Ben Fidler

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Ben Fidler

Ben Fidler

@BentheFidler

Biotech Journalist; Lead Editor, BioPharma Dive. Former Deputy Biotech Editor, Xconomy.

Virginia Katılım Nisan 2013
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Ben Fidler
Ben Fidler@BentheFidler·
New: Here’s our latest primer on 10 of the top clinical trials to watch in #biotech over the next 6 months, and why you should keep an eye on them:  biopharmadive.com/news/biotech-p… $XBI $IBB
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John Maraganore 🇺🇸🇬🇷🇺🇦
1. RNAi is not ASO 2. TTR Kd with Vutri > Eplon… Nucre>>Eplon 3. HR for Taf + Vutri vs. Taf is 0.66 in HELIOS-B 4. HR for Taf + Eplon vs. Taf is likely >1.0 (!!) in CardioTTRansform (inferred based on 0.71 monotherapy HR and 81% of patients on stabilizer)… ASO creating harm?
Ronald Witteles@Ron_Witteles

The main issue: Stabilizers are really good therapies! We have not known the clear answer to the 'combination therapy' question despite a favorable signal with tafamidis +/- vutrisiran in HELIOS-B (mortality curves shown below).

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