Steve Jackson Lab

Ever noticed that #CRISPR editing results differ between cells? Awesome PhD student @MSchlapansky developed "scOUT-seq" to measure single cell transcriptomes + editing. 1.2 million cells, 74 cell types, living 🐭. Cell subtypes differ wildly from bulk! biorxiv.org/content/10.110…

@jcornlab @MSchlapansky Congratulations Moritz

Congrats to @MSchlapansky, who successfully defended his PhD thesis on Friday! You can read his work on "scOUT-seq" profiling of single cell transcriptomes + editing outcomes in millions of cells and living mice at biorxiv.org/content/10.110…

Interested in a PhD tackling major challenges in radiobiology and radiation oncology? @CRUKCamRadNet, @RadNetCRUKGla, @RadNetCRUKCoL, @RadNetCRUKICRMH, @RadNetCRUKLeeds, @unibirmingham, @MCRCnews Apply for this unique PhD opportunity, bit.ly/4nIq4OR

Now out in @NatureComms, rdcu.be/eKaHC. Spearheaded by @jordancjwilson with Marciniak Lab @TheCIMR, @villunger, @ERC_Research partners @jcornlab & @LoizouJoanna & colleagues @BiffiGiulia @CRUK_CI, this work sheds light on WEE1 inhibitors and their therapeutic use.

The @SPJacksonGroup were very sad to hear the news of John's death. We were very privileged to work in the @GurdonInstitute for many years, benefitting from John's insight and wisdom. He inspired so many. We send our deepest condolences to his family and all who knew him.

Do you want to join the @SPJacksonGroup @CRUK_CI ?Don't miss this opportunity cruk.cam.ac.uk/vacancies/astr…

Professor Jason Carroll, Interim Director at the @CRUK_CI emphasised how this is affecting their research.

We're very proud of what we've achieved through our partnership with @AstraZeneca. We've made progress for patients, we've trained brilliant young scientists and we've helped to build a world-leading life sciences cluster. Here's to the next 10 years 🤝 cam.ac.uk/stories/astraz…

We are so excited to see this collaboration now published

Our Simon Lam developed the user-friendly web portal to freely share this map of interactions, spidrweb.org, making this a global resource for all, to help identify therapeutic targets for cancer and other DDR-related diseases.

Thrilled to see this “veritable tour de force” led by @John_C_Fielden from @jcornlab out @nature,rdcu.be/ehd4E. This @ERC_Research funded project uses #CRISPRi to systematically scan 548 DDR genes for synthetic lethal interactions, ~150,000 pairwise combinations!

Research Assistant (Jackson Group) (Fixed Term) @Cambridge_Uni jobs.cam.ac.uk/job/50998/

A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com

Exciting opportunity for @ASTARsg student @GangGoh to exchange new ideas on #CRISPR and #BaseEditing with @SPJacksonGroup members past @durocherlab, and present #CRISPR25 @eventsWCS

@jordancjwilson @TheCIMR @villunger @ERC_Research @jcornlab @LoizouJoanna We also acknowledge the partner publication from the Van Vugt Lab @researchumcg and @durocherlab, biorxiv.org/content/10.110…

Excited to share our preprint, work spearheaded by PhD student @jordancjwilson with Marciniak Lab @TheCIMR, @villunger & our @ERC_Research partners @jcornlab & @LoizouJoanna. This sheds light on the action of WEE1 inhibitors and their therapeutic use, bit.ly/4bDpxZl

Early bird registration deadline less than two months away. Check out this great line up @TheBACR 65th Anniversary Meeting.

Present your CRISPR research on a global stage!🧬✂️ Share your #GeneEditing insights with peers interested in learning more about applying #CRISPR approaches for modulating the genome at scale. #CRISPR25 ⏰Abstract deadline: 4 February 📎 Find out more: bit.ly/3Amz34N

Don't miss this opportunity to learn about #CRISPR from world experts including Thijn Brummelkamp @NKI_nl, @durocher1, @erika_alden_d, @LeopoldParts @sangerinstitute and Weixin Tang @UChiChemistry. Bursary application deadline 14 Jan, abstract deadline 4 Feb. Tell your friends!

This exciting novel discovery, published in @NatureComms, with contributions from the Balasubramanian lab @ChemCambridge, was supported by @CR_UK, @TheMarkFdn, @wellcometrust and @ERC_Research.