Prashant Bhat

267 posts

Prashant Bhat banner
Prashant Bhat

Prashant Bhat

@_prashantbhat

Foraging unknown molecular and cell biology to improve human health M.D. @UCLA👨🏽‍⚕️Ph.D. '23 @Caltech Incoming Pathology Resident @UCSFPath

Pasadena and Los Angeles, CA Katılım Kasım 2017
768 Takip Edilen901 Takipçiler
Sabitlenmiş Tweet
Prashant Bhat
Prashant Bhat@_prashantbhat·
A long sought after hypothesis has been that organizing biomolecules in and around nuclear bodies is essential for functional RNA processing. We now provide direct evidence of this in @Nature for nuclear speckles and mRNA splicing. Check out this thread! nature.com/articles/s4158…
Mitch Guttman@mitchguttman

What are the functional roles of 3D genome organization? Our paper in @Nature led by @_prashantbhat demonstrates how dynamic 3D genome organization around nuclear speckles plays a crucial role in regulating mRNA splicing efficiency. rdcu.be/dHkez

English
14
27
154
40.1K
Prashant Bhat
Prashant Bhat@_prashantbhat·
4/2015: First day visiting Caltech 4/2026: Same spot, last day in Pasadena 11 years later! Kudos to my mom for remembering this picture and wanting to recreate it. Moms know best :) Also, she wants you to know she didn't age. @uclacaltechmstp @Caltech @CaltechBBE
Prashant Bhat tweet media
English
4
1
61
5.7K
Stirling Churchman
Stirling Churchman@fiddle·
@_prashantbhat @openclaw It is! I run the Mac Mini headless so it's always on and has a small footprint. I got just the basic model (M4) because I'm not running AI models locally. I'm using @OpenAI models for now.
English
1
0
3
301
Stirling Churchman
Stirling Churchman@fiddle·
It was my birthday a couple of weeks ago so I bought myself a Mac mini and installed @openclaw Meet Tessera! If you’re wondering what a “normie” genetics professor is doing with it or want tips to get started, ask 👇 !
Stirling Churchman tweet media
English
14
7
182
24.7K
Prashant Bhat retweetledi
Mitch Guttman
Mitch Guttman@mitchguttman·
Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @CellCellPress, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. sciencedirect.com/science/articl…
Mitch Guttman tweet media
English
9
114
397
37.1K
Prashant Bhat retweetledi
brangwynnelab
brangwynnelab@brangwynnelab·
Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of @sofiquinodoz & @jiang_lifei w/ @LafontaineLab & Sebastian Klinge and other fantastic co-authors nature.com/articles/s4158…
Sofi Quinodoz@sofiquinodoz

Excited to share a new preprint! (1)🔬The nucleolus is the most prominent nuclear condensate, with a fascinating multilayered liquid-like structure, and is the site of ribosome biogenesis. But how does this multiphase architecture form and function? biorxiv.org/content/10.110…

English
3
37
144
12.8K
Prashant Bhat retweetledi
Yodai Takei
Yodai Takei@yodai_takei·
Excited to share our new paper out in @Nature revealing cell-type specific nuclear organization and its link to gene regulation using new spatial multi-omics technologies! nature.com/articles/s4158…
English
5
54
273
29.1K
Prashant Bhat
Prashant Bhat@_prashantbhat·
@shae_mcl Cool! Can’t wait to dive in. Does filtering for genomic regions by expression influence the predictions?
English
1
0
0
237
Shae McLaughlin
Shae McLaughlin@shae_mcl·
A small slice of what I've been working on 🙂 Getting transformers to learn sequence determinants of genome architecture—we pre-trained a decoder-only model on eukaryote genomes and fine-tuned on nuclear lamina and nuclear speckle association. biorxiv.org/content/10.110…
English
3
8
38
6.6K
Prashant Bhat retweetledi
Mitch Guttman
Mitch Guttman@mitchguttman·
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in @NatureGenet describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. nature.com/articles/s4158…
English
8
189
680
57.9K
Ayush Noori
Ayush Noori@ayushnoori·
We’re excited to host @_prashantbhat from @uclacaltechmstp at the @HarvardDBMI Trainee Seminar Series (TSS) in the first week of December. Please see RSVP link below and feel free to reach out if any questions. 👇🏽
Prashant Bhat@_prashantbhat

Hi! I’ll be speaking at @harvardmed Department of Biomedical Informatics on December 5th about genome organization and splicing/speckles. Thank you to the organizers for the invite! Harvard/MIT/affiliate trainees can RSVP to attend with this link: forms.gle/LopwGCc8RbuCqS…

English
1
1
5
880
Prashant Bhat
Prashant Bhat@_prashantbhat·
Hi! I’ll be speaking at @harvardmed Department of Biomedical Informatics on December 5th about genome organization and splicing/speckles. Thank you to the organizers for the invite! Harvard/MIT/affiliate trainees can RSVP to attend with this link: forms.gle/LopwGCc8RbuCqS…
Prashant Bhat tweet media
English
2
16
91
13.8K
Levi Palmer
Levi Palmer@inelasticlevi·
@doescience This month has been a whirlwind 🌪️ of both amazing and terrible emotions for me ... BUT I'm happy to share our new preprint on an #EELS thermometry technique we're developing :,) arxiv.org/abs/2411.01071
English
1
0
3
203

Keşfet

@uclacaltechmstp @Caltech @CaltechBBE @cavankatenaugh @UCSFPath @mitchguttman @UCLA_Pathology @bloodgenes