Andrés López Perrote

Link to the paper: cell.com/structure/full…

Our take on the struture of the R2T complex 🌱 Now out in @Structure_CP! A fun collab led by @alopezperrote and the @AlabadiDavid lab at @IBMCP . Check it out in the next post 👇

Hi, we have published a study in @Structure_CP that you may like it! This work is the result of a fantastic collaboration between our group @IBMCP and @LlorcaLab (@CNIOStopCancer), aimed at understanding the role of the HSP90 cochaperone R2T in plants doi.org/10.1016/j.str.… 👇

Online now! The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP dlvr.it/TJC8Zg

The γTuRC saga goes on! This time, we used cryoEM to describe how CDK5RAP2 helps nucleating microtubules by activating the γTuRC nucleator. Another tour de force led by @sernarina and Fabian Zimmermann and a fun collab with @LudersLab @IRBBarcelona. authors.elsevier.com/c/1jpyq_Yv6zvB…

And a movie with those beautiful high-res densities 🤓

Thrilled to share our last work @CellRepPhysSci Revealing the molecular mechanism of an anti-tumoral compound inhibiting our favourite system, RUVBL1/2 (at 2.4 Å resolution)🔥 All-@LlorcaLab work led by @CarmenBePaper and @alopezperrote Link below 👇 doi.org/10.1016/j.xcrp…

And also... 🔥pre-print alert🔥 We take a look at our favourite system in plants🌱, the R2T complex, an HSP90 co-chaperone. A study led by @alopezperrote (@CNIOStopCancer) and Alberto Palacios (from @AlabadiDavid's lab at @IBMCP). Check it out 👇 biorxiv.org/content/10.110…

Big congratulations to our new #CNIOStopCancer PhD Dr. Natalia Cuervo Iturrioz! 🎉 👉#CNIOPhDThesis: 'Human WAC is a partner of chaperone complexes involved in the assembly and activation of mTORC1'. Exciting times are ahead! 👏 🎓Directors: @OscarLlorcaCNIO and @sernarina.

PAPER ALERT🔥 We took a deep dive into the microtubule 🔍 using cryoEM ❄️🔬to capture the earliest steps of nucleation by the γTuRC complex. With @sernarina and @DeBritoClaudia leading the way. Proud of our collab with the @surrey_lab at the @CRGenomica ! science.org/doi/10.1126/sc…

@merypierce @Renfe Ahora ya parece funcionar el link a este abono. Gracias

@Renfe @alopezperrote Sigue apareciendo error y no hay opción de compra

📢 ¡No lo dejes para última hora! Adquiere ya el abono gratuito de Cercanías, Rodalies y Media Distancia para el segundo cuatrimestre de 2023, del 1 de mayo al 31 de agosto. Más info 👉 bit.ly/42Sdnae

Thanks to #CNIOStopCancer colleagues for these two days of retreat full of ideas and inspiring talks. Shared time makes stronger teams!! 😃

📸Hoy hemos mantenido una reunión de seguimiento del consorcio que coordina nuestra investigadora @MaiteHuarteLab, en el que participan @CNIOStopCancer y @CNB_CSIC 🔝Proyecto que busca nuevos tratamientos para el cáncer colorrectal financiado por #CaixaResearchFundlaCaixa

Great meeting @CIMA_unav together with @LlorcaLab and @MaiteHuarteLab in the context of our @CaixaResearch project! Thank you Maite for hosting us!!

Great @Tec4Bio meeting with all our members and finally in person!🎉 @FMorenoHerrero @AlegreCebollada @madelpozo67 @OscarLlorcaCNIO Ricardo Garcia @icmmcsic and Gustavo Plaza @La_UPM Thanks to @XavierTrepat and @RuedaLab for taking part in it. Looking forward the next one.

Just out! RUVBL1/2 strikes back, this time together with ZNHIT2, a complex involved in the maturation of PRPF8. The great @sernarina, @AnaCorpalez, Sofía Cabezudo and @alopezperrote spearheading this project. Full text link below 👇

@Renfe Alguna previsión de si sl servicio Toledo-Madrid será restablecido para mañana?

Consulta aquí la información relativa a la situación de los trenes afectados por el temporal de lluvia 👇 renfe.com/es/es/avisos/t…

@Inforenfe Alguna idea de cuándo se restablecerá Toledo-Madrid?

12:00 INFO AFECTACIÓN LLUVIAS: Línea Madrid-Cuenca: Restablecida la circulación. Linea Madrid-Toledo: Circulación suspendida. PAT por carretera entre Villareal de Huerva y Zaragoza: Afectados MD: 18502, 18515, 18506,18517.

@illodani @Adif_es @InfoAdif @Inforenfe 🙋🏼‍♂️

Hemos movilizado los recursos necesarios para restablecer el servicio lo antes posible en los puntos afectados por la DANA ℹ️ @InfoAdif @inforenfe #App de Adif bit.ly/38v8AR1 📸Os dejamos algunas imágenes de las consecuencias de las tormentas sobre la infraestructura