Sebastian Bitzenhofer

(1/8) My latest study is out in @Nature ! Kudos to coauthors especially @jess_cardin and to @KavliAtYale and @WuTsaiYale for support. We find that gamma power in mouse visual cortex is caused by brief events supporting visual processing #Ack1" target="_blank" rel="nofollow noopener">nature.com/articles/s4158…

New preprint from @HanganuOpatzLab! We present iSTTC, a robust method for estimating intrinsic neural timescales (ITs) from single-unit activity. It’s accurate, stable, and works even when data is sparse. doi.org/10.1101/2025.0…

#JNeurosci | Parbst, Kostka, et al. found a new link between how the sense of smell and cognitive abilities develop in mice. vist.ly/3n52e67

Dendritic Integration Symposium next Tuesday Dec 10th. Online. Free. Great speakers !

Excited to uncover the mechanistic basis of feedback-driven computations in the cortex, inspired by connectomic and functional data supported by an ERC Consolidator Grant #ERCCoG. Thank you for the support @ERC_Research

Ever wanted to explore the driving forces underlying inhibitory neuronal signalling? We did! So, for my MSc in @JosephRaimondo lab, we developed the all-optical approach ORCHID - all-Optical Reporting of CHloride Ion Driving force. Now out in @NatureComms nature.com/articles/s4146…

New high-def EMG tools from CAMBER on display at #SfN2024! Visit 𝐁𝐨𝐨𝐭𝐡 𝟏𝟖𝟔𝟗 to see 👉New array designs for 🦗🐭🐀🐦🐒🚶+ 👉Opto-myomatrix: EMG + μLED for recording + optical stim of muscles, nerves, and sensory cells elifesciences.org/articles/88551 biorxiv.org/content/10.110…

It is out! Huge shoutout to Helene, very talented MD student. Many thanks to our collaborators from @IPB_Halle. We developed a simple assay to screen for a natural substance preventing the astrocytic uptake of amyloid to avoid neurotoxic signaling. link.springer.com/article/10.100…

Excited to announce that I've started a regular column at The Transmitter @_TheTransmitter ! First column just out on that most convenient of all the fictions in neuroscience: averaging thetransmitter.org/neural-coding/…

Does large-scale neural MEG activity correlate with micro-scale circuit properties? Our new work shows that aperiodic background activity indexes neural hyperexcitability in patients suffering from generalized epilepsy in @SfNJournals: eneuro.org/content/11/9/E… (1/4)

So honored to receive the Adolf Fick-Award! It is the prize for all the past and present members of the lab, our "hall of fame". Grateful for the kind laudatio by my mentor Andreas Draguhn @DraguhnLab

Check out this @biorxivpreprint from our lab, led by @annaostenrath, on the role of glutamate-driven inhibition in neural circuit connectivity, sensory computations, and adaptive behaviors. biorxiv.org/content/10.110…

My #AI4Neuro magnum opus: Discovery of spiking network model parameters constrained by neural recordings, using simulation-based inference & generative “AI”. (aka the answer to “how the f did you end up in Tübingen?”) Here's what we have in store: biorxiv.org/content/10.110…

Recruiting postdocs! Please get in touch if you wanna discuss projects on biologically plausible learning through TUM's global postdoctoral fellowship tum.de/en/about-tum/c…

Our lab at @UKEHamburg is recruiting! We are looking for a highly motivated PhD student to study the circuit dynamics underlying the development of cognitive flexibility. Please RT

Upcoming online symposium on "Dendritic Integration", Tuesday December 10th, 11:00 am - 4:00 pm EST. Great speakers and free registration! ntc.columbia.edu/dendritic-inte…

Where in the brain is abstract map generated? It is the lateral entorhinal cortex (LEC) and the medial prefrontal cortex (mPFC), working together!! Here is our new finding published in @Nature Prefrontal and lateral entorhinal neurons co-dependently learn item–outcome rules Heechul Jun†, Jason Y. Lee†, Nicholas R. Bleza, Ayana Ichii, Jordan D. Donohue & Kei M. Igarashi* Nature (2024) nature.com/articles/s4158… When you learn new items, your learned knowledge is sorted into an “internal map” of the brain. An internal map, also called as an “abstract map”, is made of population activity of many neurons. In this new work led by Heechul Jun @jun_heechul and Jason Lee @jasonyensunlee, we found that the LEC deep layers and mPFC co-dependently generate abstract map during learning. These two areas had bidiretional anatomical connections, making a loop circuit. Inhibition of the LEC disrupted the abstract map in the mPFC, and mPFC inhibition deleted LEC abstract map. Our message is: LEC and mPFC are best friends! @AnatomyNeurobio @UCIMedSchool @uci_bme @UCIEngineering @UCI_NeurCircuit @ucicnlm @ucimind @UCIrvineNews @UCIrvine

How can memories persist in the brain when their properties and supporting biological substrates change over time and experiences? Our latest work newly published in @ScienceMagazine proposes that a balance between memory dynamics and persistence is achieved through the divergent recruitment of multiple memory traces established in parallel upon memory encoding. science.org/doi/10.1126/sc… Welcome to the Multiverse of Memory! A thread. 1/7

We're recruiting! The Wachowiak lab at @UtahNeurosci has postdoctoral positions available. Interested in odor coding, neural dynamics, active sensing, in vivo imaging/ephys? Check us out! Please RT. wachowiaklab.org #ScienceJobs #Neuroscience

🚨Postdoc opening in the lab!!! If you are interested in dissecting the peripheral and spinal circuits involved in chemotherapy-induced neuropathy, email me your CV, cover letter, and references as one pdf file. Deadline 31 August 2024!