Don Ingber

I wanted to share something I have been thinking about over the last week. I asked Gemini to craft an autobiographical essay describing its development to the point where it develops consciousness. Here is what it wrote: bit.ly/4jjeY1k

Immune tissue can shapeshift and fight intruders. How does it do this? We show that stimulated B cell aggregates behave like multicellular liquid droplets whose physical state can be programmed by cytokines. youtu.be/QAk2ayoVF0M Pre-print: biorxiv.org/content/10.110…

Tune in to @60Minutes this Sunday from 7PM-8PM to learn more about how funding cuts and freezes are jeopardizing our research into potentially life-saving advances in medicine and how these actions could dismantle America’s lead in scientific innovation. paramountpressexpress.com/cbs-news-and-s…

Our work on the progression of Barrett’s esophagus into adenocarcinoma was published in Developmental Cell. Our findings suggest the need for treatment paradigms that go beyond targeting cancerous cells to incorporate stromal reprogramming. bit.ly/41djerh

So excited to see this paper on the stromal changes driving Barrett’s Esophagus progression to Cancer. A Herculean effort effort integrating scRNASeq/CODEX/ECM proteomics. Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics... sciencedirect.com/science/articl…

New paper out, amazing team @wyssinstitute - @DonIngber @mmsperry @anishvasan and many others nature.com/articles/s4385… "AI-enabled drug prediction and gene network analysis reveal therapeutic use of vorinostat for Rett Syndrome in preclinical models"

15% of the drugs in the US’s development pipeline were made by companies headquartered in MA, which wouldn't be possible w/o government investments. Funding cuts leave this ecosystem at risk. Learn more in @BostonGlobe. bostonglobe.com/2025/06/08/opi…

Is animal testing becoming obsolete? Not yet, but on yesterday’s episode of @OnPointRadio, I spoke with @MeghnaWBUR about it's used in drug development and how Organ Chips, organoids, and AI, might be used to enhance, and one day replace, these methods. wbur.org/onpoint/2025/0…

The Trump administration has launched a Blitzkrieg on science and academic freedom. As researchers, we must use our voices to advocate for science to protect patients, the economy, and truth itself. Read more in my op-ed in @TheScientistLLC. the-scientist.com/from-the-front…

I’m so excited to announce the publication of this important paper in @BioMedCentral showing the value of Organ Chips for personalized medicine and clinical care in esophageal adenocarcinoma. …nslational-medicine.biomedcentral.com/articles/10.11…

Whether it’s due to concerns for animal welfare or a desire for more successful clinical trials, more people are recognizing the importance of finding more accurate alternatives to animal models, like Organ Chips. Read more from @business. bloom.bg/43AXZ32

Boston’s high concentration of top universities, world-class hospitals, and venture capital firms makes it a perfect ecosystem for biotech innovation, but it's also left us vulnerable to the impact of political decisions. Read more from @TheEconomist. economist.com/united-states/…

I spoke with Roland Pease on the @BBC's Science in Action about the timeline for scientific innovation, the valuable partnership between the U.S. Federal Government & universities, & the economic, intellectual, & medical impacts of recent funding freezes. bbc.in/3GKetyc

Why should you care if scientific funding shrinks & academic institutions are under attack? University research drives innovation, job creation, & economic growth. Cuts threaten America's technological & economic leadership. Read more and share: bizjournals.com/boston/news/20…

When @ailsachang from @NPR interviewed me, she asked how I felt receiving the stop work orders. I was surprised and incredibly frustrated, but I remain proud to be a Harvard faculty member because we must speak truth to power. Listen here: npr.org/2025/04/17/nx-…

The @NIH is adopting an initiative to expand human-based models like Organ Chips. This tech, commercialized by @emulateinc, enables faster, better, & cheaper drug development. We'll see more successful clinical trials & better treatments. nih.gov/news-events/ne…

For anyone who cares about their neighbors & the health of their loved ones, let's fight again for freedom. Now, it's not about taxation without representation; it's about science funding cessation without justification. If this resonates, please share. wyss.harvard.edu/news/common-se…

When women spend 25% more time in poor health than men, the news that the government is slashing funding to the pivotal Women's Health Initiative highlights the importance of supporting & talking about women's health. Read more from @statnews: bit.ly/448WOtF

Last week, at least one scientific journal received a letter from a top U.S. attorney asking it to respond to alleged bias. Now, NEJM has received a similar inquiry as… trib.al/qY1xjjf

"This cautionary tale tells us much about how political interference and battles over ideology can stifle scientific advances, which are essential to improve the care of our patients." @DonIngber medpagetoday.com/opinion/second… @medpagetoday @wyssinstitute #MedTwitter #Harvard