Amarillo_Slim1

Makary is a puppet of Arnold Ventures along with other personnel that have infected the FDA (Vinay, Szarama, Tracy Beth, Traficant, etc). They are all under influence to push forward a socialistic view of HC that is in contradiction of the admin’s agenda & innovation in biotech.

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Peter Mantas@peter_mantas·4h

@Amarillo_Slim1 Preach Amarillo

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Amarillo Slim@Amarillo_Slim1·4h

This guy is a complete Makary simp that has continuously supported incompetence. Instead of tweeting nonstop, doing podcasts and being a TikTok doctor, you should focus on helping patients. Pathetic that ppl like this hold an MD title in America

Anish Koka, MD@anish_koka

Disagree. Competent people should stay far away from whatever’s going on over there.

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Peter Mantas@peter_mantas·4h

@stuartbuck1 @mike98572986 @CommonSense3241 @TinMarkProd @Tim_Corr Oh I get it now, didn’t realize who I was talking to. Don’t worry man, we will get this one over the line (because the biology works) and your whole AV crew will be exposed. More shock and awe coming! Go back to sleep.

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Peter Mantas@peter_mantas·4h

@stuartbuck1 @mike98572986 @CommonSense3241 @TinMarkProd @Tim_Corr What? I literally gave you a handful of examples across many where therapies were rejected despite p3 efficacy. AA is a whole other procedural framework. P3 is a different ballgame.

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Tim@Tim_Corr·9h

Szarama staying at the FDA in any capacity is a problem. She wasn’t just some random FDA hire. She was at Arnold Ventures, then went to ARPA-H for a few months, then was brought into CBER leadership by Vinay Prasad. That path deserves a lot more attention. And when you look into ARPA-H, the original HARPA/ARPA-H concept traces back to a white paper co-authored by Michael Stebbins, who was previously an executive at the Laura and John Arnold Foundation. It’s also important that Pink Sheet reported in Sept. 2025 that Szarama was “on detail to the CBER director’s office from ARPA-H. So what exactly was her status at FDA? Was she a formal FDA employee, or was she still an ARPA-H detailee? What ethics screen was applied when a recent Arnold Ventures gene therapy policy author moved into CBER leadership? Was she involved in any rare disease or gene therapy meetings? And why is she staying at the FDA? insights.citeline.com/pink-sheet/adv… fas.org/wp-content/upl… goodscienceproject.org/about/michael-…

Rod Wong, MD@docrodwong

in addition to makary and prasad, without waiting for new leadership to decide, the administration went ahead and showed the rest of the leadership team associated with arnold ventures the door. this sends a strong message this administration is serious about innovation, cares about rare disease patients, and won't let american biotech lose its leadership position in the world.

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Peter Mantas@peter_mantas·4h

@stuartbuck1 @mike98572986 @CommonSense3241 @TinMarkProd @Tim_Corr Donanemab, Roctavian, Pirfenidone, Afrezza are all examples of drugs that met or beat P3 evidence yet were rejected initially for a whole host of reasons. There are many reasons why a drug is rejected despite strong p3 evidence.

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Stuart Buck@stuartbuck1·5h

@mike98572986 @CommonSense3241 @TinMarkProd @Tim_Corr It is a very simple question. Someone claimed that the FDA has been rejecting life saving therapies. I am asking for an example that has strong Phase 3 evidence.

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