R2D2 TB Network

Striving to address the critical unmet need for better TB diagnostics in order to close the “diagnostic gap” and improve patient and public health outcomes. Visit our site to learn more about our project: r2d2tbnetwork.org #TB #tuberculosis

R2D2 TB Network study out in NEJM! MiniDock MTB met WHO accuracy targets across 7 countries using sputum & tongue swabs, outperforming smear microscopy by 24+ points. Grateful to every team member who made this possible. nejm.org/doi/full/10.10… #EndTB #TBDiagnostics

Proud moment for the @R2D2_TBnetwork. WHO & GLI just released the TB Near Point-of-Care & Swab-Based Testing Toolkit, bringing molecular TB testing closer to where people seek care. R2D2 is proud to be among the technical contributors. stoptb.org/who-we-are/sto… #Tuberculosis #EndTB

🚨 At #UnionConf2025: “Transforming TB detection through tongue swab-based molecular testing” 🗓️ Nov 19 | 8–9AM | Copenhagen New tools beyond sputum → faster, affordable TB diagnosis. Details: unionconf2025.abstractserver.com/programme/#/de… #TB #GlobalHealth

Can a smartphone-recorded cough help detect #TB? 🫁 The CODA TB DREAM Challenge shows promise: AI + clinical data hit 73.8% specificity at 80% sensitivity across 7 countries. Read more: academic.oup.com/ofid/advance-a…

New Lancet study in Philippines, Vietnam, South Africa, Uganda & India: People tested for #TB prioritize diagnostics that are • Low-cost • Accurate • Deliver results in 15 minutes Findings show need to align WHO TPPs with patient preferences. thelancet.com/journals/lanpr…

New @cochranecollab reviews: combining TB tests for children and people living with HIV can boost sensitivity and could be beneficial in high burden settings, data for new #WHO recommendations Full reviews: bit.ly/45nlHCz and bit.ly/4laK2QH #TB #HIV #ChildHealth

Big news: @WHO approves 6 CAD tools for TB detection on chest X-rays—boosting case finding in high-burden settings. Proud that #R2D2_TBnetwork data contributed to the report. #EndTB #DigitalHealth #TBscreening #GlobalHealth createsend.com/t/d-F03FD74C15…

🎉 Congratulations to Dr. Yu on his election to the National Academy of Science and Technology, Philippines (NAST PHL)! A well-earned recognition—now honored with the prestigious title of Academician.

Our new multi-country study evaluates swab-based molecular tests for #TB, showing strong accuracy using both sputum and tongue swabs. Near point-of-care platforms like MTB Ultima and MiniDock MTB could help enable universal molecular testing. medrxiv.org/content/10.110…

In our study of 2,904 adults with #TB symptoms across five high TB-burden countries, CRP-based screening had 84% sensitivity and 61% specificity. Though CRP didn’t meet minimum diagnostic targets overall, its accuracy varied by setting and subgroup. atsjournals.org/doi/10.1164/rc…

New study: #TB screening in 5 countries ✅ CAD4TB outperforms Xpert HR & CRP at 90% sensitivity ✅ Combining tests boosts accuracy further Key progress for TB detection in high-burden areas! Read more: #TBResearch" target="_blank" rel="nofollow noopener">academic.oup.com/cid/article/do… #GlobalHealth

New Study: Preferences for TB preventive treatment in Uganda ✅ Top priorities for PLHIV: fewer pills, weekly dosing, no ART adjustments. 🔑 Simplified regimens = better uptake & adherence. Read more: onlinelibrary.wiley.com/share/WV29G79N… #TB #GlobalHealth

New #IHFBlog by Dr. Devan Jaganath on “Closing the Paediatric TB Diagnostic Gap.” With 1.3 million children under 14 affected by #Tuberculosis globally, and India accounting for 30% burden, urgent non-invasive #Diagnostics are needed. bit.ly/4eOODFl #IndiaHealthFund

Leveraging COVID-19 tests for TB diagnosis! We found 66 potential devices that could meet WHO's TB needs, including LumiraDx, Lucira, and Visby. A step toward better #TB testing. mdpi.com/2982512 #mdpijcm via @JCM_MDPI #TBdiagnostics

TB remains the top infectious killer, with survivors at risk of long-term health issues. Dr. Sophie Huddart @UCSF is using smartwatches to track TB patients' health during & after treatment. Pilot trial starts in Uganda. Learn more: globalhealthsciences.ucsf.edu/can-smartwatch… #EndTB #GlobalHealth

WHO releases updated guidelines on TB preventive treatment createsend.com/t/d-DBD9D64731…

WHO issues rapid communication on key updates to the treatment of drug-resistant #tuberculosis createsend.com/t/d-DBE0F2F1A6…

Call for expression of interest by manufacturers of software for computer-aided detection of #tuberculosis (CAD) to submit products for WHO expert assessment createsend.com/t/d-12D77291D0…

WHO releases updated Target Product Profiles for tuberculosis diagnosis and detection of drug resistance createsend.com/t/d-5DE2E47385…

🔬 New Study: Improving TB detection in high-burden countries with accessible, accurate tests. CAD4TB outperforms other tests, meeting WHO targets. Combining tests boosts accuracy. Read more: medrxiv.org/content/10.110… #TB