Conor Walker

56 posts

Conor Walker

@BioConorWalker

Bioinformatics Scientist. Formerly postdoc at @nygenome/@Columbia and PhD @emblebi/@Cambridge_Uni.

New York, NY شامل ہوئے Mart 2017

682 فالونگ149 فالوورز

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Gamze Gürsoy@gamzeandgursoy·2 Eki

Super excited to share my lab's latest work on quantifying the private information leakage from single cell count matrices. Led by very first postdoc in the g2lab, brilliant @BioConorWalker, we showed that individuals can be reidentified 1/n cell.com/cell/fulltext/…

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Anoushka@noush_joglekar·9 Nis

If you were looking for evidence that isoforms are cool, all-pervasive in the 🧠, and everybody should study them at the single cell level, our work on mouse development and brain-region variability from the @hagentilgner lab is now live @NatureNeuro! 1/ nature.com/articles/s4159…

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Nicola De Maio@Nicola_De_Maio·20 Tem

A few months ago we posted a pre-print regarding a new approach to likelihood-based phylogenetics at short divergence scales (e.g. genomic epidemiology). I have now further optimized the code and updated the preprint doi.org/10.1101/2022.0…

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Erik Garrison@erikgarrison·10 Tem

We've made a draft human pangenome! 47 haplotype-resolved assemblies, two reference genomes, and five pangenome graphs!

bioRxiv@biorxivpreprint

A Draft Human Pangenome Reference biorxiv.org/cgi/content/sh… #bioRxiv

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Shai Carmi@ShaiCarmi·27 May

This is a brilliant preprint. It describes an experimental method for separately sequencing the paternal and maternal genomes. This goes beyond the standard "experimental phasing" - the method can also tell which chr is maternal and which is paternal. biorxiv.org/content/10.110…

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Hakhamanesh Mostafavi@Hakha_Most·9 May

We've known for a long time that a large fraction of noncoding GWAS hits are not currently explained by eQTLs. Why?? I'm excited to share our new preprint on this! Take home: GWAS and eQTL assays maximize power for different types of variants. (1/n) biorxiv.org/content/10.110…

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Zamin Iqbal@ZaminIqbal·23 Mar

Groundbreaking work from @Nicola_De_Maio @EBIgoldman and colleagues "we rewrite the classical Felsenstein pruning algorithm so that we can infer phylogenetic trees on at least 10 times larger datasets with higher accuracy than existing maximum likelihood methods. "

bioRxiv Bioinfo@biorxiv_bioinfo

Maximum likelihood pandemic-scale phylogenetics biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

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Mat Legut, PhD@MatLegut·16 Mar

Really chuffed to share our latest work from Sanjana Lab out in @nature today (nature.com/articles/s4158…). We tested >12,000 genes to find positive regulators of T cell proliferation to be used for next-gen #immunotherapies. A thread...

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Conor Walker@BioConorWalker·18 Oca

A huge thank you to @Nick_Goldman, @aylwyn_scally, @Nicola_De_Maio, and members of @EBIgoldman for their supervision and support during my #PhD.

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Conor Walker@BioConorWalker·18 Oca

Looking forward to starting my new position with @gamzeandgursoy at @nygenome! I will be working on developing methods for genomic #privacy. g2lab.org/people/

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Goldman Group@EBIgoldman·24 Eyl

Simulating pandemic-scale genome sequencing datasets, e.g to benchmark your new analysis methods? Try phastSim, now updated to include indels (biorxiv.org/content/10.110…) [1/2]

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josé@zga_aaa·13 Ağu

Glad to see this out. Here, we track ~700 clones across >300 individuals over ~13 years to unravel key aspects of clonal haematopoiesis (when there are genetically-defined subpopulations of haematopoietic stem cells in your bone marrow).

bioRxiv@biorxivpreprint

The longitudinal dynamics and natural history of clonal haematopoiesis biorxiv.org/cgi/content/sh… #bioRxiv

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EvolCompGen@EvolComp·6 Ağu

Congrats to the 2021 @EvolComp Talk & Poster awardees for #ismbeccb2021 Best talk - Elise Parey (@CamLBerthelot lab) Best poster - Vignesh Sridhar (@Vigs_24, @JRaviLab) Honorable mentions Talks - @punto_c @BioConorWalker @matteodelabre Posters - @elliotmajlessi

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Goldman Group@EBIgoldman·3 Ağu

We are still looking to hire a postdoc bioinformatician on this fascinating project. Please read/RT/pass on to anyone who might be interested: twitter.com/emblebi/status…

EMBL-EBI@emblebi

🎉 Congratulations on recent @EU_Commission @HorizonEU funding awarded to researchers at @IITalk, @uni_lu, @CNRS, @UniPadova and EMBL-EBI’s @EBIgoldman and colleagues. Find out more 👇 ebi.ac.uk/about/news/pre…

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Goldman Group@EBIgoldman·15 Tem

We are re-advertising this position! Please check-out 👇 the original thread 👇, pass to anyone you think might be interested, share with colleagues, RT ... twitter.com/EBIgoldman/sta…

Goldman Group@EBIgoldman

Postdoc position in @EBIgoldman Group at @emblebi, to join new multinatl collab project creating proof-of-principle high-throughput nanopore device for determining amino acid sequence and identity of proteins Full details at embl.org/jobs/position/… <1/2>

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Goldman Group@EBIgoldman·11 May

The impressively huge scale of SARS-CoV-2 sequencing has really stretched our ability to do phylogenetics, and is leading to some fantastic advances in methods. Here's one that @Nicola_De_Maio from the @EBIgoldman group at @emblebi contributed to. twitter.com/emblebi/status…

EMBL-EBI@emblebi

#SARSCoV2 is spreading through human populations & evolving. Ultrafast Sample placement on Existing tRees (UShER) is a game-changing new tool which can be used to track this evolution in real time & reconstruct the source of new cases. @NatureGenet @ucsc nature.com/articles/s4158…

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Goldman Group@EBIgoldman·7 May

Last call; closing date on Monday. Please apply! If you don't apply, at least promise me you'll RT or pass to a friend. twitter.com/EBIgoldman/sta…

Goldman Group@EBIgoldman

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Goldman Group@EBIgoldman·20 Nis

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Conor Walker@BioConorWalker·24 Mar

@Nicola_De_Maio @uperron3 In Too Deep for sure... also maybe Break Stuff

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Nicola De Maio@Nicola_De_Maio·23 Mar

@uperron3 @BioConorWalker any songs about selection?

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Umberto Perron@uperron3·23 Mar

this article is and example of the emergence two hopeful trends: #MachineLearning for #phylogenetics and early '00s music puns. I wholeheartedly approve biorxiv.org/content/10.110…

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Goldman Group@EBIgoldman·19 Mar

For those of you who love to explain complex mutation clusters parsimoniously (who doesn't?), the final version of @BioConorWalker's paper is now out at journals.plos.org/plosgenetics/a… - also feat. @aylwyn_scally and @Nicola_De_Maio. And me. Cool figures too: this 👇 is part of S.Fig 10

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دریافت کریں

@hagentilgner @NatureNeuro @Nicola_De_Maio @EBIgoldman @Nature @Nick_Goldman @aylwyn_scally @gamzeandgursoy