Insco Lab

🎉 Huge congratulations to Kaiwen for receiving a National Cancer Center Postdoctoral Award! 🏆Your hard work and dedication are truly inspiring. Excited to see all the amazing research ahead! 👏 #ScienceExcellence #CancerResearch #Postdoc

Thanks to all for making this possible! @Swathy_BNK #JChen #CBaron #KSun @EmRobitschek #AMcConnell @wustance @dedeilia @sadefeld @RodsyM97 #MManos #KYChen #AMCox @calvin__ludwig @manoliskellis @bbuchbinderMD #NHacohen @yangjiekun @gmboland @TheAbraLab @dliu_ccb @leonard_zon

Motivated by caring for patients with mucosal melanoma (MM), we built the first animal model of this lethal disease and revealed that the cell of origin explains MM’s metastatic and immune-evasive nature.

Thrilled to share the first publication from @InscoLab in @NatureComms! nature.com/articles/s4146…

@yangjiekun @gmboland @TheAbraLab @dliu_ccb @leonard_zon

Thrilled to share our first independent manuscript! We reveal that recurrent mutations in ZC3H18 stabilize endogenous retroviral RNA, which contributes directly to oncogenesis. Thanks to @BoutzLab, @burns_lab, @NCIChanock, @kbrowngenetics and the rest of our co-authors!

Welcome to Allison Williams!! Allison is a new post doc in the lab who LOVES all things RNA (especially structure), so we greeted her with a zebrafish comprised of RNA structures😁

The 2024 Insco Lab Retreat was super fun and scientifically illuminating!

Congratulations to @danafarber researchers Erin Parry, MD, PhD (@ErinMParry), Lachelle Weeks, MD, PhD (@Lachelle_Dawn), and Megan Insco, MD, PhD, who were awarded the Damon Runyon Clinical Investigator Award. Read more ms.spr.ly/6013ll1QP

Ice cream outing to celebrate Scout's first and Anna's last week😀

Hobby/craft party to celebrate Anna's success with her PhD applications!

So excited to welcome Kaiwen Sun as a postdoc in the Insco Lab!

2nd Annual Insco Lab Retreat in NH!

Insco Lab summer picnic!

I am running the B.A.A. Half Marathon this year as part of Team @DanaFarber! My goal is to raise $500-$1000 for the Jimmy Fund, a charity that provides funds towards cancer patient care and research. Please donate if able, or share the link, thank you! danafarber.jimmyfund.org/site/TR?px=250…

A huge welcome to our new Insco Lab members! Christina helping in the fish room, Gautier here for the summer, and Priyanka a new computational post doc!

Congratulations to Tanzina for receiving a NCC 2023 fellowship!

A new cancer mechanism — inability to degrade defective RNAs — appears to cut across many different malignancies and could present a whole new set of cancer targets. Kudos @InscoLab & @leonard_zon. Learn more 👇 #CDK13 #ZC3H14 ms.spr.ly/6011gpiWH

Read this week's #ResearchWatch: Mutant CDK13 Triggers Oncogenic RNA Processing Defects in #Melanoma, a summary of the paper by @InscoLab, @leonard_zon et al. bit.ly/42tlitv @BostonChildrens @DanaFarber