Structure

Online now! prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation dlvr.it/TRc9Wm

Online now! CAND1 and CAND2 drive CUL4 substrate receptor exchange with largely comparable biochemical efficiency, unlike their relative effects on CUL1 dlvr.it/TRc1r5

Online now! Human GlyRα2 pore dynamics in gating and inhibition dlvr.it/TRYvLq

Online now! Bending the rules: Histone variants rewire chromatin repression in trypanosomes dlvr.it/TRXylX

Online now! Off-target reactivity in clinical monoclonal antibodies dlvr.it/TRXpHc

Online now! Structural mechanisms for the recruitment of factor H by Streptococcus pyogenes dlvr.it/TRWjfb

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Online now! Unrefined ligand occupancy masks protein-binding site heterogeneity dlvr.it/TRR8ZY

Online now! Molecular mechanism underlying the specific RNA recognition of mitochondrial helicase DDX28 and its critical role in mitoribosomal biogenesis dlvr.it/TRR2lv

Online now! Ligand-specific conformational dynamics of the α2A-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry dlvr.it/TRQtVd

Online now! Coiled-coil-mediated phase separation of Spef1 for central-pair microtubule organization and function dlvr.it/TRQh0z

Online now! Structural characterization of the Cu(II)-NTA spin label on α-helices by X-ray crystallography and electron paramagnetic resonance dlvr.it/TRQ9Xh

AlphaFold3 turns the H1 dual importin system upside-down dlvr.it/TRQ1Qd

A bis-phosphorylated peptide wrangles the SHP2 tandem SH2 domains into shape dlvr.it/TRPvpY

Shrinking a bottleneck in cryo-EM sample preparation dlvr.it/TRPlRS

Meet the author: Kevin Corbett dlvr.it/TRPXxC

A shared amyloid fold in cardiac fibrils from three neuropathy-associated ATTR variants dlvr.it/TRP2TG

Discovery of tankyrase scaffolding inhibitor specifically targeting the ARC4 peptide binding domain dlvr.it/TRNtTp

Time-resolved X-ray solution scattering observations of light-induced structural changes in sensory rhodopsin II dlvr.it/TRNmqF

Alphafold 3-guided insights into the Importinβ: Importin7 heterodimer interaction and its binding to histone H1 dlvr.it/TRNcdd