PlotCitizen

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PlotCitizen

PlotCitizen

@PlotCitizen

Lawyer, Doctor, Unemployed, Mastermind, Musical Enthusiast, Wet, Ironing Man. I'm Very Busy And Important. New Followers Will Be Disappointed.

Sumali Temmuz 2010
1.4K Sinusundan216 Mga Tagasunod
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Anish Moonka
Anish Moonka@anishmoonka·
The research behind this is wild. Your sperm carries a set of instructions that tell your genes when to turn on and off. A Duke University study found that THC rewrites those instructions. The more weed in your system, the bigger the changes. It goes straight for the genes your future embryo needs in its first week of life. I had to read the "day 3 crash" part twice. For the first three days after fertilization, an embryo runs entirely on the mother's DNA. Day 3, the father's genes switch on. If those genes carry cannabis damage, the embryo just stops growing. Fertility doctors see this happen in their labs: embryos that fertilized fine and looked healthy on day 2 go completely still by day 5. Boston University tracked 1,535 couples trying to have a baby. Men who smoked weed once a week or more doubled their partner's miscarriage risk. That number held up even when the woman herself never touched cannabis. And the miscarriages clustered in the first 8 weeks, right when the father's damaged DNA would be doing the most harm. Duke also found that the specific genes THC alters in sperm overlap with genes linked to autism. One of those genes, called DLGAP2, helps brain cells communicate with each other. It was changed in cannabis users' sperm. When researchers bred THC-exposed male rats and checked their offspring, the same altered gene pattern showed up in the pups' brains. The damage crossed a generation. Weed has gotten way stronger over the last 30 years. THC content was about 4% in the 1990s but nearly quadrupled to 15% by 2018, and modern dispensary strains regularly sit at 20-30%. Concentrates go up to 95%. Quitting for about 11 weeks (one full cycle of sperm production) reverses some of the DNA changes. Not all of them. Duke's lead researcher says men should stop at least 6 months before trying for a baby. Half of your kid's genetic blueprint comes from you, and right now, THC is editing that blueprint before conception even happens.
Andrew D. Huberman, Ph.D.@hubermanlab

Cannabis is detrimental to sperm: even if they can fertilize, there can be DNA damage. Many miscarriages and (in the case of IVF) “day 3 crashes” which is when paternal DNA normally kicks in, are cannabis related. Dr Natalie Crawford on the Huberman Lab podcast out now.

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Constantinos
Constantinos@Random_Cypriot·
@SoterisF καλα δλδ ο αλλος εδωσε τοσα να καμει ετσι ωραιο σπιτι που μεσα αλλα που εξω σικκη μεν αν πεσει επεσε ?! πραγματικα τοσο που μας κοφκει σε τουτο τον τοπο εν θαυμα οτι υπαρχουμε ακομα
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cy justice@2026
cy justice@2026@nicolaos1356441·
@SoterisF Όταν η Αρχή που διορίζει τους ελεγκτές είναι η ίδια που ελέγχεται, δημιουργείται ένας φαύλος κύκλος, γνωστός στη νομική και πολιτική επιστήμη ως «το πρόβλημα του φύλακα» (Quis custodiet ipsos custodes? – Ποιος θα φυλάξει τους φύλακες;).
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Robert Scoble
Robert Scoble@Scobleizer·
@EFF Stupid move.
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Matthias Schmidt
Matthias Schmidt@eurofounder·
Perfect European career (female edition): 18 - Begin studies in marketing 20 - Student exchange in Lisbon, have sex with foreign men 23 - Unpaid internship at an NGO 25 - Start Masters degree 27 - First paid position. €1,100/month 29 - Get pregnant after a one night stand with a Dutch tourist 30 - Go on a 5-year maternity leave 35 - Return to work, get promoted under the EU Gender Balance Directive 38 - Burn out. Go on 2-year fully paid mental health break 41 - Return to work, surprised that there is no promotion 42 - File discrimination lawsuit 43 - €180,000 settlement, retire 44 - Write LinkedIn post titled “What It Means To Be A Female Leader In Europe”
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LinaHua
LinaHua@Linahuaa·
I would say there's a 20% chance that the molotov cocktail attack on Sam Altman's house was a FALSE FLAG to play victim after all the damning revelations from @RonanFarrow and the mogging from Anthropic on every dimension. Also, whenever Sam is in trouble he's posting his baby boy. I'm sorry that I have to sound like such a bitch, but the 20% tinfoil hat view happens when someone is constantly lying and gaslighting.
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Marc Carter
Marc Carter@marcadamcarter·
Throwing a Molotov at someone’s house is wrong. Full stop. But there’s a certain irony in asking for de-escalation while shipping the most destabilizing technology in human history at maximum speed. The silver rule cuts both ways: don’t impose on others what you wouldn’t want imposed on you. Maybe start there.
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Aella
Aella@Aella_Girl·
"If a man wants to cum on his girlfriend’s face because he saw it in porn, and she doesn’t feel like getting her face cummed on, we cheer go-girl and frown at the man for even watching porn at all. But if a woman wants her boyfriend to buy her flowers because she grew up being fed this action in movies, and her boyfriend doesn’t feel like it, we have no sympathy for him. We are horrified even at comparing the two things. It’s obvious to us that porn should not influence what happens in sex, but we have been so immersed in romance-porn that the idea of buying flowers for a woman is seen as what romance ought to be. The romance narrative has become romance, and rejecting the narrative becomes rejecting romance itself. We have lost the ability to distinguish!"
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Aakash Gupta
Aakash Gupta@aakashgupta·
Let me explain exactly why Apple still uses drag-to-install in 2026, because the joke here accidentally proves Apple right. A macOS .app is a single self-contained folder disguised as a file. Every dependency, every framework, every resource lives inside it. Drag it to Applications, it works. Drag it to Trash, it's gone. No registry entries. No leftover DLLs. No uninstaller that misses half the files. Windows installers scatter fragments across Program Files, AppData, the registry, system32, and a dozen temp directories. Uninstalling a Windows app is an archaeological dig. Five years later you're still finding config files from software you forgot you owned. Linux is worse. Dependency hell is so common they named it. Entire package managers exist to solve the problem of "I installed something and now nothing else works." Flatpak and Snap were invented specifically to copy what macOS bundles already did natively. The macOS bundle architecture came from NeXTSTEP in 1989. Steve Jobs brought it to OS X in 2001. The core design hasn't changed because the core design was correct. An app is a folder. Installation is a copy. Removal is a delete. Three operations that map perfectly to how humans already think about files. The drag-to-install window with the arrow isn't lazy UX. It's the entire thesis of the system made visible. You are literally just moving a folder. There is no "installation" step because there's nothing to install. The app is already complete. Every other OS eventually tried to get here. Windows got MSIX. Linux got Flatpak. Mobile figured it out from day one because phones shipped after Apple proved the model. The pattern everyone else converged toward is the pattern this tweet is calling outdated. The funniest part: the app being dragged in that screenshot is Claude. An AI that can write code, analyze documents, and reason about complex systems. And the most advanced step in getting it onto your machine is holding down a mouse button and moving your wrist two inches to the right. That's not a design failure. That's a 37-year-old architecture so good that the most sophisticated software on earth still ships inside it.
Noah Cat@Cartidise

it’s 2026 and this is how you install apps on macOS

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PanMetronAriston
PanMetronAriston@PMetron·
@SoterisF Μετά το Κρανς Μοντανά είναι πολιτικά ανορθόδοξο να συζητάμε ως χαμένη ευκαιρία το Σχέδιο Αναν.. Είναι ως εάν να αποδίδουμε ευθύνες για την μη επίλυση του Κυπριακου ,στην Εύα που εκδιώχθηκε από τον παράδεισο.. Ειναι Ως να ψάχνουμε επιχειρήματα στην Κόλαση ,για το χαμένο Παράδεισο!
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Soteris Flourentzos
Soteris Flourentzos@SoterisF·
Είτε Ναι είτε Όχι στο Σχέδιο Ανάν, το θεωρώ ανόητο να εορτάζεται η απόρριψη του ενόσω το Κυπριακό παραμένει άλυτο. Πραγματικά ανόητο, αφού η κατοχή παγιώνεται και οι (πρωτογενείς) πρόσφυγες λιγοστεύουν χρόνο με τον χρόνο.
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Max the VC 👨‍🚀
Max the VC 👨‍🚀@mreiffy·
Google is basically saying: “We’ve cut the quantum resources needed to break Bitcoin’s encryption by 20x. We can now break it. We can prove it. We’re just not going to tell you how. We’ve slowed down research to give crypto a chance. You have until 2029 to figure out a solution. Good luck.”
nic carter@nic_carter

Many are wondering "what Google saw" that caused them to revise their post-quantum cryptography transition deadline to 2029 last week. It was this: research.google/blog/safeguard…

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nic carter
nic carter@nic_carter·
Many are wondering "what Google saw" that caused them to revise their post-quantum cryptography transition deadline to 2029 last week. It was this: research.google/blog/safeguard…
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