John F. Cryan

I’m no longer active here. This account remains as an archive of conversations, ideas, and people I valued for many years. Wishing you well elsewhere. I can be found over on Bluesky bsky.app/profile/jfcrya… and Linkedin linkedin.com/in/johnfcryan/

Can the adult hippocampal plasticity withstand a gut microbiome insult? @jfcryan et al. found that hippocampal long-term potentiation, short-term plasticity, or basal synaptic efficacy are resilient to microbiome depletion in adulthood @EJNeuroscience  onlinelibrary.wiley.com/doi/10.1111/ej…

UCC: 180 years fuelling research & innovation. UCC Futures continues to empower thinkers, makers, and leaders to shape tomorrow. @UCC, the future isn’t just imagined, it’s created. @jfcryan | @uccinnovation | @Pharmabiotic | @TyndallInstitut | youtu.be/W_IwYJYHqcI

Our fermented food intake questionnaire (FFIQ) is finally published! Thanks to the amazing team and my supervisors who made this happen @E_MSchneider, @AliceLucey2, @hennessy_aine, @pauldcotter, @Ramya_Balasub, @UCCpsychiatry and @jfcryan doi.org/10.1111/jhn.70…

Birth by Cesarean Section Remodels Neonatal Brain Barriers and Associated Immune and Metabolic Pathways in Mice biorxiv.org/content/10.648… #biorxiv_neursci

The gut microbiome maze Still much work to be done to get over many hurdles before this body of work can lead to changing the practice of medicine (beyond very narrow CDI indication of today) cell.com/cell-metabolis…

The gut<->brain axis impact on health and disease is far more important than anticipated, as reflected by GLP-1 effects, modulating the immune system, direct neural circuits, the microbiome, and more. A stellar new, open-access review @jclinicalinvest @ZachLorschMDPhD jci.org/articles/view/…

APC is recruiting a Post-Doctoral Researcher to work with @harschellekens at @UCC on a project focusing on a novel probiotic approach to target weight gain in patients taking antipsychotic medications. #jobfairy @jfcryan @UCCpsychiatry Details: bit.ly/4rGjdYE

Today @Gut_BMJ publishes my review titled ➡️My first 1000 manuscript rejections. I often meet young researchers who are devastated by a manuscript rejection, but rejections are part of life. Here are some of my most memorable ones 😃: gut.bmj.com/content/early/… @karolinskainst

#throwback REVIEW | @E_MSchneider, @jfcryan Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis nature.com/articles/s4225…

Do you have exciting research looking at interactions between xenobiotics and the gut microbiome? This special issue of Gut Microbes Reports edited by Niall Hyland and I might be the perfect venue! #drugs #bugs think.taylorandfrancis.com/special_issues…

JUST RELEASED in @EJNeuroscience Robust Hippocampal Synaptic Plasticity Despite Gut Microbiota Depletion in Adult Mice - Michael Collins & John Cryan @jfcryan @ucc @UCCResearch @UCCInnovation @pharmabiotic @AnatNeuroUCC @FENSorg @WileyBrainPsych onlinelibrary.wiley.com/doi/10.1111/ej…

JUST RELEASED Robust Hippocampal Synaptic Plasticity Despite Gut Microbiota Depletion in Adult Mice - Michael Collins & John Cryan @jfcryan @ucc @UCCResearch @UCCInnovation @pharmabiotic @AnatNeuroUCC @FENSorg @WileyBrainPsych onlinelibrary.wiley.com/doi/10.1111/ej…

Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine @gianluca1aniro & colleagues update the knowns and unknowns: loom.ly/rTGQfdY

Many research careers start with a PhD. Our new award will support healthcare professionals to take that step. We’re funding a new round of doctoral programmes to train the next generation of clinically-active research leaders. Applications are open now. Find out more ⤵️ wellcome.org/research-fundi…

Unravelling the role of the microbiome in Parkinson's disease thelancet.com/journals/laneu…

Impact is at the heart of what we do at UCC Innovation. Prof @somahony1, Co-founder of FemmeBiome discusses the motivation behind the company & supports provided on their journey to commercialisation. Find out more about FemmeBiome: femmebiome.com #EUinmyregion 🇮🇪🇪🇺

UCC researcher @Booleying is one of six Irish researchers amongst the winners of €728m ERC Consolidator awards. siliconrepublic.com/innovation/six… via @siliconrepublic

Congratulations to @UCC researcher Dr Eugene Costello, awarded a €2m European Research Council (ERC) Consolidator Grant to explore commercial cattle farming. Read More 👇 ucc.ie/en/news/2025/m… @Booleying | @ERC_Research | @jfcryan

Discovery of a gut microbiome metabolite that blocks inflammation and resistance to insulin. Its mechanism and role in improving blood sugar control may prove important treating for metabolic syndrome and Type 2 diabetes @NatMetabolism nature.com/articles/s4225…