Teif Lab

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Teif Lab

Teif Lab

@TeifLab

Teif lab at @uni_of_essex. We work on nucleosomes, chromatin, TFbinding, CTCF, cfDNA. Find us at 🐘 and 🦋. [email protected]; [email protected]

University of Essex, UK Sumali Mart 2019
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Teif Lab
Teif Lab@TeifLab·
Congratulations to Negin Behboodi on successfully passing your PhD viva! We are so proud of you! Keep an eye out for Negin's upcoming big papers! And thank you to the kind examiners @mikhailspivakov and @amarcobio!
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Teif Lab
Teif Lab@TeifLab·
Congratulations to Amishasingh Beeharry for successfully passing the MSD viva! You are the best, Amisha! Thank you very much to the examiners, Abdenour Soufi and Toni Marco!
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Sylvan Baca MD PhD (Hiring!)
Sylvan Baca MD PhD (Hiring!)@SylvanBacaLab·
Much more in the preprint! Looking forward to translational applications to study cancer evolution and guide treatment selection. Grateful to @jberchuck, @manoliskellis, and our other collaborators who made this happen!
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Teif Lab
Teif Lab@TeifLab·
Great to see that this preprint used our software NucTools to calculate NRL, and reached conclusions confirming our previous paper, which reported effect of linker histones H1 on cfDNA fragmentation patterns and nucleosome spacing in cancer tissues/cfDNA link.springer.com/article/10.118…
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Sylvan Baca MD PhD (Hiring!)@SylvanBacaLab

Excited to share our latest preprint by Alexis Yang and Gary Lee, in collab with the @jberchuck lab: biorxiv.org/content/10.110…. We found that transcription of enhancers (a mark of activation) causes distinct fragmentation patterns in #cfDNA.

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Teif Lab
Teif Lab@TeifLab·
Happy to announce that our department (School of Life Sciences at the University of Essex) is upgraded to number 6th out of 91 UK universities in the subject area Biology according to the Guardian University Guide 2026. theguardian.com/education/ng-i…
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Elena Pugacheva
Elena Pugacheva@ElenaPugachev12·
Excited to share our latest study published in Nucleic Acids Research: academic.oup.com/nar/article/53… It’s the cover story for Issue #12! We drew inspiration from Greek mythology to illustrate CTCF’s constant struggle in shaping the 3D genome architecture.
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Teif Lab
Teif Lab@TeifLab·
NHS announced that it will start offering first liquid biopsy tests for diagnostics of lung and breast cancer; also planning expansion to pancreatic and gallbladder cancers england.nhs.uk/2025/05/nhs-fi…
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Teif Lab
Teif Lab@TeifLab·
We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and more jobs.ac.uk/job/DMK060/sen…. Apply by 21st April 2025!
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Teif Lab
Teif Lab@TeifLab·
Very happy to contribute to this paper about cfDNA in SCLC, led by the team of Anish Thomas. It's already online in Genome Medicine: Takahashi et al., Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor genomemedicine.biomedcentral.com/articles/10.11…
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IsabellaC
IsabellaC@isabella_ciu·
2nd time at #FOG2025 (1st time presenting!), it never disappoints!✨ Great talks, groundbreaking research and good times with old&new friends Huge thanks to everyone who stopped by my poster, truly grateful for the interest & discussions Already looking forward to next year!🙌
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Vitalii Kleshchevnikov, PhD
Vitalii Kleshchevnikov, PhD@vitaliikl·
@StevenSalzberg1 @DaveJuergens I agree with the point about impossibility to predict from sequence alone - but it’s a problem with how people communicate what these models do - models that use only DNA sequence as input (like Enformer) introduce sample/cell type-specific latent variables in the last layer.
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Steven Salzberg 💙💛
Steven Salzberg 💙💛@StevenSalzberg1·
Is this real, or is it excessive AI hype? New paper claims that an AI foundation model achieves experimental-level accuracy in predicting gene expression even in previously unseen cell types." I'll read the paper, but don't believe it for a second nature.com/articles/s4158…
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IsabellaC
IsabellaC@isabella_ciu·
Low quality picture but… Had to show the matching glasses 🤭🤓
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Teif Lab@TeifLab

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Teif Lab
Teif Lab@TeifLab·
Interestingly, the BBC coverage attributed this success to NHS testing vans stationed in busy areas where any person can walk-in without referral. Probably technological genomics developments also contributed to this improvement, in any case these are set to help going forward
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Tuklasin

@mikhailspivakov @amarcobio @SylvanBacaLab @jberchuck @manoliskellis @ElenaPugachev12 @EssexLifeSci @vitaliikl