Sandra Ribeiro Lab

Published in @JMolBiol: ACCU-RATES – a web tool for accurate Kₘ & Vₘₐₓ from progress curve raw data. No more guessing the 'linear phase'! Fits noisy data robustly. Free to use for #Academia. Paper: doi.org/10.1016/j.jmb.… Try it: accu-rates.i3s.up.pt #EnzymeKinetics

Doença Machado-Joseph: Identificada molécula que pode atrasar sintomas | Antena 1 Açores acores.rtp.pt/radio/doenca-m… @i3S_UPorto

A doença de Machado-Joseph, uma doença neurológica rara, hereditária e degenerativa, apresenta uma prevalência significativa em Portugal e não tem ainda cura nem uma terapia eficaz. publico.pt/2026/01/05/cie…

🚨We look for a Postdoctoral researcher to work in Parkinson’s Disease Immunotherapy 🧠 Join @CaixaResearch funded multidisciplinary project at @UABBarcelona , combining structural biology, protein engineering, immunology & nanotechnology to develop a disease-modifying therapy.

Estas são algumas das imagens da exposição MIDNIGHT ZONE que está patente ao público, no CPF. No dia 14.12.2025 terá a oportunidade de visitar a exposição guiado pela sua autora Mª Constanza Ferreira e participar na Conversa sobre esta mostra. A visita começa às 16h30.

Visita Guiada e Conversa No CPF com Maria Constanza Ferreira, autora da exposição Midnight Zone Foi assim no CPF este domingo, 14.12.2025. #centroportuguesdefotografia #fotografia #midnightzone #exposição

Visita Guiada e Conversa No CPF com Maria Constanza Ferreira, autora da exposição Midnight Zone Foi assim no CPF este domingo, 14.12.2025. #centroportuguesdefotografia #fotografia #midnightzone #exposição

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies - Silva - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

🚀 Interested in large-scale virtual screening using molecular docking? Meet jamdock-suite: github.com/jamanso/jamdoc… a free toolkit that automates the entire workflow including compound library generation and docking analysis. 🧵

The AUUUC repeat RNA aggregates sequester RNA-binding proteins like NOVA2 and lead to iron dyshomeostasis in spinocerebellar ataxia type 37 biorxiv.org/content/10.110…

📢 Very happy to meet my colleagues from Max Planck MPI-Martinsried (Germany), Sandra Macedo & Pedro Pereira PIs in I3S Oporto. Former Prof Robert Huber colleagues are all around the world, a huge structural biologists community that shared an incredible time of discovery ✨️🚀

🚨 Check our new #bioRxiv preprint! Our latest study focuses on pathogenic RNA repeat expansions and introduces a powerful new methodology for studying protein–metal interactions at the nanoscale. 📑biorxiv.org/content/10.110… ...🧶...

• 🔬 Novel synchrotron-based X-ray fluorescence microscopy (SXRFM) method enabling nanoscale protein localization, under near-physiological cryogenic conditions with 20–50 nm resolution, while simultaneously mapping 15+ trace elements’ distribution and concentration.

I’m feeling grateful to have taken part in the latest Gordon Research Conference on CAG Triplet Repeat Disorders and honored to have received a Speaker Award! Huge thank you to everyone who made this possible: the team and collaborators I have the privilege to work with :)

Celebrating the 10th Biophysics Week (March 24th-28th), we revisit the exhibition "Um Olhar Raro" at ICBAS- Abel Salazar Institute of Biomedical Sciences. @BiophysicalSoc @ICBAS_UPorto @i3S_UPorto @EU_Commission #Biophysicsweek #rarediseases #PhasAGE #PYBphy

meetings.embo.org/event/25-struc… #EMBOStructuralBio

Today is #RareDiseaseDay which is meant to bring awareness to rare diseases around the world, including the various types of #Ataxia! How are you championing Rare Disease Day today? For more information on Rare Disease Day, visit: rarediseaseday.org

⌛️Only 7 days left! The abstract submission deadline for #ML4NGP2025 is March 3! Don't miss this opportunity to engage with our keynote speakers in Vilnius! Submit your abstract today: ml4ngp.eu/conference-vil… #MachineLearning #Protein #abstractsubmission

Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies biorxiv.org/content/10.110…

Allosteric modulation of ataxin-3 aggregation and potential therapeutic strategies for Machado-Joseph disease. The power of teamwork to tackle complex biological questions! 👉biorxiv.org/content/10.110… #Neurodegeneration #Ataxin3 #Allostery #ProteinAggregation #Preprint