Lukas Scheiderer

🎉Just out in @NaturePhotonics : rdcu.be/ecthU Our Review describing the revolutionary principle behind #MINFLUX🔬, summarizing major imaging and tracking breakthroughs and giving an outlook on future advancements. Big thanks to @JonasRies & @zacsimile. @MaxPerutzLabs

What's the crux of #MINFLUX?🔬 How does it achieve molecular resolution with few fluorescent photons?🤯 What has it achieved so far? What are strengths🦾 & limitations? Find out in our review (arxiv.org/abs/2410.15902) with @zacsimile & @JonasRies at @MaxPerutzLabs. #cryoEM

Out in @naturemethods: #MINSTED tracks #kinesin with much greater signal-to-background ratios (SBR, see Fig 2j,Table 4) than #MINFLUX and observes intriguing protofilament switches: t.ly/qEVim @StefanHellLabs @mpi_mr_hd

Do you know the popular animations of #kinesin walking? Dual-color #MINFLUX shows: it rather either dances Viennese waltz💃 or with 𝐧𝐨𝐯𝐞𝐥 Chassé steps🕺. Full amazing animation in supplements: t.ly/Z8Kyl. @StefanHellLabs @mpi_mr_hd @Stefan_W_Hell