Kevin M Knight

A universal allosteric mechanism for G protein activation dlvr.it/Rx6LFr

@LaskerFDN @HenrikDohlman Thanks for the shoutout!

G proteins are critical for many cellular processes. How does the key step—dissociation of the Gα and Gβγ subunits—occur? New research shows that just three amino acids are responsible: Gly-Arg-Glu. #gpcr @HenrikDohlman ow.ly/kusR50DN3sO

@ReidHJOlsen I know this pain

Thank you to everyone involved in this work, and to my committee for their guidance and support.

Congrats to folks from @UNC_PHCO @ReidHJOlsen @UNC_BCBP and many others (sorry don't have twitter handles for all)!

eurekalert.org/pub_releases/2… #healthfacts

Scientists @UNC discover viral barcode that allows gene therapy viral vectors to cross the blood-brain barrier more efficiently: bit.ly/2EPh4mf @UNCMedCenter @UNC_Health_Care Could help create better treatments for brain-related conditions while reducing liver toxicity.

Please RT: I notice lots of labs are ordering individual GPCRs from our PRESTO-Tango resource @addgene If you're ordering more than a few you could probably save $$ and time by ordering the entire kit which is here: addgene.org/kits/roth-gpcr…

NATURE: Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone nature.com/articles/natur…

"If you want a man to keep his head in a crisis, you must give him some training." -Seneca

"Goals achieved with little effort are seldom appreciated and give no personal satisfaction."… instagram.com/p/BdmuxVqnC0O/

"I will get ready and then, perhaps, my chance will come." -John Wooden #morningmeditation… instagram.com/p/BdkKxzPHpzV/

"Do not let what you cannot do interfere with what you can do"- John Wooden #morningmeditation… instagram.com/p/BdhlVhGHlfx/

"Success is never final. Failure is never fatal." -Winston Churchill #morningmeditation… instagram.com/p/Bde_toAHLt9/

"Learn as if you were to live forever; Live as if you were to die tomorrow." -Coach Wooden… instagram.com/p/BdcdoU8HnyU/

Amazing tournament to end 2017 season back in October. #grateful #eevb #backtothegrind @… instagram.com/p/BdVUN-7nHm7/