frederic.relaix

New! Online now: Endothelial metabolic control of insulin sensitivity through resident macrophages dlvr.it/TD8h7M

Researchers at @UPFBarcelona, together with teams of scientists from China, the USA and Spain, produced comprehensive atlas of human skeletal muscle aging! Check it out in @nature! 🔬 go.nature.com/44g33d6 🗞️ bit.ly/4dbzdL1

📣Last chance alert! TODAY is the last day to register for the SMB Muscle Stem Cells in Development, Regeneration & Adaptation conference at the reduced rate. Secure your spot today to learn abt the groundbreaking work of Keynote Speaker Dr. Fabio Rossi! 💪

Such a pleasure to meet friends and colleagues from @Telethon_France during the amazing 4th international meeting of @SMAEurope @FRelaix @RelaixLab @Inst_Myologie @PieraSmeriglio @IStemFrance @GenethonFr

Really cool paper! Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion One for you @doug_millay @KevinMurachPhD nature.com/articles/s4159…

Mark your calendars for Oct. 11 as @FRelaix of @UPECactus presents, "Muscle Stem Cells: From Development to Tissue Repair" in Boyer Hall 159. This #ResearchSeminar is open to all UCLA faculty, students and staff!

New #CellDeathDisease paper: KLF4 regulates skeletal muscle development and regeneration by directly targeting P57 and Myomixer. tinyurl.com/47625tr9

My lab has recently moved to the University of Ottawa, Canada. We are hiring PhD students and postdoctoral fellows to study the interaction between muscle stem and niche cells in development and disease. If interested, please send your CV to vsoleima@uottawa.ca. Please RT.

If you want to know more about me, please look at this interview as a "First person" of JCS for my paper entitled "Glucose oxidation drives trunk neural crest cell development and Fate" 🥳

I'm delighted to share the first part of my PhD project now published at @J_Cell_Sci🥳. We studied the impact of the metabolism on Neural crest cell (NCC) development and depicted two different metabolic phenotypes between Trunk and Cranial NCC.@FRelaix @RelaixLab

Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration …eletalmusclejournal.biomedcentral.com/articles/10.11…

If you want to know the effect of a perturbation on a tissue do bulk RNAseq not single-cell RNAseq - unless you're asking if that perturbation caused different cells to be represented. Single-cell RNAseq only measures the top 5000 genes. Don't do it just because it's sexy.

Glad to have collaborated on this manuscript showing decreased dystrophin expression in immune-mediated necrotizing myopathy, which could lead to potential diagnostic pitfall. link.springer.com/article/10.100…

Targeting NAD+: is it a common strategy to delay heart aging? nature.com/articles/s4142…

#NatMetabPicks | In @Nature led by @DrGregSteinberg (@McMasterU): GDF15 treatment in mice counteracts compensatory reductions in energy expenditure, resulting in greater #weightloss and reductions in #NAFLD compared to caloric restriction alone. nature.com/articles/s4158…

Our latest:

My crisis management.

On the Titan, five people died on an expensive excursion. Off the coast of Greece, perhaps 500 people fleeing poverty and violence died. The rescue efforts, and the attention paid to each, fueled a debate about the realities of class and ethnicity. nyti.ms/3CLiPjl

Stephenson 2-18 is among the largest known stars. It has an estimated radius of around 2,150 solar radii (1.5×10⁹ kilometres; 10 AU), which would correspond to a volume nearly 10 billion times that of the Sun [source: buff.ly/3nYCNjj] twitter.com/UniversoPic/st…

Great friendly community of @IMLaminopathies 🙏🙏🙏 SO proud to be part of it @BonneGisele @researchmyology @MedecineSU @Inst_Myologie