

Beekman Lab
30 posts

@BeekmanLab
Studying the world of single-cell and epigenomics in cancer development @CRGenomica @_BIST



📢 JobOpenings #CRG 👉 Research Indicators Manager ⏳ Feb 4 🔗 ow.ly/5hpt50QutJe 👉 Postdoc - Advanced Fluorescence Microscopy ⏳ Feb 12 🔗 ow.ly/mOOU50QutJc 👉 Postdoc - Gene Regulation during Lymphoma Formation ⏳ Feb 25 🔗 ow.ly/L44o50QutJa



🧬 Each Cancer Has Its Origin Story. Just Ask a Cell’s ‘Diary’ DNA methylation acts like a cell’s personal diary. Reading this information can unlock the next generation of therapies for diseases like cancer. So why haven’t we unlocked this gold mine of information yet?

🧬 Each Cancer Has Its Origin Story. Just Ask a Cell’s ‘Diary’ DNA methylation acts like a cell’s personal diary. Reading this information can unlock the next generation of therapies for diseases like cancer. So why haven’t we unlocked this gold mine of information yet?


Do you want to know about using DNA methylation to study cell identity, proliferation, genome activation history, or tumor cell of origin in single cells? Check out our review! frontiersin.org/articles/10.33… #DNAmethylation #SingleCell #hematopoiesis

After a great discussion with @renee_beekman and @Agos_Bianchi_, we wrapped up our thoughts about DNA methylation, hematopoiesis, and single-cell methods in this new opinion article! frontiersin.org/articles/10.33… Here a thread with its content 🧵 (1/6) #SingleCell #hematopoiesis









I am happy to share scTAM-seq, now out in @GenomeBiology 🎉! Our method allows targeted high-confidence analysis of DNA methylation at single-CpG resolution across thousands of cells. Great to work with @scherermich @larsplus and @renee_beekman genomebiology.biomedcentral.com/articles/10.11…