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HUGODECA
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HUGODECA
@Hugodecaproject
HUGODECA is a H2020 project whose goal is to build the 1st multiscale developmental cell atlas of human gonads and genital tracts to study sex determination🇪🇺
Sumali Mayıs 2020
87 Sinusundan92 Mga Tagasunod
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📢We are hiring 2 #Postdocs to lead new research projects: 1 with expertise in #bioinformatics (#transcriptomics or image analysis) 1 with expertise in hiPSCs and #organoids Funded for 3-5 years.
More information & instructions for application➡️ shorturl.at/sIQU9

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Final version of our 3D map of the human embryo head is out! Cover from Raphael Blain
cell.com/cell/fulltext/…

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It took 4+ years to build this 3D map of the developing human head, the most complex part of our body sciencedirect.com/science/articl…
Tissue clearing #Lightsheet #VirtualReality #3D models & More! Congrats to Raphael Blain, E. Shotar G. Couly @Yorick_Gitton et al. video summary 🔊
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Limb-derived cells help zipping up the mouse penis. nice work from Humphrey Yao's lab @NIEHS
biorxiv.org/content/10.110…

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Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary biorxiv.org/content/10.110…
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Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humans biorxiv.org/content/10.110…

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COUP-TFII regulates early bipotential gonad signaling and commitment to ovarian progenitors biorxiv.org/content/10.110…
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Partial male-to-female reprogramming of mouse fetal testis by Sertoli cell ablation
Read this #OpenAccess Research Article by Kenya Imaimatsu, Ryuji Hiramatsu, Ayako Tomita, Hirotsugu Itabashi & Yoshiakira Kanai @UTokyo_News_en:
journals.biologists.com/dev/article/15…

Eesti
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Taking Volumetric correlated light & EM (vCLEM) to the next level 1)Design 8 recombinant smaller single-chain variable fragments (scFv) able to penetrate 100µm deep w/o detergent 2) confocal microscopy 3) microCT 4) serial EM & registration. Lichtman lab. biorxiv.org/cgi/content/sh…
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Merci à @ZoeVarier et @Anna_LaTac @franceinter pour ce podcast "in utero" sur l’embryon humain qui illustre parfaitement les progrès récents de la recherche et aussi l’étendue de ce qui reste à découvrir sur nos origines
France Inter@franceinter
Découvrez notre nouveau podcast "In Utero" : un voyage sensoriel saisissant, parfois troublant, en compagnie de grands scientifiques français et de @ZoeVarier , aux origines de la vie humaine.
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Excited to announce that "The Multiscale Human" has been selected as one of three new programs as part of @CIFAR_News third Global Call for Ideas, exploring #TheFutureofBeingHuman!
youtu.be/V__0yJbzMKY

YouTube
CIFAR@CIFAR_News
The Multiscale Human seeks to create a ‘Google Maps’ to the human body, collecting information across systems and scales to revolutionize precision medicine and transform our understanding of the human body.
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Want to know more about Human Embryology? Join us for the 1st meeting of the @Inserm HuDeCA project. 23 November 2022 in Paris🇫🇷. Registration is FREE. Speakers include @BrivanlouLab @Etche_homo @PourquieOlivier @VanderhaeghenP2 @maitrejl Elena Cattaneo Mary Herbert & more

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Peritubular macrophages phagocyte remains of undifferentiated spermatogonia in mouse testis biorxiv.org/content/10.110…
GIF
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The 22nd European Testicular Workshop will be held at the Palace de Caux, near the town of Montreux on the Swiss Riviera, June 18-22, 2023. Please mark your calendar and spread the word.
Scientific program and information at
@https://etw2023.org/
@AndronetScience
@EMBO

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Thanks to all our 🇪🇺 partners and labs involved 🇫🇷 @InsermTransfert @Inserm @KeenEyeAI 🇩🇪 @miltenyibiotec 🇩🇰@RegionH 🇸🇪 @scilifelab @KTHuniversity 🇬🇧@sangerinstitute 🇫🇷 @irset_fr @NeuroendoLille @InstVisionParis
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Happy to share this video describing the #H2020 @Hugodecaproject which aims at understanding the cellular and molecular mechanisms of sex differentiation in human embryos. funded by @EU_Commission
youtube.com/watch?v=tpvOjs…

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Thrilled and proud to share that our study on human gonadal development is now out in @nature! Incredible teamwork led by @LuzGarAl, @vlorenzi3 and @ceci_icoresi. A little thread below
Single-cell roadmap of human gonadal development disq.us/t/48z7i8i
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I could not resist and had to show these beautiful embryonic lung models made by @megumi4952 from cleared samples imaged with light-sheet microscopy.
Same scale between the models in the left and right hands. Only 3 weeks of development separate them. #3Dprinting by @BONE_3D
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