A. Sarah Erem

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A. Sarah Erem

A. Sarah Erem

@CakePath

You have power over your mind – not outside events. Realize this and you will find strength by M. Aurelius about COVID. Dermpath25 @ColumbiaDerm @EmoryPathology

Atlanta Sumali Mart 2020
231 Sinusundan705 Mga Tagasunod
A. Sarah Erem
A. Sarah Erem@CakePath·
Let’s start the morning with pressure lesions! This one is rare but worth knowing—it's much more common on the ear. 🛌Chondrodermatitis Nodularis Nasi (CNN): 👃 Painful, tender small nodule on the nasal tip/ala ⚠️ Central ulcer with wedge-shaped dermal ischemic degeneration 🧩 Underlying degenerative cartilage-chondrocyte dropout/fissuring 🔄 Pressure-induced ischemic repair pattern with granulation tissue — histologically identical to Chondrodermatitis nodularis helicis #dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #PathTwitter
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A. Sarah Erem
A. Sarah Erem@CakePath·
🔬 Perivascular Myoid Tumors: SMA+, desmin-, caldesmon- 👉 fake smooth muscle tumors! 1.Biphasic pattern + hemangiopericytoma-like vessels➡️Myofibroma (image attached 👇) 2.Concentric perivascular wrapping without zonation Uniform onion-skin architecture ➡️ Myopericytoma 🔬🔬True smooth muscle differentiation: SMA+, desmin+, caldesmon+ Think "Thick"-walled muscular vessels ➡️Angioleiomyoma #dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #pathTwitter
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A. Sarah Erem
A. Sarah Erem@CakePath·
🔬 Myopericytoma 🫡Typically presents as a well-circumscribed dermal/subcutaneous nodule 🩸Characteristic perivascular concentric (“onion-skin”) growth around thin-walled vessels 🤥Not a true smooth muscle tumor (unlike angioleiomyoma) 🪴Bland cytology in benign lesions 🧠 Dxx ➡️ Angioleiomyoma — Fascicular smooth muscle bundles, thicker vessel walls, diffusely desmin-positive ➡️ Glomus tumor — Uniform round cells, no concentric spindle growth ➡️ Myofibroma — Biphasic pattern with zonation #dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #pathTwitter
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A. Sarah Erem
A. Sarah Erem@CakePath·
🧵Collagenous Dermatofibroma 🌳 Epidermal induction with overlying acanthosis and basal hyperpigmentation 🌀 Poorly cellular interlacing spindle and histiocytic proliferation in the dermis 🧵 Prominent dense, hyalinized (sclerotic) collagen replacing much of the storiform architecture 🎯 Peripheral collagen trapping with entrapment of thickened dermal collagen bundles 🧫 Occasional peripheral reactive lymphoid aggregates #dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #pathTwitter WSI: aisight.pathai.com/unaffiliated/s…
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A. Sarah Erem
A. Sarah Erem@CakePath·
Happy Saturday 😊 - Macular amyloidosis! 🩺 Rippled hyperpigmented macules (often pruritic) on upper back/extensor arms; associated with chronic friction. 🔬 Scant papillary dermal amyloid with basal hyperpigmentation ± pigment incontinence; minimal inflammation. 🧪 Ancillary: Congo red+ (often weak), PAS+, ± Thioflavin T; keratinocyte-derived amyloid, not AL/AA → no systemic amyloidosis. #dermresident #pathresident #pathTwitter #dermpath #dermatology #dermatologia #dermtwitter
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A. Sarah Erem
A. Sarah Erem@CakePath·
@redsnapperpath Nice to see you, Dr. Osmond! Hope you are rocking the Dermpath!!! Come to USCAP!!!
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A. Sarah Erem
A. Sarah Erem@CakePath·
@JMGardnerMD you may also have LS starting out in that papillar/superficial dermis of yours 😇☺️🙃
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Jose Candido
Jose Candido@JCandidoXavier·
Not every cystic invagination of the epidermis represents an epidermoid cyst. 😬 Tiny pilar sheath acanthoma: note the crater filled with keratin and the solid lobules of eosinophilic cells radiating from it. #path #pathology #dermpath #dermatology
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