Daniel Corner

Top 3 free JavaScript tutorials for beginners, from a "self-taught" developer: 1. FunFunFunction functional programming in JavaScript bit.ly/1ONgo2m 2. Wes Bos JavaScript30 bit.ly/2Fsgqgc 3. Programming with Mosh JS for Beginners bit.ly/2ZEsPp1

this OpenClaw bot finds warehouse owners & books them solar deals on autopilot... here's how solar business owners can use it to close $500k+ commercial installs: - scans 1000s of warehouses via satellite imagery - scores every roof by size, sun hours & payback - pierces the LLC to find the actual human owner (not info@) - renders their building with panels on it + 25-yr savings - ships them a personalized microsite at their company name - follows up across email, sms & linkedin - books calls straight to the calendar 24/7 reply "SOLAR" + RT and i'll send you the full breakdown of how you can do it too (must be following so i can dm)

Every time you get a cancer biopsy, the lab makes a tissue slide that costs about $5. It shows the shape of your cells under a microscope, and every cancer patient already has one on file. There’s a much fancier version of that test called multiplex immunofluorescence (basically a protein-level map showing which immune cells are near your tumor and what they’re doing). It costs thousands of dollars per sample, takes specialized equipment most hospitals don’t have, and barely scales. But it’s the kind of data oncologists need to figure out whether immunotherapy will actually work for you. Right now, only about 20 to 40% of cancer patients respond to immunotherapy, and one of the biggest reasons is that doctors can’t easily tell whether a tumor is “hot” (immune cells actively fighting it) or “cold” (immune system ignoring it). Microsoft, Providence Health, and the University of Washington trained an AI to analyze the $5 slide and predict what the expensive test would show across 21 different protein markers. They called it GigaTIME, trained it on 40 million cells in which both the cheap slide and the expensive test coexisted, and then turned it loose on 14,256 real cancer patients across 51 hospitals in 7 US states. The results landed in Cell, one of the most selective journals in biology. The model generated about 300,000 virtual protein maps covering 24 cancer types and 306 subtypes. It found 1,234 real, verified connections between immune cell behavior, genetic mutations, tumor staging, and patient survival that were previously invisible at this scale. When they tested it against a completely separate database of 10,200 cancer patients, the results matched up almost perfectly (0.88 out of 1.0 agreement). Nature Methods named spatial proteomics (mapping where specific proteins sit inside your tissue) its Method of the Year in 2024, and specifically cited GigaTIME in a March 2026 update as a model that “democratizes” this kind of analysis. The full model is open-source on Hugging Face. Any cancer research lab with archived biopsy slides, and most of them have thousands, can now run virtual immune profiling without buying a single piece of new equipment.

today’s experiment: chimera. a little tool that let’s you realtime morph through a design system matrix generated by 4 reference images. this one was inspired by listening to @jameygannon talk about her process on Dive Club with @ridd_design and How I AI with @clairevo. her approach to choosing moodboards over prompts made me wonder what might be possible if we applied that same approach to generative UI. and after a few dead ends, the idea turned into chimera. the results are very generic at the moment but I might tune it up if people seem interested. the big reminder for me is how much more inspiring a tool feels when you can explore in realtime instead of waiting for results every time you make a change. lots more things to try in that direction.

Human population density around the world. 📽: Tyler Morgan-Wall

@anishmoonka Several scientists have raised concerns that the measurement method can confuse brain fats with certain plastics (like polyethylene), which might overestimate how much plastic is really there. microplasticsolution.com/post/a-spoonfu… open.spotify.com/episode/2ZwZsC…

Your brain is 0.5% plastic right now. About 7 grams, the weight of a plastic spoon, broken into billions of tiny shards just two to three times the size of a virus. A 2025 Nature Medicine study analyzed cadaver brains going back to 1997. Brain tissue from 2024 had 50% more plastic than samples from just 2016. The concentration is doubling roughly every 10 to 15 years, tracking almost perfectly with global plastic production, which went from 2 million tons in 1950 to over 460 million tons today. The dominant plastic is polyethylene, the same material in your grocery bags, food packaging, and water bottles. The brain accumulates more than any other organ because it’s the second fattiest in your body after body fat itself, and plastics are naturally attracted to fat. Your brain also receives 25 to 30% of all blood your heart pumps. Researchers found the particles hitchhike on the same fat-transport molecules your body uses to deliver dietary fats to organs. It’s a normal pathway you can’t shut down without starving the brain of energy. The health data is piling up. Dementia patients had 3 to 5 times more plastic in their brains than people without dementia. Mice exposed to microplastics in drinking water for just three weeks developed dementia-like behavior. A 2024 New England Journal of Medicine study found that patients with microplastics in their carotid artery plaque had 4.5 times the risk of heart attack, stroke, or death over 34 months. A Duke University report estimates US health costs from plastics at $410 to $930 billion per year. Crucial caveat: the dementia link is correlation, not causation. Dementia already damages the blood-brain barrier, so diseased brains may simply let more plastic in. The science is early. But plastic production is still accelerating, concentrations in our brains are still doubling every decade, and no one has identified a mechanism for the brain to clear these particles once they arrive. We’re in the 1960s-era cigarette moment for plastics: plenty of smoke, not enough long-term data, and zero signs of slowing down.

@forallcurious Several scientists have raised concerns that the measurement method can confuse brain fats with certain plastics (like polyethylene), which might overestimate how much plastic is really there. microplasticsolution.com/post/a-spoonfu… open.spotify.com/episode/2ZwZsC…

NEWS🚨: Average human brain noow contains 7grams of microplastics, 30x higher than other organs

Watching a castle emerge from noise in Minecraft is pretty damn cool 🏰

@forallcurious Zoomed in, looks like a Pollock painting

new cc0 site is live! 900+ free glbs to grab at ease ready for your @threejs experiments, game projects, etc need some polishing, but is working if you're a dev, you might wanna use the asset registry repo directly more assets soon, stay tuned opensource3dassets.com enjoy

Growing Graphs demo is finally out! 🕸️✨ 🔗 znah.net/graphs/ Videos from a few months ago finally meet a finished implementation, thanks Gemini for doing the boring parts. Inspired by Paul Cousin's Graph-Rewriting Automata: like a Game of Life, but cells can split if they want to #GenerativeArt #WASM #SwissGL

Big thanks to everybody who encouraged me on this whacky gamedev journey! Today I replaced the complex cloud system with a simple shader and tuned some of the sound effects #gamedev #indiedev #devlog

@dangreenheck It looks a lot like florasynth.com , but, Dan says he wrote the original code 15 years ago... There's more than one way to grow a tree!

Wow, thanks for the interest in EZ-Tree everyone! Made a few quick updates for v1.0.1 1) Had Claude optimize assets, reduced bundle size by 60% (still need to generate a barebones version without assets embedded in it) 2) Replace old debug controls with a custom UI FYI, EZ-Tree is also available as an npm package @dgreenheck/ez-tree" target="_blank" rel="nofollow noopener">npmjs.com/package/@dgree…

@dangreenheck @acolytealch Nice! Fair enough

@acolytealch @danielacorner I wrote the core generation code 15 years ago in college. AI was used for porting from C# to JS.

I was tired of hunting for good looking tree assets that didn't cost a fortune, so I decided to make a tool to generate my own. 50+ parameters, direct export to GLB, 100% free. Try it out 👉🏻 eztree.dev

@acolytealch @dangreenheck Evident Lee

@danielacorner @dangreenheck He used AI, problably it took a bunch of reference from florasynth.com.

ok which one of you is ready to make an Age of Empires 2 like interface for Claude Code and make a billion dollars??

@Mont_Wonky @Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok Just messing with you 😜

@danielacorner @Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok Huh? ? ?

@Mont_Wonky @Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok Got you last mate!

@Mont_Wonky @Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok Reply. Got you last!

@danielacorner @Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok Knob. I just can't take you seriously for using all those f's.

@Mont_Wonky @Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok Fffffffalse en.wikipedia.org/wiki/Debt:_The…

@Aude_Sonia @ChrisMags80 @ChanceGlasco @ennui365 @grok That's how the world works. It's how it's always worked. And it will continue to work that way always. The real question you should be asking is why it's a problem all of a sudden when it comes to Elon. My guess is because he's not in the 'club' The 'club' is the problem.