CDN | King's College

Congratulations to @RNA_Richard for being awarded the Race Against Dementia Fellowship 👏 🔗 Read more about the prestigious 5-year award and Richard's research into synapse resilience and neuroprotective mechanisms in healthy ageing and dementia: tinyurl.com/2s39mcma

Dr. Katie Long is leading vital research, funded by an MRF award, to learn how pregnant people feel about vaccines during pregnancy. We want your views! Take this short survey:: tinyurl.com/vaccines-in-pr… For more information on vaccines in pregnancy visit tommys.org/vaccinations-p…

We're #hiring! Looking for an experienced and dynamic Research Strategy Manager... More details in link below Deadline 09 July kcl.ac.uk/jobs/118025-re…

We're #hiring for a new role as Senior EA to our wonderful Director and Managing Director! Deadline 23 June kcl.ac.uk/jobs/116505-se…

New paper from Julie Jézéquel and the @Rico_lab on role of cadherins in neuronal inhibition out now in @NatureComms! rdcu.be/el18f

I am hiring!! Please share in your networks. Deadline to apply: 26th May 2025 kcl.ac.uk/jobs/114685-re…

7/10 For PV interneurons, Vgf is the critical gene modulating the plasticity of inhibitory inputs received from other PV interneurons

4/10 Using experimental manipulations, we found that PV interneurons scale the inhibition they receive to maintain stability. When the activity of a PV interneuron increases, it “requests” more inhibitory inputs from other PV+ interneurons, effectively rebalancing its activity

3/10 Neuronal activity operates within a tightly controlled range for the optimal functioning of #brain circuits. When synaptic connectivity and network activity are modified, such as when we are learning, compensatory mechanisms are needed to maintain stability

5/10 How is this achieved? We found that PV interneurons induce the expression of two genes encoding multiple neuropeptides, Scg2 and Vgf, in response to increased activity

2/10 The cortex contains two main classes of neurons: excitatory “go” pyramidal cells and inhibitory “no-go” #interneurons

10/10 Here’s the paper @Nature if you want to dig in nature.com/articles/s4158… That’s it. Thanks for sharing! @dev_neuro @MRC_CNDD @KingsIoPPN @ERC_Research

9/10 In sum, our findings identify a previously unknown form of interneuron plasticity and strengthen the idea that neuropeptide signalling plays crucial roles in maintaining neural circuit stability. Funded by the magnificents @ERC_Research and @RosetreesT

1/10 Our latest research, led by @MartijnSelten, identifies a mechanism through which Parvalbumin (PV) interneurons regulate their activity in the #cortex. This is the story @Nature nature.com/articles/s4158… 🧵⬇︎ @dev_neuro @MRC_CNDD @KingsIoPPN @ERC_Research @RosetreesT

We are recruiting! We're looking for a dynamic, experienced Research Strategy Manager to join us. More details and application link: kcl.ac.uk/jobs/113925-re…

Only 1 week left to apply for a faculty position at the fantastic @WolfsonSPaRC Are you doing phenomenal research into spinal cord & brain repair, chronic pain or sensory systems? Do you want to join a vibrant, collegiate Centre in the heart of London? If so, then please apply!

Dev Neuro Academy: Pathways to Discovery – a new short film by Asma Bashir – showcases the ethos, experiences, and impact of this flagship widening participation initiative at the Centre for Developmental Neurobiology. Watch here: youtu.be/FIt0n2eOFWk?si…

Join us today at 1pm for our internal seminar series!

Check out the @LeverhulmeTrust feature on the exciting research by @L_andreae and Karen Page, recipients of their Research Project Grant.🔬 Read more about their innovative work here: media.leverhulme.ac.uk/feature/andera…

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