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10.9K posts

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@9dbfg

Business nerd | Mobile dev nerd | Orlando fanboi | MBA

Присоединился Temmuz 2012
157 Подписки97 Подписчики
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tart@9dbfg·
I don't belive I used a capital "E" in "engineer", and if I did, that was a mistake. I am using it as a verb, to describe what they are doing, not as a title. Whether or not the profession, or the people who practice it, are noble, is a different conversation.
Gavin (Owner 67 Designs)@67Designs

Ladies and gentlemen, allow me to be perfectly clear and unequivocal on this point: Unless, at the very minimum, an individual possesses a formal engineering degree from an accredited institution of higher learning, they are not, I repeat, not trained engineers. They are, at best, technicians. At worst, they are gamesmen and wordsmiths—adept at navigating systems, but wholly unqualified to hold themselves out as members of the engineering profession. And let us speak candidly about the singular anomaly that is the legal profession: it appears to be the only calling that deliberately trains its practitioners in the arts of reward-seeking through systematic cheating, lying, and deception—all artfully repackaged and dignified under the noble banner of “advocacy.” The profession trains its initiates, year after year, to zealously represent liars, cheats, counterfeiters, and outright criminals, provided only that the currency flows in the proper direction. It is a profession that has institutionalized the transactional defense of the indefensible, all while maintaining the outward trappings of ethics and justice. That, Your Honor, is the unvarnished reality.

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tart@9dbfg·
It's not that the sky is falling, or you should be a pepper, but you should be aware of the world around you.
Ryan Fedasiuk@RyanFedasiuk

“Uhhh…I have to go,” I stammered to a group of @HudsonInstitute staff before collecting my bag and racing off into the pouring rain. It was a Friday evening in Washington. I had been spending it like any other 27-year-old—drinking a Modelo and nerding out about critical mineral supply chains. But my time at our gathering was cut fatefully short by a call from the FBI: I had been targeted in a sophisticated breach from a state actor. What happened over the next four days was a preview into what our world might soon look like after @AnthropicAI's Mythos. The time to prepare is now. choosingvictory.com/p/practical-ad…

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Ryan Deiss
Ryan Deiss@ryandeiss·
If a time machine dropped me back into my first day as CEO, before I nearly lost everything twice, here's what I'd do differently: 1. I'd stop trying to be the best employee in my own company. The more valuable you are to your business, the less valuable your business is. 2. I'd build it like I was going to sell it, even if I never planned to. A sellable business is just a business that runs without you. 3. I'd install an operating system before I hired an operator, integrator, COO, or whatever you want to call them. No operating system, no operator. I learned that one the expensive way. 4. I'd document the 10-20 things that actually matter in my value creation process. Not 500 SOPs that nobody reads. Just the critical few. 5. I'd remind myself every single day that the goal isn't to build a team of rockstars. The goal is to build a company that doesn't require them. 6. I'd build a scorecard that mirrored and tracked the customer journey. Chasing vanity metrics has cost me a small fortune. 7. I'd set a 3-year target and execute in 90-day sprints. Annual planning is just New Year's resolutions for business owners. 8. I'd stop hiring "helpers" and start hiring functional leaders who own outcomes. Helpers make you busier. Leaders make you wealthier. 9. I'd fix my margins before I chased revenue growth. P&Ls lie. Cash doesn't. 10. I'd stop confusing a full calendar with a productive day. Busy isn't a strategy. 11. I'd stop swooping in to "save" things. Every rescue teaches your team to wait for you next time. 12. I'd resist the urge to start something new every time something old got hard. Complex breaks. Simple scales. 13. I'd fire problem clients (and problem business ideas) faster. They always cost more than they pay. 14. I'd have the hard conversations 6 months sooner. They never get easier, but the damage always gets worse. 15. And I'd remember that my kids don't want my money… they want my calendar. I didn't know any of this on Day 1. I learned it all the hard way. But you don't have to.
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Aakash Gupta
Aakash Gupta@aakashgupta·
The company behind this pill has raised $250 million and is running the largest clinical trial in veterinary history, and the science explains why investors are losing their minds. The drug is LOY-002, made by a company called Loyal. It works as a caloric restriction mimetic. It tricks the dog's metabolism into behaving like it's on a restricted diet without actually reducing food intake. The biological cascade this triggers is the same one that's extended lifespan in every species ever tested, from yeast to primates. The FDA has already accepted the safety data and the effectiveness data. Two of three regulatory gates cleared. The third is manufacturing review, expected to complete this year. If approved, LOY-002 becomes the first FDA-approved drug for lifespan extension in any species. Not disease treatment. Not symptom management. Lifespan extension as a formal indication. The STAY study has 1,300 dogs enrolled across 70 vet clinics. Half get the pill, half get placebo. Both beef-flavored so nobody can tell the difference. It is the largest clinical trial ever conducted in veterinary medicine. Here's where it gets interesting for humans. Dogs develop the same age-related diseases we do: cancer, heart disease, kidney failure, cognitive decline resembling dementia. They live in our houses, eat similar food, breathe the same air. A mouse in a sterile lab tells you almost nothing about human aging. A golden retriever sleeping on your couch tells you a lot. Loyal has a second drug, LOY-001, targeting large breeds specifically. Big dogs die younger because centuries of breeding for size accidentally gave them elevated IGF-1 levels, which is the same growth hormone pathway linked to accelerated aging in humans. Reducing IGF-1 in flies, worms, and rodents extends lifespan. Loyal is now testing whether the same holds in dogs. 90 million pet dogs in 60 million US households. Average spending: $1,852 per pet per year. A pill that gives you two more years with your dog is the easiest sell in pharmaceutical history. Human longevity trials would cost $1 billion+ and take decades. Dog trials cost a fraction and produce data in years. Every dog in the STAY study is generating aging data that maps to human biology. The shortest path to an FDA-approved human longevity drug might run through your veterinarian's office.
Pubity@pubity

Scientists have developed a pill that can extend the lifespan of dogs by literal years, and they're pushing to get it on the market by 2027. It's a daily, beef-flavored medication made specifically for senior dogs to keep them healthy as they age.

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Scott Gustin
Scott Gustin@ScottGustin·
NEW: Disney is reportedly planning to cut up to 1,000 positions in the coming weeks, with many of the cuts in the recently consolidated marketing division as part of a cost-cutting effort code-named “Project Imagine," according to @JBFlint and @benfritz. wsj.com/business/media…
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tart@9dbfg·
The suburbs, but with chickens.
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tart@9dbfg·
I don't know that giving Iran's leadership two weeks to catch their collective breaths is a wise move. Not that I'm at all happy that the USA's behavior. I just think once you start something, you gotta go all-out until it's done, all the while making your other adversaries wonder just how crazy and capable you really are.
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tart@9dbfg·
@Just_Curius Also discussed, with great alarm, by a number of nerds, who also recognize that the achievement will surely be duplicated by less-responsible parties, any minute now, especially since Claude suffered a source leak, recently.
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Just Curious / @belikewater
Interesting take
Tenobrus@tenobrus

maybe this is not yet clear, so let me state it plainly: as of right now Anthropic, and really a small number of individuals at Anthropic, has the capacity to directly attack and cause major damage to the United States Government, China, and generally global superpowers. government agencies like the NSA do not have internal models or defense capabilities that outclass frontier models. if they chose to do so, they could likely exfiltrate top secret information from government systems, gain control over critical infrastructure including military infrastructure, sabotage or modify communications between members of government at the highest level, and potentially carry on activities for some time without detection. the thing about having access to a huge number of zerodays your adversaries don't know about is it gives you a massive asymmetric advantage. they did not exploit this to gain power or destabilize the world order. they publicly released the information that they had these capabilities and worked to mitigate these flaws. you should be grateful american frontier labs have proven themselves remarkably trustworthy and concerned with the public good. but it's critical you understand we are in a new regime. private entities now have power that directly rivals and impacts the government's monopoly on influence and violence. and anthropic is certainly not the only one, there's little chance OpenAI's internal models are far behind. this trend will accelerate on virtually every dimension, not slow down. my prediction for how it plays out is the relatively imminent seizure and nationalization of labs by the US government, sometime over the next two years. it's very tough for me to see how they accept the existence of this kind of threat. but this adds a whole new class of governance issues, as then we've handed these extremely wide-reaching capabilities from private entities to public ones.

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MisplacedMagnolia
MisplacedMagnolia@SandraMorefiel1·
@StatisticUrban Americans measure in Freedom Units. Calibers. Blast radius. Penetration. Mach.
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Hunter📈🌈📊
Hunter📈🌈📊@StatisticUrban·
It's insane to me that most Americans can't even comprehend metric units and Celsius without converting. I understand it's not the system used, but it IS the international system, used in all scientific fields and ~every other country. Useful to at least instill the basics.
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bioreconstruct
bioreconstruct@bioreconstruct·
Monorail Teal spotted yesterday afternoon being tugged after a breakdown. Look close. Guests aboard. Many door windows removed for ventilation. @Blog_Mickey has an article describing this more: blogmickey.com/2026/04/monora…
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tart@9dbfg·
@luke_pighetti I feel like liquid death has something to say, since it's devodkinated vodka
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Gurwinder
Gurwinder@G_S_Bhogal·
A 7 year investigation of social science research found that only 1/2 of results could be replicated, and only 1/8 of data analyses could be reproduced. It’s now wiser to assume a social science study is flawed until there’s reason to believe otherwise. nature.com/articles/d4158…
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Disney D23
Disney D23@DisneyD23·
@SethHendrix Sorry you’re having trouble purchasing tickets! For the fastest support, please visit support.d23.com to access helpful resources or connect directly with our D23 Guest Relations team.
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Seth Hendrix
Seth Hendrix@SethHendrix·
Hey @DisneyD23 - your ticketing system sucks. I was put in the queue with 42,000 people ahead of me. I waited patiently for an hour until my turn finally came up. Then the page reloaded, timed out, and kicked me back down to #43145 in the queue again. What the actual hell.
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tart@9dbfg·
Bye @MCO. See ya in a month
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tart@9dbfg·
@SMB_Attorney Welcome to working for yourself. The bad news: work never sleeps. The good news: you get to decide when it naps. Also good news: your kids get to see what bigly adulting is about, and they learn that they can handle it. Also good news: they get a gigantic leg up on their peers.
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