Carlos Silva Rosas

This study characterizes the risk of major congenital malformations in infants born to women using common antiseizure medication polytherapies during the first trimester. Read more: hubs.la/Q04kbPTW0

🧠 Big news for stroke care from the T-FLAVOR trial! Standard-dose tenecteplase 0.25 mg/kg beats low-dose alteplase 0.6 mg/kg—the standard of care in Japan and parts of East Asia—by achieving a nearly 3-fold higher rate of early substantial TICI reperfusion 10.3% vs 3.6% in acute ischemic stroke patients with large-vessel occlusion scheduled for mechanical thrombectomy ⚡️ Safety profiles were highly reassuring with similar rates of symptomatic ICH hemorrhage 2.8% vs 1.8% and 90-day mortality 6.5% vs 9.9% between groups 📉 This world-first head-to-head data positions tenecteplase as a highly promising thrombolytic option to streamline stroke workflows in regions currently relying on low-dose alteplase 🏥 Source: Inoue M, Hirano T, Fukuda-Doi M, et al. Standard-Dose Tenecteplase vs Low-Dose Alteplase for Acute Ischemic Stroke From Large-Vessel Occlusion: A Randomized Clinical Trial. JAMA Neurol. Published online June 1, 2026. doi:10.1001/jamaneurol.2026.1590

Patients with iatrogenic cerebral amyloid angiopathy (CAA) exhibit higher amyloid burden and a distinct biomarker profile compared with those with sporadic CAA, supporting a divergent—possibly exogenous—mechanism of amyloid propagation: hubs.la/Q04jpnCB0

Great @Radiopaedia case by Dr Paul Ryan demonstrating Biffl grades I-IV blunt cerebrovascular injuries all on a single patient! 😱 radiopaedia.org/cases/blunt-ce…

EASY ONE 🔥🔥 Elderly patient with chronic kidney disease on dialysis, presenting with confusion, tremors and choreiform movements. MRI Brain (T2/FLAIR axial). What is this classic sign? 👇 What are your differential diagnosis? #MedX

Mechanical stress from dystonia can cause arterial dissection and stroke. @Divyani_Garg reports this combination in a case with genetically proven PKAN. Chronic iron deposition may also cause vascular fragility in NBIA spectrum disorders. @neuro_ian Link: 10.4103/aian.aian_21_26

En el HBLT superamos las mil trombólisis, gracias al trabajo coordinado de nuestros equipos y lo conmemoramos en una ceremonia donde recibimos la certificación de Angels Initiative y nos acompañó el primer paciente trombolizado. Con un 94% de efectividad, seguimos salvando vidas

And we use it in CNS TB. Had quite a few favorable results. Learned it from Dr Manish Modi. And some more.. @docakx

El MOGAD es el "gran impostor" de la neuroinmunología. 🧠 Pasa años confundido con Esclerosis Múltiple, pero tratarlo como EM puede exacerbar los brotes. 🚩 Red flags: 1️⃣ Neuritis óptica bilateral/severa. 2️⃣ Respuesta dramática a corticoides. Abro hilo 🧵👇

@JordanHNewman @zach_london I agree

@zach_london Neuromuscular Examination Without Muscle Assessment: Negligent

Any doctors out there subconsciously choose their medical specialty because their last name is an acronym for it, or is it just me? Late-Onset Neuromuscular Diseases Or Neuropathy.

De @ACEVE_Chile me invitaron a dar una charla sobre “Cefalea y ACV” Un tema con muchas caras, mucha controversia, pero con buenos datos recientes que obligan q actualizarse! 🧠🥴 Inscripciones👉luma.com/2m8i63zf

Encephalopathies @drcyncity

@docakx seljalandsfoss. Diagnosis ?

FOOT DROP Fibular (peroneal) neuropathy vs L5 radiculopathy! You have a patient come in with a foot drop. There is no pain, but they have a history of low back pain. How do you differentiate between an L5 radiculopathy and fibular neuropathy in the clinic?

A young man 👨 with slowly progressing gait disorder and sleep apnea (due to recurrent tongue fall back at night) Mother died of a similar illness Mri shows this

Enjoy! iies.unam.mx/libros/Manual-…

Jake Sossamon, PGY-1 Stanford Neurology resident, has launched The History of Neurology Podcast to explore the human drama, wartime breakthroughs, and accidental discoveries that shaped our specialty. Episode 1: "The 'L' is Not Silent: The Secret History of Guillain-Barré" can be found on Spotify, Apple Podcasts, or Amazon Podcasts. podcasts.apple.com/us/podcast/his…

Ha fallecido uno de mis maestros, el Dr Jorge Tapia Illanes. Profesor Titular de @FacmedicinaUC, Discípulo de Miller Fisher, Jay Mohr, Louis Caplan y EP Richardson. Pionero de la neuropatología y neurología vascular en Chile. Maestro de la neurología chilena @sonepsyn 2018, destacado por su aporte a la especialidad como gran docente formador de decenas de generaciones de médicos y neurólogos. QEPD 🕊️, muchas gracias por todo lo que aprendí de él y a seguir el legado de enseñar neurología “stroke by stroke” 🧠

@neuropuc @FacMedicinaUC @Sonepsyn Mis condolencias, Patricio. Asimismo, para todo el departamento. El Dr. Jorge Tapia fue un gran profesor.

Doughnut sign is a well described finding in Dengue encephalitis. The prognosis of this sign is unknown and it does not correspond to the degree of thrombocytopenia. Garg et al describe a rare case of "Dual Doughnut sign" in Dengue encephalitis. Link: 10.4103/aian.aian_954_23