Oxidant and Inflammation Biology group

Dr Mark Miles (@DrMark91) represented OXIB at @ASImmunology, where he presented his latest research on the dual role of TLR7 in regulating inflammation and lung function during viral respiratory infection. #ASI2025 #ASImmunology

Xinyue from @OXIBgroup is determining the role of CD4+ T cells in mediating vascular inflammation and dysfunction during gestational influenza infection

Ameanah from @OXIBgroup is exploring the lipdifferential temporal immune responses to influenza A virus and pattern recognition receptors stimulation in lung epithelial cells and macrophages

Paneet from @OXIBgroup is investigating how prenatal and early life viral infections disrupt the blood brain barrier integrity and increase the risk of long-term neurodevelopment abnormalities

🫁 Excellent work on Influenza A virus driving TLR-dependent inflammatory responses in non-small cell lung cancer. This exciting research was brought to us by Isabella Rosano from @RMIT #YoungVIIN2025 #VIINYIS

@The_VIIN @RMIT Great work, Isabella!

Last Friday, Isabella had the opportunity to showcase her Honours project on how influenza A virus drives TLR7-dependent responses in non-small cell lung cancer at the #YoungVIIN2025 symposium. It was a great moment for Isabella and our lab! @The_VIIN #viinyis #IAV #flu #cancer

Great work Isabella on presenting your exciting data on the effects of influenza A virus infection in non-small cell lung cancer. #Honours #RMIT #IAV #lungcancer

Congratulations to Dr Stella Liong and Dr Hao Wang for receiving the Outstanding Contribution to Research & Innovation (Early Career) and Certificate of Commendation, respectively. Their hard work was recognised today at @RMIT SHBS Staff Forum.

Removing TLR7 reduced these sex-based differences, suggesting TLR7 may shape how males and females fight RSV. #RSV #TLR7 #Immunology #SexDifferences mdpi.com/1999-4915/17/3…

#ResearchSpotlight: New research led by @DrMark91 and @noxbiology from @OXIBgroup reveals TLR7 helps drive stronger immune responses to RSV infection in females, including higher cytokine and antibody levels. mdpi.com/1999-4915/17/3…

Today was a beautiful day to be pushing the boundaries of science! #OXIB #Research #Science

Today was a beautiful day to be pushing the boundaries of science! #Honours #PhD #Research

It drives harmful lung inflammation and dysfunction early on but helps to control Th2-mediated chronic airway hyperreactivity. #Influenza #Immunology #TLR7 mdpi.com/1422-0067/25/2…

#ResearchSpotlight: Research led by @DrMark91 and @noxbiology in collaboration with @UniversitySA and @TrinityCollege uncovers a double-edged role of TLR7 in influenza infections. 🦠

Congratulations to @DrMark91 on being awarded the Maxwell Eagle Endowment Award for Cancer Research. A great note to end the year on!

Still a lot to learn about RNA-sensing in virus infection! Ameanah El-Hennawi from @RMIT presented some unexpected RIG-I and TLR7 responses to #flu infection in macrophages vs epithelial cells @The_VIIN #VIINYIS #YoungVIIN2024

More great Science Bites at @The_VIIN #VIINYIS #YoungVIIN2024. Thomas Huttmann from @RMIT_CRSH TLR7-linked sex-diffs in response to #RSV, a critically rising airborne pathogen; and Andrew Verich from @KirbyInstitute employing #machinelearning to improve diagnosis of #gonorrhoeae

More work on TLR7 from @RmitSciences @ResearchRMIT Great talk from Honours student Ameanah El-Hennawi who's looking at the role of TLR7 in macrophages during Influenza infection #VIINYIS #YoungVIIN2024 @The_VIIN

Our honours students presenting at the VIIN Young Investigator Symposium. Well done all! #viinyis #YoungVIIN2024 @The_VIIN @MIPS_Australia