Irene Talon

Registration to the EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies April 2-–4, 2025 is open. Great speakers, nice venue and numerous speakers will be selected from submitted abstracts. meetings.embo.org/event/25-liver…

Merry Christmas and Happy new year from the Vallier Lab. After 2 years of installation, we are now up and running. Looking forward to an exciting year 2025 full of publications, grants, fun and happiness.

Super happy/proud/honored to have been awarded an ERC advanced grant: Fun-Chol for Function of Cholangiocytes in chronic liver diseases. Very grateful for the ERC to support once again the research of @VallierLab team. bihealth.org/en/notices/dev…

Just to flag our recent review in Curr Opin Genet Dev: Exploiting the plasticity of cholangiocytes to repair the biliary tree! An overview on cholangiocytes plasticity in disease and in regeneration. doi.org/10.1016/j.gde.…

@crypt_tales Congrats Michi!!!🎉🎉❤️

🥳I am beyond to finally share the story of my PhD out now: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer nature.com/articles/s4138… Lets have a little look what we found: 🧵1/11

Our new work is out today! Long time in the oven, this has been a really fun and informative collaboration led by Dhanur Iyer in my lab and @HK_Heidar from @NRivron lab. We show that human embryonic cells have an inherent potential to regulate their developmental timing.

Check out the new episode from @stemcellpodcast 🔬 Ludovic always brings us inspiration and motivation! So happy to be part of the @VallierLab 🍄

Social Hour at the MPIMG organised by VallierBros Studios! @VallierLab @MPI_MolGen Let’s Hollywood!!!!

@bart_theeuwes Congrats Bart!! I am very happy to see this out, looks beautiful!

I’m really excited to share our research, which exploits an ESC model, chimeric embryo experiments and single-cell multiomics to uncover a role for TF Eomes in regulating extra-embryonic Mesoderm (ExEM) patterning at the onset of mouse gastrulation. 🧵👇 biorxiv.org/content/early/…

@rafaelgalupa @cecalev @FRM_officiel @laliguecancer Very nice review! Congrats Daniela et al.,! 🎉

Don't miss Daniela Cecalev @cecalev's review on "Compensation of gene dosage on the mammalian X" together with Beatriz Viçoso and myself, for a comprehensive look into X upregulation and inactivation! ⬆️⬇️ journals.biologists.com/dev/article/15… With support from @FRM_officiel and @laliguecancer

A nice video from Fabian Bachinger @VallierLab describing his research on large scale production of hepatocytes for cell based therapy. Thank you @wellcome_leap for supporting us the past 3 years #WellcomeLeap wellcomeleap.org/stories

The @VallierLab take #ISSCR2024! @ISSCR @iona_gthelwall @Frau_Carla @cagna_marta

@VallierLab will be in force at the @ISSCR annual meeting with 11 posters and 1 presentation. Please come to see us and to discuss our science.

Join us at #ISSCR2024! Attend Ludovic Vallier talk on Thursay and meet the entire/full amazing ⁦@VallierLab⁩! We will be all there for lot of science, lot of fun! ⁦@ISSCR⁩

Human TFs face a molecular trade-off between activity and specificity encoded as submaximal dispersion of aromatic residues in their disordered regions. A collaborative effort of @dhnisz, @VingronLab and Graf Lab published today in @NatureCellBio nature.com/articles/s4155…

Today at the Summer Liver Academy Meeting (SLAM) @Frau_Carla @VallierLab will present a talk on "Molecular mechanisms of human ductular reaction during progression of chronic liver disease and liver cancer" and will receive the Trainee Scholar Award on Thursday!

1/2 The presence of extraembryonic cells in the developing gut has long puzzled scientists. @BatkiJulia (l) and @hetzel_s (r) (#Meissner lab) now gained new insight into the fate and molecular characteristics of these cells. @NatureCellBio Read more: molgen.mpg.de/4717564/

Humbled & excited that our paper on molecular recording of cellular decision in Trunk-Like Structures (TLS) got featured on the cover of @Dev_Cell! w/ B. Law, M. Chan @Princeton, Z. Smith @Yale, A. Meissner @MPI_MolGen & @jvveenvliet! Link to the paper: cell.com/developmental-…

@VallierLab will be at EASL meeting @EASLnews: Wed. 6 pm L.Vallier and @IreneTalon Basic Science: Modelling of human liver-Modelling response to liver injury /Space 1+2 Frid. 3pm Carmen Costela Future of Hepatology: Translation of liver cell therapies into the clinic/Amber 3+4

@MariaOuzounova @VallierLab @Frau_Carla @MPI_MolGen @BIHregeneration Thank you Maria! it was cool to meet you and discuss :)

Thank you @VallierLab @IreneTalon and @Frau_Carla! It was wonderful to talk about cellular plasticity at @MPI_MolGen and @BIHregeneration and hear about the great science in your lab!