Journal of Physiology

In this recent study, Alyssa M Lyon (@FralinBiomed) and colleagues found that steady-state #Purkinje cell activity has limited predictive power for #cerebellar output in disease 🧠 🔎 Read the research 👇️ buff.ly/Zl1hjqu

'The lactate (pa)redox of memory' Anja G. Teschemacher (@BristolUni) offers this #Perspective on the recent work of Fiumelli et al. ✍️ Read it here 👇️ buff.ly/KWZd63i

Xiang-Qun Hu (@LLUMedSchool) et al. found that #microRNA-210-mediated mitochondrial reactive oxygen species contribute to CaV1.2 channel #hyperactivity in uterine arteries of pregnant sheep acclimatized to high-altitude hypoxia 🔬 🔎 📜 buff.ly/rL0qZxZ

Nikki L. Jernigan (@UNMHSC) responds to the Letter to the Editor from Yanyu Zhang: ‘Considering a renal origin of endocrine hypertension in ASIC1a-deficient mice’ ✍️ ✉️ Read it here: buff.ly/yN6kOWF

A high-fat, high-sugar diet impairs maternal #metabolism throughout #pregnancy and lactation in mice 🍽️ 🔎 📜 Read the latest findings from Stephanie E. O'Hara (@ACEpigenetics) and colleagues 👇️ buff.ly/M6e0QRm

Recent #research by @clemlanf and colleagues observed that oleuropein-based olive leaf extract enhances #muscle mitochondrial #bioenergetics response to moderate – but not maximal – intensity #exercise in humans 💊 🚴 Read the study here👇️ 🔗 buff.ly/zTvLCQ9

In this Letter to the Editor, Philémon Marcel-Millet (@santearmees) and colleagues respond to the opinion paper by Bouchama (2025) entitled ‘Redefining human heat limits: integrating molecular and evolutionary physiology’ ✉️ ✍️ 🔗 buff.ly/9iCQmfT

📣 Call for Papers 📣 Focusing on the translation of #cellular findings into #precisionmedicine approaches 🔬 For topics and how to submit👇️ sciencedirect.com/special-issue/… 📨 Submission enquiries to jpm@physoc.org

We love our editorial board fellows @JPhysiol. Thanks, Joe, for your thoughtful blog. physoc.org/blog/dr-joe-we…

'Redox balance and metabolic flexibility in fast-twitch oxidative–glycolytic muscle fibres: rethinking aerobic lactate production' McKinley A. Kennedy (@MoveUofT) and co-authors discuss the work of Disch et al. (2026) in this recent #JournalClub ✍️ 🔗 buff.ly/q0peZzJ

'Seeing is believing: metabolic sensors illuminate cell‑specific metabolic requirements' Nuno Valente-Leal and Zita Carvalho-Santos (@GIMM_Institute) offer this #Perspective on the recent work of Müller et al. ✍️ 💭 🔗 buff.ly/VAeVRrZ

In this review, Mohammad-Reza Ghovanloo & Stephen G. Waxman (@NeurologyYale) provide a framework for understanding the nuanced role of #Nav channels in health and disease ✍️ 🔬 Read it here 👇️ 🔗 buff.ly/QC4xKmO

Hubert Fiumelli (@KAUST_News) et al. reveal a #molecular pathway by which #lactate, produced by astrocytes, can significantly influence neuronal activity and synaptic function, linking brain metabolism with learning and memory processes 🧠 Read it here: buff.ly/TSSoaJr

New research from Stephan Müller and colleagues (@tudresden_de) observed that #neuronal loss of the pentose phosphate pathway in the living nervous system is causally linked to #NADPH reduction and elevated oxidative stress 🔬 🧠 Read the study👇️ buff.ly/hX6BENr

'Light-based pain killer: Transcranial photobiomodulation for pain suppression' Suyash Mehta and Cushla McGoverin (@UoA_Physics @DoddWalls) examine the work of Wang et al. (2026) in this recent #JournalClub article ✍️ 🔗 👇️ buff.ly/qKPUEMy

Thomas H. Topham (@UniCanberra) and colleagues investigated the influence of age and biological sex on #sweating in children exercising in warm and hot environments with comparison to adults 🌡️ 🏃‍➡️ Read the study👇️ buff.ly/skd64HV

'Melanocortin 4 receptor signalling in sleep-disordered breathing' Md Tarikul Islam and colleagues (@GW_Anesthesia) review the MC4R pathway in respiratory control🛌 🧠 Read it here 👇️ buff.ly/s4wlcP5

Submit to the Special Issue **Preterm Birth: Physiology, Pathophysiology and Metabolic Diseases** @JPhysiol Clinical, translational, and basic science perspectives No publication fees Information: lsobrevia@uc.cl, sobrevia@me.com, ra2menon@UTMB.EDU

'What homeostasis leaves out: Kinorhesis, a physiological principle of transformation' 💭 ✍️ Read this recent #Opinion article from Nelson D. Horseman (@UCPPNDept) 👇️ buff.ly/wvS68I3

Takuya Kurazumi (@UTSWNeurology) and colleagues present a cascade model of dynamic cerebral #autoregulation in this recent study 🫀 ➡️ Read the #research: 📜 buff.ly/M83QQQy