Philipp Keller

Thrilled to finally share! The plant microbiota triggers dose-dependent immune responses that feed back to influence bacterial colonization. This affects non-pathogenic and pathogenic strains, impacting microbiota homeostasis. Out today in @NaturePlants: doi.org/10.1038/s41477…

Exciting news! 🤩 I will start a research group @LeibnizHKI next year! We will investigate (antimicrobial) natural products involved in interactions in the moss microbiome – a promising but so far understudied habitat 🌱🧫 Funded by @tmwwdg, @EU_Sozialfonds Plus, @aufbaubank 🙏

ETH researchers have developed bacteria that efficiently utilize methanol, offering a sustainable alternative to producing valuable products currently derived from fossil fuels. 🛢️ @ETH_DBIOL #FossilFuels #ClimateNeutral brnw.ch/21wJ52g

@mRetier @TomGassler @TimothyBra91929

Towards a #circulareconomy ! Here, we show the production of 4 chemicals from different metabolic nodes and highlight the potential of our synthetic methylotrophic E. coli. Thanks to everyone that was evolved!;) It was a great team effort! @ETH_en #peer-review" target="_blank" rel="nofollow noopener">nature.com/articles/s4192…

Recently, @PhilippPk & I developed a synthetic methylotroph in the Vorholt lab to convert green methanol to carbon-negative chemicals. Thrilled to share that we now received the SNF/Innosuisse BRIDGE Discovery grant to support translating our tech to industry. #climateChange

💻We just updated Dashing Growth Curves with additional features and improved performance. 🦠If you’re looking for an easy-to-use tool for rapid analysis of microbial growth check out dashing-growth-curves.ethz.ch

Exciting preprint by the lab of @CeciMGLab! They describe the discovery and structure of "methylolanthanin", a metal chelator secreted by Methylobacterium for the uptake of lanthanides!

Predicting interactions in plant microbiomes made possible. Metabolic modelling sheds light on bacterial interactions in planta, see the recent work by Vorholt Lab @ETH_en and @realLCSB at EPFL. More: doi.org/10.1126/scienc…

Check out our new story on TyrEx Cycloaddition on enzymatic generation of dienophiles in bacteria and how to use these for protein conjugation, now out in @NatureChemistry! Great work from @EdgarsLakis and @danirichterfl at @piel_lab. nature.com/articles/s4155…

Last PhD study is out in @jbiolchem ! We probed coenzyme metabolism by adding vitamins to culture media. It was fun to do, and it turns out one of the vitamins goes through a degradation-reconstitution cycle previously unidentified. doi.org/10.1016/j.jbc.…

Congratulations to Chantal Ernst and @GabrielGiger from the #VorholtLab, who both received the best short talk award at the #EESSymbiosis!

Excited to share our latest work, led by Noa Barak-Gavish, showing how opportunistic bacteria modulate their lifestyle from coexistence to pathogenicity by perceiving the physiological state of their algal host through sensing of algal secreted metabolites elifesciences.org/articles/84400

Thank you @JethroHemmann and the other collaborators for the great team effort!!

Did you know that rare-earth elements are utilized by some bacteria?🦠😍 In this paper @jbiolchem, we describe the lanthanide response of the methylotroph Methylobacillus flagellatus and the discovery of lanpepsy, a novel lanthanide-binding protein.🤗 jbc.org/article/S0021-…

New tool for everyone studying microbial growth! After one too many tedious sessions analyzing growth curves in Excel or Python, I decided to build a better solution. Dashing Growth Curves dashing-growth-curves.ethz.ch is an easy-to-use web app that accelerates growth curve analysis👇

New tool for studying microbial growth! My co-worker @mRetier created an online tool to quickly analysis growth curves from hundreds of samples. This can save you a lot of time! Check it out here: dashing-growth-curves.ethz.ch

@BirgittaRyback @mRetier @TomGassler @NatureComms Thank you @BirgittaRyback

@PhilippPk @mRetier @TomGassler @NatureComms Congrats, Philipp!

Towards the methanol economy! We turned the biotech workhorse E. coli into an organism that can just live on methanol! Tremendously enjoyed the team effort @mRetier @TomGassler and everyone else involved! @NatureComms nature.com/articles/s4146…

Thank you @JethroHemmann