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Beta is LIVE!

@ummuhub The future of women's health is here 👏🔥

Introducing Melody Maker, our creative director! Two years. Quietly building. Today we open the doors. UmmuHub is the first platform built entirely on female biology. Not adapted from male data. Not generalised. Built from scratch, on women, for women. We're not doing a big launch. We want 1,000 women in with us first. To use it, shape it, and help us build it into what it needs to be over the next 3 months. If you've ever been told your symptoms are normal when something felt wrong, this was built for you. 1,000 spaces only. Founding members get 30% off for life. Use code BETA30 at checkout. ummuhub.com Come build something that should have existed a long time ago. --- \#UmmuHub #FemTech #WomensHealth #Epigenetics #KnowYourBiology #FoundingMember #BetaLaunch #FemaleHealth #BiologicalAge #WomensWellness

@DEPHNetwork Exciting times 😎🔥 Lets goooo

Sunday energy 🔥 Tomorrow, the Ummu beta officially goes live. A new chapter for women’s health powered by epigenetics, biological data and real science. Built exclusively around female biology to deliver personalised insights, protocols and health optimisation at an entirely different level. The team has spent months building quietly behind the scenes. Tomorrow, the doors finally open. And this is only the beginning. ENGNE is close as well. Our male epigenetic performance platform is entering the final stages and looking stronger every day 👀 What is being built inside the DEPH ecosystem right now is unlike anything else in this space. @ummuhub #ENGNE #DEPH #EPIGENETICS #BIOLAYER

@ummuhub Awesome 👏🔥

The shop is LIVE, finally! I don't think you understand how long this has taken. Two years. 8,436 women in the study. A team that has given everything to build something that has never existed before. The world's first DNA and epigenetic test built entirely on women's data. Not borrowed from male research. Not averaged. Built from scratch for female biology. As of right now you can order it. 30% off for the first 1,000 women. Locked in forever. Discount code: BETA30 If you've spent years being told everything looks normal when your body was clearly telling you something different, then @ummuhub is for you! ummuhub.com

@DEPHNetwork @Marso2321

The DEPH community keeps growing 🧬💜 Want to stay close to the ecosystem, updates, AMAs, and the community building behind the scenes? Join our Telegram group here 👇 t.me/+6iEZMR7WmGYzY… See you there.

When we started building this, the vision was huge. Honestly, almost too huge. A health data network. Epigenetic science. Biological age testing. Women’s health. Men’s performance. AI coaching. Clinical partnerships. Elite sport. Medical cannabis. Global expansion. Most people told us the same thing: “Focus on one thing.” “Pick a lane.” “It’s too ambitious.” We didn’t pick one. We built an ecosystem.

Demo @ummuhub app with our CTO Aaron Hudson.

@wodonayo @DEPHNetwork @Muhdohealth @ummuhub $DEPH

$BIO Protocol vs $DEPH Network @DEPHNetwork @Muhdohealth @ummuhub 🧬 BIO Protocol: The DeSci Giant Already in Motion 🚀 DEPH Network: The Under-the-Radar Asymmetric Play

@DEPHNetwork @ummuhub

Hey everyone! Going live in 15 minutes to demo the new @ummuhub app with our CTO Aaron Hudson! If you want to check it out, please join! Ummuhub APP - DEMO Wednesday, 29 April · 6:00 – 8:00pm Time zone: Europe/London Google Meet joining info Video call link: meet.google.com/zqz-syrs-zvg

@ummuhub Really awesome stuff 👏 This is the future of healthcare.

Don’t ask the internet. Ask you. UmmuAI gives you answers based on your genetics and lifestyle data. Your body, not someone else’s. Real insight. Personal guidance. No guesswork. Built by experts.

Want to slow down aging at the cellular level? New research from the UmmuHub team (SportRxiv) reveals: Women who strength train for 12+ months have significantly younger biological age which is measured by lower DNA methylation on the female-specific UmmuAge clock. Lifters: ~0.5 years younger Non-lifters: ~2.5 years older Even after adjusting for real age, the effect holds strong.Strength training isn’t just about muscle — it’s about longevity, metabolism, hormones, and aging better from the inside out.Lift weights. Build muscle. Defy time. Source: sportrxiv.org/index.php/serv…

Big finding from our latest peer-reviewed publication in JARSIA: For the first time ever, our DEPH team have discovered that: Long-term creatine use isn’t just performance support, it’s linked to measurable changes in gene regulation. They found key signals: •⁠ ⁠64 epigenetic changes across 34 genes tied to performance •⁠ ⁠Activation of pathways linked to muscle growth, blood flow, and energy metabolism •⁠ ⁠Suppression of pathways associated with fatigue and growth inhibition •⁠ ⁠Signals pointing to improved recovery, vascularisation, and metabolic efficiency This showed that creatine may help shape a more “performance-ready” biological profile over time, not just acute output. The DEPH team are developing gene altering supplements opening a whole new market for existing supplements to be repurposed for chronic usage and long term gene expression change. Source: COLLINS, Christopher; PURAS, Arturas. Epigenetic Markers of Enhanced Athletic Performance Associated with Creatine Monohydrate Supplementation. Journal of Advanced Research in Sports: Interdisciplinary Approach, [S.l.], v. 1, n. 1, p. 5 - 13, mar. 2026

April is 𝐈𝐁𝐒 𝐀𝐰𝐚𝐫𝐞𝐧𝐞𝐬𝐬 𝐌𝐨𝐧𝐭𝐡. This chronic gut condition, marked by pain and bloating, is a puzzle of bacterial, environmental, and stress factors. But what about the genetic and epigenetic link?🧬 By examining genotypes, DNA methylation, and lifestyle data, we have uncovered a new layer of the IBS story. 𝐓𝐡𝐞 𝐊𝐞𝐲 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐅𝐢𝐧𝐝𝐢𝐧𝐠𝐬: 1. 𝐈𝐁𝐒 & 𝐋𝐨𝐧𝐠𝐞𝐯𝐢𝐭𝐲: Surprisingly, IBS appears to cause no significant alteration in biological ageing. It is a condition that impacts the quality of life, not the quantity. ☠️ 2. 𝐓𝐡𝐞 𝐈𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐋𝐨𝐨𝐩: Sufferers showed unhealthy methylation on specific inflammation-causing genes. We are investigating whether IBS causes this methylation, or if this epigenetics profile is what causes IBS. 🔥 3. 𝐆𝐞𝐧𝐞𝐭𝐢𝐜 𝐒𝐮𝐬𝐜𝐞𝐩𝐭𝐢𝐛𝐢𝐥𝐢𝐭𝐲: Those with IBS showed increased mutations in the TNF, CD53, FOXY3, and COMT genes.🧬 4. 𝐓𝐡𝐞 𝐋𝐚𝐜𝐭𝐨𝐬𝐞 𝐓𝐫𝐢𝐠𝐠𝐞𝐫: A massive 94% of the IBS group possessed a mutated MCM6 gene, which is directly linked to progressive lactose intolerance. 🥛 5. 𝐂𝐞𝐥𝐢𝐚𝐜 & 𝐖𝐡𝐞𝐚𝐭 𝐋𝐢𝐧𝐤: Nearly all participants carried the HLA-DQ2 and DQ8 haplotypes, which are highly associated with celiac disease.🍞 6. 𝐓𝐡𝐞 𝐋𝐢𝐟𝐞𝐬𝐭𝐲𝐥𝐞 𝐂𝐨𝐧𝐧𝐞𝐜𝐭𝐢𝐨𝐧: Both high stress levels and sleeping less than 8 hours a night were significantly overrepresented in the IBS cohort.😴 𝐖𝐡𝐚𝐭 𝐜𝐚𝐧 𝐡𝐞𝐥𝐩? 𝐄𝐩𝐢𝐠𝐞𝐧𝐞𝐭𝐢𝐜 𝐒𝐮𝐩𝐩𝐨𝐫𝐭: High-quality Curcumin (Turmeric) may act directly on the genes showing unhealthy methylation, though dosage is key to avoid symptoms. 𝐂𝐚𝐥𝐦𝐢𝐧𝐠 𝐭𝐡𝐞 𝐆𝐮𝐭-𝐁𝐫𝐚𝐢𝐧 𝐀𝐱𝐨𝐧: Relaxation techniques like meditation and yoga are proven to help. 𝐓𝐚𝐫𝐠𝐞𝐭𝐞𝐝 𝐍𝐮𝐭𝐫𝐢𝐭𝐢𝐨𝐧: Reducing lactose and implementing a food diary (focusing on gluten) is essential. For those with specific TNF mutations, a high glutamine intake (10-15g) can be beneficial. 𝐓𝐡𝐞 𝐒𝐥𝐞𝐞𝐩 𝐑𝐮𝐥𝐞: Rule: Sleeping less than 6 hours increases inflammatory gene expression (cytokine response). Prioritising 8 hours of quality sleep is a foundation of management. This research is just the beginning!! Our ongoing studies into DNA methylation are moving beyond symptom management and toward a future where we can predict, track, and ultimately outsmart chronic gut conditions. Better Gut Health. Back by science .🧬 #muhdo #IBS #genetics #nutrigenetics #epigenetics #guthealth #IBS

@ummuhub We need more focus on what’s happening before things show up in bloods 👌💯 Epigenetics is the future 👏

Your body whispers long before it shouts. We know how frustrating it is: you get your blood results back marked “normal,” yet you still don’t feel right. You’re not imagining things. For years, standard tests have only captured problems once they’re already circulating in your bloodstream. Epigenetics changes that. It reveals the upstream signals your cells have been sending long before anything shows up in routine labs. At UMMUHUB, we help you translate those early cellular signals. You deserve to protect your health BEFORE it fades. Let's listen together. 🤍 #UMMUHUB