Bashiri Lab

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The Biosynthetic Pathway to the Pyrroloiminoquinone Marine Natural Product Ammosamide C | Journal of the American Chemical Society @UofIllinois pubs.acs.org/doi/10.1021/ja…

This is a very cool study! A new antibiotic, a new mechanism of action, unlocking new ribosome biology!

Online now! Allosteric regulation of fungal fatty acid synthesis dlvr.it/TNQwwJ

Mycobacterium tuberculosis growth arrest on propionate at acidic pH is suppressed by mutations in phoPR and pyrazinamide treatment biorxiv.org/content/10.110…

Thrilled to share our latest paper now out in @ScienceMagazine 🎉🤩 We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era 💊 science.org/doi/10.1126/sc…

@gle_evans @Jodie_JMJLab The interactive tool is super handy, and the structure brings some memories for sure 😄 Thanks for sharing Genevieve @gle_evans

How do you think MenD looks on the new PDBe pages? 🔗 ebi.ac.uk/pdbe/entry/pdb… Jodie @Jodie_JMJLab? Ghader @BashiriLab?

New pages (at PDBe.org) to highlight cool things observed in a protein or 🧬 or RNA structure? Take my inner-nerd to my happy place 😀 Thank you to my many hardworking @PDBeurope colleagues who brought these into existence!!

How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint! biorxiv.org/content/10.110…

Attending Queenstown Research Week? Join @CARB_X Chief Scientific Officer Richard Alm, PhD, for his presentation “CARB-X – Accelerating the Development of Novel Products to Tackle AMR.” 📆 Wednesday, September 3 ⏰ 3:30 PM NZST

Out Now! Deep learning reveals antibiotics in the archaeal proteome bit.ly/4lpohMM #DeepLearning #ArtificialIntelligence #Antibiotics

Here’s our latest biosynthetic study on swainsonine, nature.com/articles/s4158… — a pathway far more complex than expected and packed with enzymes brimming with synthetic potential. Led by our fantastic postdoc, @shaonan_liu, who will soon be starting his own lab in Shenzhen!

August 2025 NZSBMB news - mailchi.mp/6af317d64c8c/a…

@GHITFund @AdaptVac @UMS_EcoCampus @AucklandUni @LPIXEL_Inc Humbled and pleased to receive funding from @GHITFund to explore new targets against #TB. Many thanks to our collaborators @UTokyo_News_en and @otago and support from @AucklandUni @ScienceUoA @UniServicesNZ

[Press Release📢] The GHIT Fund announced today a total investment of approx. USD 7.3 million in #malaria and #TB R&D projects. Four new partners, @AdaptVac @UMS_EcoCampus @AucklandUni @LPIXEL_Inc have joined us! Together with 190 partners, we’re accelerating solutions to global health challenges. More 👉  ghitfund.org/newsroom/press…

Join @CARB_X Chief Scientific Officer Richard Alm, PhD at a @MTPConnect_AUS panel discussing innovation in antibiotic R&D, sharing insights on translating AMR research into real-world solutions. 📆 Monday, July 14 ⏰ 12 – 2 PM ACST 🔗 Register now: bit.ly/4kWKp1x

If you have 30 minutes or so, listen to my recently finished honours student Sarah talking about her project. plantandfood.com/en-nz/article/…

A recent @OpenAccessGov piece by Melissa Gong Mitchell of @AMRAlliance highlighted the urgent need to fix the broken antibiotic R&D pipeline and the role of push incentives like @CARB_X in driving early-stage R&D. 🔗 Read more: bit.ly/43ZWj3e #AMR #StopSuperbugs

Introducing Bonnie Murphy, Ville Kaila, Maxie Roessler, Volha Chukhutsina, Alisia Fadini, Sonya Hanson, Filipe Maia, and Kirill Kovalev dlvr.it/TKbj4s

@Dr_Rose_Gold @Ferrier_Inst @J_A_C_S Fantastic work Rose et al, congrats.

Thrilled to share our work that reveals unusual biosynthetic machinery for the core architecture of radarin indole-diterpenoids! Check out the incredibly complex cyclisation chemistry by the noncanonical terpene cyclase RadB.😊 @Ferrier_Inst @J_A_C_S pubs.acs.org/doi/10.1021/ja…

Non-Canonical Type II Terpene #Cyclases Deliver Rare Terpenoid Architectures by Rose M. McLellan (@Dr_Rose_Gold), Daniel Berry, Rosannah C. Cameron, and Emily J. Parker at @Ferrier_Inst in @J_A_C_S pubs.acs.org/doi/10.1021/ja…