TrustPointe Analytics 🥼

ChatGPT said I should start using “pharmaceutical-grade methods” because nobody knows what USP <1225> validated methods means. What do you think?

So interesting to watch the space step out into the open 18 months ago, consumers would have blacklisted your lab for talking to the media theguardian.com/science/2026/a…

Day 3 of waiting for another lab to post their tirz method validation results

@Alexfreiberger We are an Agilent house, so we are using Agilent stacks and Openlab CDS. We have an Agilent Crosslab contract for maintenance, and we qualify our systems (wavelength accuracy, flow rate accuracy/precision, gradient, injection, etc) annually or when there is a significant repair

@TrustPointe What instrumentation and software are you utilizing? Are they qualified systems?

We now have validated HPLC methods for GHK-CU, GLOW, KPV, and KLOW 👍🏻🥼👩🏼‍🔬

I think I’ve caused enough damage on X for today!

@fsasjohn @PeptidePartners @ZakDavid I feel like Ashlee feels this way every time I tell her what I posted here 😬

@PeptidePartners @ZakDavid right now 🤭

boss man gave me full control of this account finally, youve been warned.

@rorynotsorry 💯 We started TrustPointe because we saw what was available, and with our background in pharma QC knew we could improve transparency and harm reduction in the space Keep doing what you’re doing; you’re a catalyst for change!

I know I’m on the right side of Peptide Twitter, when I have analytical laboratories and other organizations debating detailed aspects of testing in my comments and feed. There is this assumption that everyone in the Gray world is dodgy or out to make a dollar. There is a surprising subset of people that actually deeply care about quality.

@PeptidePartners Welcome to the Thunderdome!

@TrustPointe We have SOPs in place. Every step is documented from the time it's ordered to the time it's put in stock. We keep this documented so if there's issues between our manufacturer to our own internal team we know where to find an issue.

I also think that businesses that make having a quality system part of their strategic roadmap moves them closer than their competitors to stepping out of the grey and into the regulated market

As the low control market becomes more “commoditized” and prices race to the bottom, one way business have an opportunity to differentiate themselves is by advancing their critical quality processes: Formulation Studies (AET, etc) Stability Studies & Expiration Dating Supplier Controls Change Control Document Control Identification and Traceability (real traceable lot numbers Process Validation Etc etc

Don’t get me wrong: every improvement is a step in the right direction. And accessibility may trump quality concerns. But there is a long, long, … long road ahead for this space to mature to the same quality level as a bottle of ibuprofen you buy off the shelf at Walmart

Smart

It will. There’s a constant pipeline of new consumer injectables from drug companies, research papers, and even drug candidates that didn’t complete clinical trials endpoints but still demonstrate efficacy for some people. For the first time, people are empowered to make their own health decisions, and the market moves faster than gov ever can or will.

@TrustPointe if the market survives?

I love this change by Finnrick. I actually built most of my following and social media a year ago based on calling out companies for not doing batch IDs. Hopefully this drives the overseas vendors to start doing it more.

This is cool

@rorynotsorry While dreaming for more! That’s why I love this space - so much opportunity to grow and improve as the market matures.

@TrustPointe We do the best we can

@rorynotsorry This is like Purity where I had to go around and burst everyone’s false sense of security bubble on what it actually means 🤣 (sorry, but scientific rigor and quality control is my passion)

Batch numbers are only as good as the lot identification and traceability controls behind them, and trust me, they aren’t there. In an ideal state, a single lot number would trace back to one vial batch and one mixing batch. If anything was wrong, you could recall the one lot and get all the bad product. In general (sure there are exceptions), this level of control doesn’t exist in this market, so shipments of 20mg tirz are mixed vials from multiple production lots, rendering lot numbering after meaningless. Based on the report from @QualseraMark, we have a hard enough time knowing what is in the vial (identification) 🤣