OpenEye, Cadence Molecular Sciences

Want to learn how to increase throughput up to 5-10X higher and cuts costs by 50-80% over traditional equilibrium methods such as free energy perturbation (FEP) or thermodynamic integration (TI)? Ask us how! hubs.ly/Q03SPqvG0

A huge thank you to everyone who joined us at miniCUP Osaka. Your energy and engagement made the event a massive success!

We had another great science meeting at miniCUP Tokyo - thank you to everyone who attended and contributed to the discussion!

There is still time to register for our miniCUP events in Tokyo and Osaka. Register here: hubs.ly/Q03M9cn90 #CompChem #ComputationalChemistry #DrugDiscovery #DrugDesign #MedChem #MolecularModeling #MolecularDynamics #創薬 #計算化学 #AI創薬 #メドケム #分子モデリング

Our European team is excited to attend the #FestivalofBiologics on Sep 30-Oct 2 2025 in Basel. Stop by booth 273 to discuss how our work in AI and physics-based design for biologics can be applied to help solve some of your biggest development challenges!

We are heading to Discovery On Target in Boston, Sept 22–25! Let’s talk molecular modeling, drug discovery, and innovation in pharma R&D. #BostonDOT #drugdiscovery

What is next in drug discovery? Watch Geoff Skillman and Jeff Blaney of @genetech discuss that now! hubs.ly/Q03GSRZf0

Why are problem solving courses so important for new scientists? Watch David LeBard and Ken Dill of @stonybrooku discuss that and the next era of drug discovery now! eyesopen.com/news/conversat…

Affinity prediction, upgraded. Our 3D-QSAR model uses machine learning with shape + electrostatics to predict binding affinity with high accuracy—and includes error estimates to guide smarter decisions. Better predictions. Better prioritization. hubs.ly/Q03Br5cB0

KRAS was “undruggable” for 30+ years. Learn how OpenEye's Cryptic Pocket Detection workflow found a novel pocket. 📣 Webinar: Drugging the undruggable: A highly accurate method for detecting and ranking cryptic pockets 📆 Aug 14 | ⏰ 11–11:30 AM EDT hubs.ly/Q03Br5fj0

Join Us & @EnamineLtd for an exclusive webinar to explore 3D molecular search + chemical space tools that speed up drug discovery. 📅 Register now: us06web.zoom.us/webinar/regist… #DrugDiscovery #MedChem

Our team will be presenting at ACS Fall 2025. Don't miss these exciting talks!

OpenEye’s Non-Equilibrium Switching (NES) on the Orion® platform delivers fast, cost-effective binding free energy estimates—ideal for iterative lead optimization. Read the science brief to learn more! hubs.ly/Q03zLw9_0

OpenEye, Cadence Molecular Sciences recycled 1000lbs of e-waste. Read the story now! hubs.ly/Q03yJX3Q0

Ever stop to smell the flowers? Check out the wildflowers currently growing all over our Bis-BEE office location. See the pictures now! hubs.ly/Q03xx_b80

Recently, OpenEye, Cadence Molecular Sciences welcomed retired scientists and engineers for a tour at our Santa Fe office. Afterward, they participated in a scientific discussion with our team and offered wisdom from their careers.

Register now for OpenEye's fall 2025 miniCUP events! Agenda: • Trillion-scale 3D virtual screening • CryoEM map fitting with weighted ensemble MD • 3D ML-driven lead optimization • Revealing cryptic pockets for new drug targets ... and much more! hubs.ly/Q03wcZQy0

Preparing chemical databases for 2D and 3D search is laborious and costly - let us do the heavy lifting for you. Prepared vendor databases available for search on Orion and Orion Molecule Search, where we provide near-instant similarity search results. hubs.ly/Q03vtF080

We are excited for #RICT2025! Visit booth # 10 to learn how scientists are using our cryptic pocket detection on Orion to find previously hidden binding sites in proteins like KRAS. #DrugDiscovery

There is still time to register for our webinar tomorrow: "Bayesian sampling in OMEGA for small molecule conformer generation" 🗓️ June 26 | 11–11:30 AM EDT hubs.ly/Q03tpw8X0