Howitt Lab

Not the first and likely not the last review on tuft cells. But for sure the most recent one, published in @NatRevGastroHep: Kalle and @XiaogangFeng did a great job summarizing recent findings related to tuft cells nature.com/articles/s4157… full-text access: rdcu.be/dVaOi

Congrats Miles on a great talk at FASEB Gastrointestinal Tract XXI. It was our labs first time at this meeting and sure we will be back. #GTSRC24

Online now: Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation dlvr.it/T9wX6X

@UChicago_Micro @GerrickElias Congratulations Eli! Everyone in the Howitt lab is so excited for you. U Chicago is getting an amazing scientist and colleague.

Please join us in welcoming our newest faculty member to the University of Chicago Department of Microbiology, Dr. Elias Roth Gerrick @GerrickElias, who will join as Assistant Professor effective September 1, 2024. (1/3)

Online now: Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity dlvr.it/T6qpgG

We're looking for a Research Associate/Technician to join our lab studying microbiome-immune interactions in the gut. We are open to recent college graduates and/or applicants expecting to graduate soon. Previous research experience is helpful, but not required.

@schumacherama @Mucus_Man Beautiful image. I would suspect they're "intermediate cells". We saw them with commensal protist colonization and others have seen with helminth infection. It would be cool to figure out what they do or if they can transition into more canonical Paneth or goblet cells

@Mucus_Man This is a mutant mouse but I think there’s a microbiota component. Let me know if you ever want to figure them out

Lysozyme+ cells out of place Released from the intestinal crypt base #immunofluorescence #microscopy

Very excited to share our paper led by @madisonstrine Intestinal tuft cell immune privilege enables norovirus persistence | Science Immunology science.org/doi/10.1126/sc… 1/n

New preprint from the Bhatt lab! Congratulations @DanicaSchmidtk1 and Angela Hickey!!! 🎊

If you’re interested in host-microbiota interactions but like your microbes with membrane bound organelles then our paper on symbiotic protists is for you @CellCellPress . Congrats @GerrickElias and a huge thank you to all our collaborators! cell.com/cell/fulltext/…

💥Tenure-Track Faculty Job Alert!💥 Monell has an OPEN SEARCH for MULTIPLE positions (all levels) If you study feeding behavior, metabolism, nutrition, olfaction, taste, chemesthesis, stem cells, or other topic in chemosensory biology, apply! 1/ apply.interfolio.com/79129

I hadn't thought much about the reptile microbiome before but @GerrickElias curiosity and pet tortoise inspired this story on intestinal protists in wild and domestic reptiles. Big thanks to our collaborators Tim @maddreptiles and Freeland @calacademy journals.asm.org/doi/10.1128/mb…

Announcing the 2023 Stanford Immunology Preview event! If you’re interested in applying to our PhD program, you’re invited to this virtual event. You’ll hear from our amazing faculty and students about what makes our scientific community so vibrant. bit.ly/stanfordimmpre…

Why do intestinal tuft cells sense succinate when it doesn’t appear to help them clear parasites? Our collab with the Salzman lab at MCW sheds some light on this question. Congrats Connie, Lisa, and Gabe @gabebarron for all your great work! @PNASNews pnas.org/doi/10.1073/pn…

Check out this really cool story from the Moltke Lab @jakob_moltke @TBillipp showing how acetylcholine from tuft cells can regulate epithelial fluid secretion and help clear worm infections from the gut! Excited to have been involved in this incredible work.