Lindsay Karaba

How does the hippocampus moderate reactivation following learning? We identified a hippocampal circuit mechanism which seems to play this role- and it’s driven by CA2! Check below for a summary of our recent results from this week's @ScienceMagazine science.org/doi/10.1126/sc… 1/

🚨 Our paper is finally online! 🚨 🖥️🐭 Are you a head-fixed VR user? Interested in integrating VR and eye tracking into your setup? Check this out! 👀💡 🔍 Don’t miss it! 🙌 #VR #Research #neuroscience

Looking forward to meet everybody and enjoy the science once again this #SfN24 ! The lab is presenting several posters, most of them on Sunday afternoon. Stop by to chat, check out what we have been up to this year and meet our amazing students and postdocs 🤩

Happy have made a small contribution to this exciting study on the neural circuit mechanisms mediating anxiolytic effects of serotonergic psychedelics. With @karaba08!

@Yashiro_Isana_X @ScienceMagazine Glad you enjoyed! Because this is in mice it's hard to know if it has a connection with dreams, but we see neural patterns that were active in wake recurring in non-REM sleep in sharp-wave ripples, which supports memory consolidation. You might find this literature interesting!

@karaba08 @ScienceMagazine I'm always super fascinated by science like this, especially when I read the article. So, would dreams more or less be a way your brain stores action as a memory? I likely don't know nearly enough on the subject. But another curiosity is what's happening when you lucid dream?

How does the hippocampus moderate reactivation following learning? We identified a hippocampal circuit mechanism which seems to play this role- and it’s driven by CA2! Check below for a summary of our recent results from this week's @ScienceMagazine science.org/doi/10.1126/sc… 1/

@Ella_Maru @ScienceMagazine Thanks, Ella! Great question. Short answer is we don't know, but potentially! Because we see specific modulation of task-relevant cells within BARRs, it's certainly possible that they also play a role in helping prioritize what information is maintained vs forgotten.

@karaba08 @ScienceMagazine Congrats, Lindsay! Could BARRs play a role in selective memory weakening or forgetting, particularly for less relevant information?

And to close, I'll leave you with some early concept art from AYA Lab's very own @hongyu_chang 💕 15/15

With that, I want to give a HUGE shoutout to my co-first author @heathlarsson, PIs @azayhara and @antferrui, and additional authors @ryaneharvey and @YYC356. This wouldn’t have been possible without them and their unmatched passion for rigorous science and cool results. 14/