Science Advances

Twirlbot presents a promising route toward the next generation of untethered, self-sustained robotics. Learn more in this week’s issue of Science Advances: scim.ag/4cVcrHV

Researchers have identified a number of effector proteins, molecules secreted by fungal pathogens that can modulate and subvert plant immunity, that likely came from ancient antimicrobials and were repurposed by fungi during coevolution. scim.ag/4n25ARq

A new study finds volcanic eruptions—not an extraterrestrial impact—chilled Earth 12,900 years ago. scim.ag/3QUafcg

When predicting extreme weather, new research finds that a state-of-the-art physics forecasting system still outperforms #AI models. scim.ag/4tEQdkt

Made with a glucose-responsive hydrogel, the ARMPatch changes microneedle length in response to glucose fluctuations. A standard ultrasound probe can then read the changes, providing minimally invasive continuous glucose monitoring. scim.ag/4dg58f7

Researchers have mapped how the threshold for nitrogen delivery to China’s surface water has changed from 1980 to 2020. scim.ag/3Pft1dE

A new study characterizes how wildfire smoke–based ozone has contributed to premature mortality in the U.S. from 2006 to 2023. scim.ag/4n2YegL

🎉 Excited to share my friend & colleague @NihalOlcay's new paper on genetically engineered human cell-based microrobots for selective cancer cell killing—now out in @ScienceAdvances! 🤖🧬 Unlike conventional microrobots that rely only on physical targeting, these living systems combine magnetic guidance with biological specificity—secreting tumor-targeting proteins to eliminate cancer cells while sparing healthy tissue. A step toward smarter, more precise cancer therapies. 🎯 science.org/doi/10.1126/sc…

Researchers have developed a compact, stretchable thumb sleeve that tracks gestures for human-computer interaction. The sleeve can freely switch between tasks like typing and online shopping. scim.ag/4cOdEAW

🚨 Paper out now in #ScienceAdvances @ScienceMagazine 🌱🦠 Pathogens don’t just target protein degradation—they also hijack host translation. "Bacteria use P-body condensates to attenuate host translation during infection" ⚖️♻️ science.org/doi/10.1126/sc…

🚨BREAKING NEWS 🚨 The latest paper from @GenomeFun Lab is now published in @ScienceAdvances! Developed at @CBM_CSIC_UAM, this study uncovers an unexpected link between transcription kinetics and cell plasticity. 🔗 science.org/doi/10.1126/sc…

The protein Adissp is a promising therapeutic agent for diabetes and cardiometabolic disease. Adissp reduces glucose levels without insulin signaling or appetite suppression by mimicking cold exposure, which enhances glucose uptake. scim.ag/4vLeg2K

🚨📢 How do mechanical forces shape a developing organ? Our new @ScienceAdvances study, led by the amazing @CVagenaPantoula, reveals a Piezo1-driven hydraulic mechanism, where mechanical cues control cell volume to guide cardiac formation ❤️🐟 #DevBio 🔗 science.org/doi/10.1126/sc…

Researchers demonstrate an alternative approach for treating HIV in mice by engineering T cells with synthetic receptors that target PD-1, an immunological biomarker of the HIV reservoir. @YannickDaMuller scim.ag/4cF3ySO

A new flood risk map framework can evaluate flood damages, ranking New York City and New Orleans at particularly high risk. scim.ag/41LusU3

ArchesWeatherGen, a weather model based on machine learning, makes highly accurate weather forecasts with a range of likely scenarios, including extreme events, for a much lower cost. scim.ag/4cZJcEZ

Malaria substantially influenced early human dispersal across Africa—and long before crop domestication began—according to a new study. Learn more on #WorldMalariaDay: scim.ag/41KwCmR

Tomatoes lose their bitterness and toxicity as they ripen thanks to DNA demethylation, the hormone ethylene, and key transcription factors, according to a 2025 study. Learn more: scim.ag/4gNAclb #DNADay

New analyses of baby teeth reveal when the infant brain is especially susceptible to neuroactive metal exposure. scim.ag/41KNVEi

New research finds that the active volcano Methana near Athens, Greece, once slept for nearly 110,000 years—complicating the classic understanding of volcanic dormancy versus extinction. scim.ag/3Qmk7vi