Picazo Lab

I am looking forward to this year's ACS SD national meeting after populating my itinerary with many incredible talks! If you are around, then please consider attending some talks from the Picazo Lab! #ACSSpring2025 #ACS #ACSSD

We are thrilled to share our latest discovery nature.com/articles/s4200… ! Give this iron-catalyzed reaction a go if you need a benzylic or tertiary carbon–heteroatom bond! I can't wait to further apply it ourselves! Congrats to the team on filling some nice gaps in metal catalysis!

Compartmentalizing Donor–Acceptor Stenhouse Adducts for Structure–Property Relationship Analysis | Journal of the American Chemical Society @_Picazo @USCChemistry @USCChemistry #JACSPerspective Photoswitches Electronics Sterics Photophysical Properties pubs.acs.org/doi/10.1021/ja…

Donor-acceptor Stenhouse adduct (DASA) photoswitches are synthetically modular, leading to tunable photophysical and switching properties! To facilitate designer DASA construction, we describe compartmentalized DASA structure-property relationships! Read the Open Access @J_A_C_S Perspective here, pubs.acs.org/doi/10.1021/ja…

Fungibility isn't only for fiat vs #crypto (think #NFTs – how relevant with #BTC hitting ATHs)! "We recognized that the homodimer of a disulfide is the fungible disulfide itself and is, therefore, inconsequential to the transformation." We are grateful to Synlett / Synpacts for the opportunity to give more background on the design behind our recent iron-catalyzed cross-electrophile disulfide coupling! Read more here, thieme-connect.com/products/ejour…

Hi! We are excited to share that the newest Synform issue features our group's rearrangement and photoswitch chemistry! Learn more here, thieme-connect.com/products/ejour…

USC Chemistry graciously highlighted our newly discovered heterocyclic rearrangement and its application to create new chemical matter that responds to light! You can read more here, dornsife.usc.edu/chemistry/2024…

We’ve been enjoying great success at USC in the past couple of years and would love for you to pursue your PhD in chemistry with us!! Our application is now available! Please share with interested students and learn more here, dornsife.usc.edu/chemistry/grad…

Our future is bright

!! Our most recent publication is now at Nature Communications! We developed a pyrrole rearrangement and used it to create and study a new subclass of light-responsive small molecules named amino DASAs! Congratulations to the team!! Learn more here, nature.com/articles/s4146…

‼️ I am thrilled to share our newest preprint describing the use of iron for a metal catalyzed C(sp3)–halide coupling with soft thiol nucleophiles! We are inspired by advances in iron catalysis happening across the world! Read our preprint here: chemrxiv.org/engage/chemrxi…

🥳 Our group was recently honored with the President’s Sustainability Initiative Award!! We are excited to further our understanding of iron catalyzed reactions! Congratulations to the group!!

Also, congrats to Julius for being recognized for "Excellence in Graduate Student Research"!

This year's #USC Stauffer Lecture, featuring Prof Ben List, was awesome! The symposium had great talks by Profs Dong (UCI), Kwon (UCLA), Nelson (Caltech), Thompson (USC), Vanderwal (UCI), Wang (URI), and Williams (USC). It was an honor to present with such a lineup! 🤩 #FightOn

I like this pic better! It shows how nitrogen's additional bonding orbital enabled a rearrangement that had been limited to furans since 1850! It also highlights how amino DASAs unlock the final static compartment in DASA photoswitches! Read more here: chemrxiv.org/engage/chemrxi…

The Piancatelli and related rearrangements have been limited to furans since 1850. We developed the first pyrrole equivalent and used it to make new light-responsive matter!! Read about the first amino DASAs in our @ChemRxiv preprint here chemrxiv.org/engage/chemrxi…

Honored because USC Chemistry featured our recently published work! 😊 USC article: dornsife.usc.edu/chemistry/2024… JACS article: pubs.acs.org/doi/10.1021/ja…

Awesome! Our iron-catalyzed cross-electrophile coupling in @J_A_C_S is a Most Read Article. It is now also Open Access. Check it out here, pubs.acs.org/doi/10.1021/ja…

!! Our group's first publication is now available in the J. Am. Chem. Soc.! We developed a scalable, iron-catalyzed cross-electrophile coupling and used it in a number of applications! We sincerely thank reviewers for strengthening our report. Please join me in congratulating Julius (@Ju_Seme) and Yuanjie! Learn more here, pubs.acs.org/doi/10.1021/ja…

I am beyond thrilled to share our group's first independent contribution as a preprint. We discovered an iron-catalyzed cross-electrophile coupling and used it for disulfide bioconjugation, drug synthesis, and other applications! Find the preprint here: chemrxiv.org/engage/chemrxi…