Stacy Malaker

Five years ago, I shared a picture of CRB on my very first day at @YaleChem. Today, almost exactly 5 years later I'm walking into the same building with a new title (and a lot of construction)! I’m thrilled to share that I am officially an Associate Professor with tenure!! 🥂🎉

Yale chemists have developed a new digital framework they say will speed up drug discovery and other breakthroughs. MOSIAC is an open-source AI-guide for researchers navigating the complex world of chemical synthesis. Learn more in this article bit.ly/3Zrnv9j.

@vchangchemistry As always, we welcome feedback and discussion! 👏 👏Huge congrats to the outstanding team who made this possible. #glyotime #TeamMassSpec #peptidomics #preprint

@vchangchemistry While the tear film provides a uniquely accessible and glycan-rich model system, the principles we uncover are broadly relevant to glycopeptide chemistry, protease specificity, and the design of peptide-based therapeutics.

More good news from me this week: another Malaker lab preprint!! 🚀🚀Headed up by outstanding graduate students @vchangchemistry and Ryan Chen, they decided to take a peek 👀 (pun intended) at the native tear fluid (glyco)peptidome 🥲🥲: doi.org/10.26434/chemr…

@NaOHBartfield Thanks Noah!!

🚨🚨🚨Tenure Alert 🚨🚨🚨 👇👇👇

@YaleChem Today, I feel just as excited about the science, even more grateful for the people, and energized for what comes next. I’m SO proud of what we’ve built together and excited for the #glycotime #TeamMassSpec #mucinomics future ahead. Cheers to the next chapter! 🥂🥂🥂

@YaleChem I also have to thank my family, my friends, and my amazing fiancé who all support me immensely behind the scenes. I love you ♥️!!

Five years ago, I shared a picture of CRB on my very first day at @YaleChem. Today, almost exactly 5 years later I'm walking into the same building with a new title (and a lot of construction)! I’m thrilled to share that I am officially an Associate Professor with tenure!! 🥂🎉

@vchangchemistry I’m incredibly proud of the team, especially @vchangchemistry for pushing glycoproteomics to address such complex biological questions. Tear fluid still has so many glycobiology secrets left to uncover... and we’re just getting started! Stay tuned for more updates to come! 😇 😆

@vchangchemistry This work opens the door to understanding how glycans, splicing, and protein assembly cooperatively shape immune and barrier function at the ocular surface. We envision this could help guide future therapeutic strategies in conditions like DED, where Gal-3 levels are dysregulated

Some light holiday reading for everyone!! 🎉 🎊 I’m thrilled to share our newest preprint investigating galectin-3 biology in tear fluid 👀, led by rock star graduate student @vchangchemistry !! biorxiv.org/content/10.110…