The ideal profile he is looking for is someone who can combine data from multiple structural biology approaches (ET, EM, HDX-MS,…) and, based on these insights, perform rational protein design. (2/2)
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Boudker Lab
280 posts
Boudker Lab
@BoudkerLab
We study the mechanism, energetics, and evolution of glutamate transporters. Account run by lab members. @WeillCornell @HHMINEWS
New York, NY Sumali Eylül 2020
399 Sinusundan964 Mga Tagasunod
A former lab member, Gerard Huysmans, now at GSK in Belgium, is hiring a Principal Scientist specializing in Biophysics and Structural Bioinformatics. Here is the link to the detailed job description:
jobs.gsk.com/en-be/jobs/406… (1/2)
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Boudker Lab nag-retweet
Excited to share that the first manuscript from my independent lab, which details the activation mechanisms of the phosphate exporter XPR1 by the signaling molecule InsP8, is now available in preprint.
biorxiv.org/content/10.110…
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Boudker Lab nag-retweet
We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (biorxiv.org/content/10.110…)!
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Boudker Lab nag-retweet
I am deeply honored to receive the 2025 Kazuhiko Kinosita Award in Single-Molecule Biophysics from the Biophysical Society. Our achievements build on the foundations laid by many great scientists, including all past recipients of this award. I would like to extend my sincere gratitude to the Biophysical Society and the award committee for recognizing our team’s contributions. I also thank my scientific mentors, the colleagues with whom I’ve had the opportunity to collaborate, and the many talented young scientists whose dedication brought our research to fruition. Special thanks must also go to the leadership at St. Jude Children’s Research Hospital for their vision to create a center for single-molecule imaging, enabling us and others at our institution to dig deeper into the roles of structural dynamics in complex biological systems to disease. The future of single-molecule biophysics is brighter than ever, and I hope our contributions will inspire the next generation of scientists.
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We could say more, like “he will be missed” and “stay tuned for great science coming out of his lab”, but considering who still runs this Twitter account, it would feel a bit like…
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Congratulations to our very own @firewhenreddy on starting his own group at USF in January 2025!
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@BiaoQiu1 Check out the never seen before "semi-open" state, with L-Cys bound but before the last sodium ion (Na2) binds and closes the gate.
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Is it substrate? In our preprint led by @BiaoQiu1, we comprehensively assess EAAT3 substrate recognition properties using DSF, SSM ephys, and cryoEM. The L-Cys bound structure suggests that sodium binding is the final step of gate closure. Read below!
biorxiv.org/content/10.110…
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Boudker Lab nag-retweet
We are a soliciting nominations for the 2025 Kenneth S. Cole Award given to one or more researchers in the field of membrane biophysics in acknowledgment of their exceptional research accomplishments, potential for future contributions, and service to the biophysics community.
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Boudker Lab nag-retweet
Two open fully funded Postdoc positions in my lab in #cryoEM & #cryoET. See description below 👇Please share and spread the word. For all those interested in joining my group and work on exciting and collaborative projects please apply!
drive.google.com/file/d/1Qs4roS…
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Boudker Lab nag-retweet
Here we go! Our structure of the human dopamine transporter in complex with cocaine has been published in Nature (nature.com/articles/s4158…). Commentary by @SitteHarald (nature.com/articles/d4158…). Thanks to @ShahsavarAzadeh and Pape for contributing. @neuroscience_dk, @UCPH_health
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Boudker Lab nag-retweet
Pls RT📢We are hiring! Join the @HHMINEWS Science Department as a Scientific Officer. This is perfect for you if you have been running a lab for 7+ years and would like to broaden your impact in science. Help us administer the #HHMIInvestigators #FHScholars #HannaGrayFellows programs and move science forward
-Remote work eligible
-Keep your lab - HHMI provides research support
hhmi.wd1.myworkdayjobs.com/External/job/H…
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Boudker Lab nag-retweet
Postdoctoral position in computational biophysics, machine learning, and structural biology is open! Please see details in the attached.
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Boudker Lab nag-retweet
nature.com/articles/s4158…
Great work by Elizabeth Kim (@lizdkim) and Xiaoan Wu! Collaboration with teams of Peter Larsson (Linkoping University), Alessio Accardi (@accardilab) and Peter Goldstein @WeillCornell @WCMAnesthesia.
Free link: rdcu.be/dPAy1
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Boudker Lab nag-retweet
Excited to share our Annual Reviews in Biophysics article on Single-Molecule Imaging of Integral Membrane Protein Dynamics and Function. Many thanks to all authors for their diligence putting this summary overview together! pubmed.ncbi.nlm.nih.gov/39013028/
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Boudker Lab nag-retweet
Recovering true FRET efficiencies from smFRET investigations requires triplet state mitigation pubmed.ncbi.nlm.nih.gov/38877317/
Grateful for the rigorous and tireless efforts from all authors of this work. Thankful to the Editor and Referees for helping us refine the take home messages!
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