Hole High

The Reta era has come to an end... Bittersweet moment for sure. 7 months ago I started Reta, in a phase of life that was dramatically different than where I am now. Today, I'm about to look in the mirror and genuinely be happy with what I see. This peptide, among other critical lifestyle changes, has been the backbone of my weight loss journey starting in late 2025. Now that I've reached the body fat and health markers I set out to improve, I've made the decision to switch to low dose tirz, entering a weight management phase. (All of this information is for educational/research purposes only, not medical advice, just my n=1 experience) Overview: - Start (Dec 2025): 215 lbs, ~21% BF (est.), 38" waist - Now (June 10, 2026): 178 lbs, 7.9% BF (Seca), 29.25" waist, VAT <0.2 L Roughly 1.4 lbs/week loss across the full run. More end-point data: - 46% skeletal muscle mass - Grip strength 134.8 lb - Top 1% body-comp on the Seca scan NOTE: Seca percentile scores your full body composition (muscle, fat, fat distribution, visceral fat, fluid balance) and benchmarks it against an age- and sex-matched reference population. I came back in the top 1% of that group. I take that data with a grain of salt, but visually I'd put myself in the 8-10% BF range now. Latest labs (April 2026): - Metabolic: Glucose 70, fasting insulin 3.0, A1c 4.9 - Lipids: HDL 49, TG 42 (1:1 with HDL), LDL 69, ApoB 56 (5-10th percentile), Lp(a) <10, CRP 0.4 Now the full picture. I want to be transparent about every lever I was pulling through this process. This was not a Reta clinic trial. It was one piece of a full biohacking protocol. Hormones and peptides: - Retatrutide: 2mg start, ran 1.5-2.5mg/wk (Dec 2025 to now) - Testosterone (TRT base): 200mg/wk, dropped to 180mg/wk mid-run - HCG: 500 IU 2x/wk throughout - Tadalafil: 6mg, 3x/wk through the run, daily now - Anastrozole (AI): dropped April - CJC-1295 / Ipamorelin: cycled - Tesamorelin: short block (3 weeks) - MT2: off and on (inconsistent) - SS-31: added late May - MOTS-c: added late May - GLOW: added late May Supplements: creatine, omega-3, CoQ10, vitamin C, DHEA, magnesium bisglycinate, glycine, NAC, TUDCA, pregnenolone, thyroid support, B-complex, taurine, L-theanine. Positive benefits I noticed: - More focused - The most energy I've felt in a calorie deficit - Most successful weight loss phase in my life - Lost desire for alcohol and THC - Less pull toward cheap-dopamine habits (gambling, mindless scrolling, video games) - Less desire for junk food (except cookies) Negative observations: - Increase in RHR (mid-50s to low-70s) - Decreased sleep quality - Forgetting to eat - A flat, apathetic mood when I pushed the dose to 2.5mg - Decrease of interest in hobbies Why I'm switching: The fat-loss goal has been accomplished. I am now switching to into a weight management/optimization phase. Even on low dose reta (1mg), I still have the RHR and sleep quality issues. So I am going to be transitioning into an experiment with low dose Tirz to see if I see improvements on these markers. What's next: - Hold 178-180 through the summer, then a lean bulk around the holidays - Keep dialing caffeine and nicotine down - Improve sleep and RHR - Shift focus to maintenance, muscle gain, and optimization in and out of the gym This chapter was the backbone of the biggest change I've made to my body and lifestyle. I'm closing it grateful and more locked in than ever on what comes next. I am sure that I will look back at this experiment with a bit of nostalgia at some point. Thank you to everyone who's been following my biohacking/peptide journey. We're up to 2,770 followers now and it's just unreal how supportive and awesome the X community is. I have learned so much from engaging with people on this platform and want to continue to grow alongside everyone else following a similar journey.🦾

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