Catarina Homem

Open position for a research assistant/PhD student to work in metabolic and transcriptional regulation of stem cells in Drosophila! Check out more at euraxess.pt/jobs/295466

Interested in doing your PhD in Lisbon, working in neurodevelopment and Drosophila? Our group is looking for candidates to apply for a FCT PhD fellowship! See below for more info and visit our group's page at tinyurl.com/4yf8jh9y. Repost appreciated!

#DBfeature #Drosophila🪰 Opposing effects of ecdysone signaling regulate neuroblast proliferation to ensure coordination of brain and organism development by Andreia Oliveira, Catarina Homem @TheHomemLab sciencedirect.com/science/articl…

In our latest article we demonstrate that Drosophila brain development is under the coordination of the hormone ecdysone. We show that neuroblasts have an intrinsic capacity to proliferate indefinitely and require ecdysone signalling to determine cell cycle pace!

Do you know how animals coordinate the growth of their different organs during development? Systemic signals such as hormones coordinate the development of all organs and direct tissue specific developmental programs.

Our latest article is out ! read it here👇 authors.elsevier.com/sd/article/S00…

Happy #FluorescenceFriday! Eunice Silva, @margarida_venda & @TheHomemLab find that serine hydroxymethyl transferase is required for optic lobe neuroepithelia development in Drosophila. 📖@Dev_Journal: journals.biologists.com/dev/article/15… #DevSImetabolism

Serine hydroxymethyl transferase is required for optic lobe neuroepithelia development in Drosophila An #OpenAccess Research Article in our Stem Cells and Regeneration section of #DevSImetabolism by Eunice Silva, @margarida_venda & @TheHomemLab journals.biologists.com/dev/article/15…

According to our model, the onset of translation is delayed in order to regulate neuronal maturation. Learn more by checking the link in our bio!

In our brand-new article in @PLOSBiology we use Drosophila to show that the transcription and translation of neurotransmitter-associated genes is timely coordinated with the animal’s development.

Our latest article is out ! read it here👇 journals.plos.org/plosbiology/ar…

Within hours of #neuron birth, terminal differentiation genes are transcribed, but not translated. In #PLOSBiology, @TheHomemLab reveals that these transcripts are only translated days later in a way that coordinates with developmental stage in #Drosophila plos.io/3IzWad5

Our postdoc Ana just signed her CEEC contract, granting her funds to pursue her scientific work for the next 6 years! Congrats ! @nova_medschool @fct_pt @NOVAunl

@ERC_Research @HHMINEWS @EMBO @fct_pt @nova_medschool #basicbiology #development #drosophila #metabolism #neurodevelopment

These defects are similar to the defects that are observed when neural tube closure defects occur in human fetuses, and sets important foundations to understand how folic acid works during brain formation.

Check-out our new paper! Serine hydroxymethyl transferase (Shmt) is required for optic lobe neuroepithelia development in Drosophila. tinyurl.com/2rwmrrm8

@ERC_Research @HHMINEWS @EMBO @fct_pt @nova_medschool #basicbiology #CancerResearch #drosophila

Interestingly, we show that the oncogene dMyc is involved in the upregulation of these transporters, highlighting the important link between oncogenes and metabolic transporters in the regulation of tumor growth.

Check out our newest open-access paper on dMyc-dependent upregulation of heterodimeric amino acid transporters and their role in Drosophila brain tumor growth! link.springer.com/article/10.100…