Willsey Lab

Congrats @ShengWangD on your recently published work, which establishes a clear contribution of rare variants on Chromosome X to male-biased psychiatric disorders and identifies a new X-linked high confidence autism gene, MAGEC3. linkedin.com/posts/jeremy-w…

New UCSF-led research reveals the complex interplay of #genetic factors contributing to male-biased prevalence in #autism spectrum disorder, #Tourette syndrome, and #ADHD, paving the way for future advancements in #neurodevelopmental disorder research. nature.com/articles/s4146…

And as always, this work would not have been possible without all of the patients and their families that so generously participated in this research #Autism #tourette #ADHD @UCSFPsychiatry @SFARIorg @Spectrum @TouretteAssn @CHADD_ADHD

Congrats @ShengWangD on your recently published work, which establishes a clear contribution of rare variants on Chromosome X to male-biased psychiatric disorders and identifies a new X-linked high confidence autism gene, MAGEC3. linkedin.com/posts/jeremy-w…

Thanks to everyone in the @WillseyLab, especially @belinda_p_wang and @snw555, as well as our fantastic collaborators, including Vanessa H. Bal, Gary Heiman, Jay Tischfield, Thomas Fernandez, and Matthew State.

Excited about our new pre-print - investigating the impact of autism-linked genes on neuronal differentiation. biorxiv.org/content/10.110… Co-led by @WillseyLab @snw555 and @KampmannLab @noamteyssier & @RuilinSUSTech. Read Noam's tweetorial here:

Very excited to present our recent preprint! This was a massive effort over the past three years that investigates the complex biology of high-confidence ASD (hcASD) genes during early timestamps of neurogenesis using single-cell CRISPRi. biorxiv.org/content/10.110…

Congrats Nawei and Noam for conducting the largest CRISPR-based screen of high confidence autism risk genes conducted to date. Follow the link for more details! @snw555 @noamteyssier @belinda_p_wang @fimazaltsman @MartinUCSF @UCSF @Spectrum @SFARIorg linkedin.com/posts/jeremy-w…

Thanks to our many collaborators, especially Matthew State @rhuttenhain , @LabNowakowski , @goodfrognosis , and the rest of the @pcmi

Congrats @belinda_p_wang , Rasika, @fimazaltsman , @SnowNaing1 and the rest of the team for creating a comprehensive map of the protein-protein interactions of 100 high confidence autism genes @WillseyLab @KroganLab @UCSFPsychiatry @Spectrum @SFARIorg linkedin.com/posts/jeremy-w…

Jeremy Willsey, PhD, highlights the potential of targeting interacting proteins, opening doors to treatments benefiting larger groups of autism spectrum disorders patients. A step towards more effective clinical trials. psychiatry.ucsf.edu/news/how-prote…

Check out our new preprint quantifying the contribution of rare X-linked genetic variation to three male biased neurodevelopmental conditions: autism, Tourette syndrome, and ADHD medrxiv.org/content/10.110… @UCSFPsychiatry @QBI_UCSF @PsychCellMap @ucsfrrtp @SFARIorg @spectrumnewsorg

Recent studies, by @goodfrognosis, A. Jeremy Willsey, @belinda_p_wang & Matthew W. State, have gained insights on compounding genetic risks for autism spectrum disorder and are closer to developing therapeutical interventions. @WillseyLab 🧬ucsfpsy.ch/3vANFs8🧬

@RMeyerSchuman Thank you!

Excellent review!

@WalentekLab @NatRevNeurosci @goodfrognosis @belinda_p_wang @UCSFPsychiatry @QBI_UCSF @PsychCellMap Thanks Peter, hope you are doing well! We think of you often.

@WillseyLab @NatRevNeurosci @goodfrognosis @belinda_p_wang @UCSFPsychiatry @QBI_UCSF @PsychCellMap Congratulations that's fantastic, need to read 😀

Proud to have our review paper published online today in @NatRevNeurosci Also feel very fortunate to have such wonderful co-authors in @goodfrognosis @belinda_p_wang and Matt State @UCSFPsychiatry @QBI_UCSF @PsychCellMap nature.com/articles/s4158…

Studies have identified a growing list of associated risk factors for autism, and—with the use of gene editing tools, multidimensional omics datasets, and higher-throughput model systems—possible therapies. @goodfrognosis @belinda_p_wang @WillseyLab 🧬ucsfpsy.ch/3MkLTkq🧬

Genomics, convergent neuroscience and progress in understanding autism spectrum disorder – a new Review by Helen Rankin Willsey, A. Jeremy Willsey, Belinda Wang & Matthew W. State @goodfrognosis @belinda_p_wang @WillseyLab @UCSFPsychiatry @UCSF go.nature.com/3EKAUOR

And special thanks to @ShengWangD for his tireless work in creating and revising Figure 1!