Remember to follow us from now on at @consciencemeds! See how the story continues on #OpenScience drug development there.
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ViMI
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Please follow us at @consciencemeds to keep up to date on our work and announcements!
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We are very happy to announce that we are now operating under the name Conscience (@consciencemeds) following the transformative funding from @ISED_CA & Minister @FP_Champagne to build a game-changing drug development program based on open science and AI.
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AlphaFold touted as next big thing for drug discovery — but is it? To find out “what is needed is a transparent process like CASP”. We agree, and the CACHE hit-finding benchmarking challenge is well underway. Hype meets reality!
nature.com/articles/d4158…
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I am shocked & appalled that the Canadian National Vimy Memorial, a sacred space honouring the 60,000 Canadians who gave their lives in Europe during the First World War, was vandalized.
We are working with French authorities to find the person responsible.
My statement:
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Sobering reality of fragment-based drug discovery. 23 world class scientists were given a structure with fragments bound, and challenged to use this information to predict a potent inhibitor(s) from a pool of 6B compounds. Each had 100 shots on goal. Outcome? There “may” be hits.
Matthieu Schapira@mattschap
Experimental data for CACHE#2 Round#1 are out (1957 compounds predicted by 23 participants). 46 hits from 18 groups advance to hit expansion round. The wind is coming from expected AND unexpected places. Final results for CACHE#1 are next - in December. bit.ly/47uxBcq
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All 1739 compounds shipped by Enamine in Kyiv and predicted by 25 CACHE#3 participants to bind SARS-CoV-2 NSP3 Mac1 are now received in Toronto. Screening by HTRF and DSF @thesgconline and by crystallography at UCSF's @fraser_lab about to begin! bit.ly/41HIW4X
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Despite the heat outside, we will be cooking up a storm re #OpenScience indoors at @thesgconline, talking about drug discovery through the TRIDENT preclinical platform and @VIMIOpen's drug discovery ecosystem!
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Addressing #AntimicrobialResistance is a crucial effort, because the clock is ticking. Every day that passes, the threat increases.
The world needs a comprehensive and well financed action now to prevent drug resistant disease developing & spreading.
We have no time to waste.
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#OpenScience #Partnerships aren't rivals to other innovation models; they're an additional lane on innovation highway!🚗By fostering collaboration, knowledge sharing, & unlocking new opportunities, they complement existing approaches, helping firms reach their destination faster.
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Harness magic of research & innovation with open tools, databases, and materials! 🧪✨ #OpenScience #Partnerships hold key to success, making it easier & more cost-effective to manage these vital resources. Let's embark on a journey of collaboration & discovery. 🚀🔬 #Innovation
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We face a choice: fight #GlobalHealth issues like pandemics, AMR, & more, or repeat past mistakes. Patents & knowledge hoarding won't cut it. #OpenScience partnerships are way forward. They ensure global access and speed up treatments to save lives. Let's make the right choice.
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🔬💡 Open Science Partnerships are transforming the game! By enhancing replicability of research results, we're saving billions in wasted studies. Better data quality = increased chances for commercialization and innovation. Join the revolution! #OpenScience #Innovation
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Collaboration, transparency, and accessibility pave the way for innovation to flourish. Let's embrace the power of open science to drive both scientific advancement and economic growth! #OpenScience #Innovation #Commercialization#
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#OpenScience isn't just about sharing knowledge; it's also a gateway to diverse commercialization opportunities. By embracing openness, researchers and innovators unlock multiple channels for turning their discoveries into real-world applications. 1/2
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🌐 Embracing #OpenScience #partnerships is crucial for advancing knowledge & accelerating progress! By joining forces across disciplines, institutions, & countries, we unlock true potential of collaboration, innovation, and discovery. Let's amplify our impact together. 🤝🔬
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714 chemical follow-ups of compounds of interest selected by 18 participants to CACHE #1 arrived last week from Ukraine. Experimental screening against LRRK2 to begin this week! All data expected to be released in December. Prelim. results: bit.ly/3KirdLX
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Looking for post-doc at @mcgillu for #innovation economist to work with transdisciplinary team examining open science incentives, benefits, and costs. Will have time for own projects. Working with @jackieAsullivan on TRIDENT team. Apply through: mcgill.wd3.myworkdayjobs.com/en-US/mcgill_c…
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"Unfortunately, Canada is not yet in a position of leadership in [Open Science]. The Tri-Agencies do not provide any dedicated funding competitions for OS research nor is there public facing monitoring to track our performance and benchmark for improvement."
FACETS Journal@FACETSJournal
NEW in @FACETSJournal | @dmoher and @KDCobey discuss the White House’s march towards #OpenScience, and its implications for Canada ▶ buff.ly/43rZ5gn
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