Hahn Lab

Do you like protein engineering, dynamic molecular machines, signaling, microscopy or organic chemistry? We have exciting new projects and are hiring in a number of fields. Please take a look at hahnlab.com/positions.html

5 Minutes That Will Make You Love Bach nytimes.com/2021/11/03/art…

We are excited about a new biosensor technique we just published. Can image single molecule conformational changes within living cells, and can make biosensor engineering substantially easier. authors.elsevier.com/a/1dudAL7PXe-o…

Join me at the discussion at the #cellbio2020 Rho-family GTPases P109 today at 11am about our multidisciplinary work to study #Megakaryocyte and their amazing journey into #platelets

Fired up about our new paper by Marston et al. with 1) a biosensor approach for GEFS 2) simultaneous GEF/GTPase imaging 3) a statistical approach to dissect causality between live cell events. tinyurl.com/y5kygzb9; rdcu.be/b4fhc.

Check out the News and Views on the recent @Hahn_Lab paper by Dean Natwick and Sean Collins. Readable link at rdcu.be/b5MrM. nature.com/articles/s4158…

Our gift to the entire research community: a downloadable database of 314 different types of postdoc fellowships. research.jhu.edu/rdt/funding-op… This file contains detailed info for postdoc fellowships across the natural sciences, engineering, humanities, & social sciences

Ending #ASCBEMBO19 with some great talks! Ben Woods (Amy Gladfelter Lab), Jamie Nosbisch (Jason Haugh Lab), Dan Marston (@Hahn_Lab) and @stephgupton1 all present this morning!

This comes late and after busy couple of months but I'm still super excited! We were awarded at @NikonSmallWorld contest! Special thank you to Shiqiong, Takashi @Hahn_Lab and Jesse @AICjanelia @HHMIJanelia for help and support! I had fun imaging these amazing structures! #nikon

Keith Burridge retires after a distinguished career as professor of cell biology @unc_som! His retirement celebration was a reading of “The Message,” a play that he wrote about the discovery of messenger RNA. @UNC_CBP @ASCBiology @UNC @playmakersrep @Cambridge_Uni @COLDSPRINGHQ

@mattie_rogers Play jazz! Or be in a horn section for a rock band? (Hi)

I wish I learned how to play a practical instrument like the drums or guitar so I could be in a band. I learned the trombone, so instead I can play you all 12 major scales & their arpeggios in under 2 mins how INTERESTING

@koenvddries @AICjanelia HI there. This was a macrophage interacting with micropatterned circles of IgG, showing actin. A good leading ref: Freeman et al., 2016, Cell 164, 128–140.

@Hahn_Lab @AICjanelia Curious for the experimental conditions. Was there some kind of pattern printed on the surface?

iPalm of frustrated phagocytosis, taken by Ana Nogueira and Shiqiong Hu with our good friends at the @AICjanelia.

@dgaboriau @AICjanelia Hi. We believe those are podosome-like structures.

HI there. This was a macrophage interacting with micropatterned circles of IgG, showing actin. A good leading ref: Freeman et al., 2016, Cell 164, 128–140.

"Cell morphological motif detector for high-resolution 3D microscopy images" : biorxiv.org/content/early/… A fruitful and ongoing collaboration with the Danuser lab.

Click Chemistry naturally @nature. Metabolites can be created as precursors to Click reactions using naturally occurring biosynthetic pathways. The introduction of these functional groups opens up the use bioorthogonal chemistries, including Click nature.com/articles/s4158….