Sebastian Scheer

@Dr_HeFeng @LIH_Luxembourg @FnrLux @lcsb_uni_lu Congrats! Well done!

Wanna know within first hours of treatment whether allergen-specific immunotherapy will work? Via systems immunology analysis in ~200 patient samples, we identify a uniform molecular pulse in those with the highest cure @LIH_Luxembourg @FnrLux @lcsb_uni_lu nature.com/articles/s4146…

@HSudholz @Dr_Nick_Bikes What a pleasure it was! Congrats and well done!

Phd thesis submitted, what a journey. Thanks to @Dr_Nick_Bikes and @SebScheer for their supervision over the past few years. Hawthorn will be back next year.

NK cells are an important anti-cancer defense, but what happens if they turn into a different cell type? A new study from @SebScheer @Dr_Nick_Bikes identified a gene without which NK cells turn into a weaker cell type, making them worse at fighting cancer. bit.ly/3SKxSCl

Happy to share our new NK cell resource in @NatImmunol: "Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping." nature.com/articles/s4159…. @herknet, @AlinePfefferle, @AmirHorowitz @humancellatlas, @CoE_PRIMA, @UniOslo_MED

Thrilled to announce the publication of our latest research in Nature Immunology. Joining forces with 20 laboratories in Europe and USA, we identified the three prominent NK cell subsets in human: NK1, NK2, and NK3: rdcu.be/dMuAs

Junior Research Group Leader position: Join the Würzburg Infection and Immunology community! nature.com/naturecareers/…

In our review article, we now assess the current literature and highlight challenges and possibilities around the "conductor" DOT1L and its immunomodulatory functions, that may pave the way for innovative therapeutic approaches. bit.ly/3z9jYmg

...followed by @liamkealy and @KimLJacobson discovery of DOT1L's importance in B cells. bit.ly/3xrMrDl

After our discovery of DOT1L's role in NK cells bit.ly/3XsfSQc @CellReports, we now published the cherry on top of 7 years of research on DOT1L in the immune system @MonashBDI and @LIH_Luxembourg! @JessicaRunting @DrDThiele @liamckealy bit.ly/3z9jYmg @FnrLux

New publication from our lab 📣 cell.com/cell-reports/f… We demonstrate that Histone methyltransferase, DOT1L, limits NK cell conversion to ILC1s, a subset that can be observed in tumors in response to TGF-β and is correlated with poor tumor control @HSudholz @SebScheer

🖐A new #job opening for a 2-y position as a postdoc in my team! 🔺I'm considering only applications which include responses to the 3 questions I asked in the ad ;) So, read it before applying. 🙏 Help me circulate that job offer :) lih.lu/fr/job-fr/?val… @LIH_Luxembourg

Back home after a wonderful meeting of Functional Epigenomics in Saarbrücken. Going back to @LIH_Luxembourg with many new inspirations and the excitement that understanding and exploiting epigenetic mechanisms in immune cells will be key to solve many problems in the clinic.

@colbyzaph Big congrats to these exceptional students! However, also a big „well done“ to the PhD „dad“.

Three students at one graduation! So proud of them all.

Huntington and colleagues describe the functions of Ikaros and Aiolos in NK cell development. Read it here: rdcu.be/dvLeC #Abs1" target="_blank" rel="nofollow noopener">nature.com/articles/s4159…

What Harry says. Well done, team!

I am hiring, please RT🙏🙏 POSTDOC: a molecular biologist to study the mechanism of chromatin modifiers in gene repression. careers.adelaide.edu.au/cw/en/job/5127… RA & LAB MANAGER: a protein biochemist & to lead the laboratory operations within a brand-new lab. careers.adelaide.edu.au/cw/en/job/5128…

En route to #nk2023!

Welcome to the @IEE_Research_Gp team, May Wantz! May will work on the epigenetic regulation of NK cell function as part of our @FnrLux and @FondationCancer funded EPICON project @LIH_Luxembourg. May you do well! 😉

A @MonashBDI study has found that a protective immune feature may be lacking in people with chronic infections caused by parasitic worms, which can help lead to improved #treatments and human vaccines. @MonashCCS #globalhealth Read it on @MucosalImmunol: #full-view-affiliation-1" target="_blank" rel="nofollow noopener">pubmed.ncbi.nlm.nih.gov/37392971/#full…